{
  "_id": "6a1aebb91d7bb097a09f3ffd",
  "Package": "SimBu",
  "Title": "Simulate Bulk RNA-seq Datasets from Single-Cell Datasets",
  "Version": "1.15.0",
  "Authors@R": "person(given = \"Alexander\",\nfamily = \"Dietrich\",\nrole = c(\"aut\", \"cre\"),\nemail = \"alex.dietrich@tum.de\")",
  "Description": "SimBu can be used to simulate bulk RNA-seq datasets with\nknown cell type fractions. You can either use your own\nsingle-cell study for the simulation or the sfaira database.\nDifferent pre-defined simulation scenarios exist, as are\noptions to run custom simulations. Additionally, expression\nvalues can be adapted by adding an mRNA bias, which produces\nmore biologically relevant simulations.",
  "License": "GPL-3 + file LICENSE",
  "Encoding": "UTF-8",
  "Roxygen": "list(markdown = TRUE)",
  "RoxygenNote": "7.2.3",
  "URL": "https://github.com/omnideconv/SimBu",
  "BugReports": "https://github.com/omnideconv/SimBu/issues",
  "VignetteBuilder": "knitr",
  "Config/testthat/edition": "3",
  "StagedInstall": "no",
  "biocViews": "Software, RNASeq, SingleCell",
  "Config/pak/sysreqs": "libglpk-dev make libicu-dev libpng-dev libxml2-dev\npython3 zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:58:50 UTC",
  "RemoteUrl": "https://github.com/bioc/SimBu",
  "RemoteRef": "HEAD",
  "RemoteSha": "e4a5ee259a3bee5cc6b4fa3e2ed77e85a751c516",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 09:39:06 UTC",
    "User": "root"
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  "Author": "Alexander Dietrich [aut, cre]",
  "Maintainer": "Alexander Dietrich <alex.dietrich@tum.de>",
  "MD5sum": "83db5796dc281407f25e419947ef9a95",
  "_user": "bioc",
  "_type": "src",
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  "_created": "2026-05-30T09:39:06.000Z",
  "_published": "2026-05-30T13:52:57.182Z",
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    "description": "PhD student in Bioinformatics\nChair of Experimental Bioinformatics, TUM",
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    "name": "Bioconductor",
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      "title": "Applies the Census count transformation on a count matrix",
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      "title": "Build SummarizedExperiment using local annotation and count matrix R objects",
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      "title": "setup the sfaira package",
      "topics": [
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      "title": "SimBu: Bias-aware simulation of bulk RNA-seq data with variable cell type composition",
      "topics": [
        "SimBu"
      ]
    },
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      "title": "Simulate whole pseudo-bulk RNAseq dataset",
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