{ "_id": "6a493f9ca19c9318096e8168", "Package": "SigsPack", "Type": "Package", "Title": "Mutational Signature Estimation for Single Samples", "Version": "1.27.0", "Author": "Franziska Schumann ", "Maintainer": "Franziska Schumann ", "Description": "Single sample estimation of exposure to mutational\nsignatures. Exposures to known mutational signatures are\nestimated for single samples, based on quadratic programming\nalgorithms. Bootstrapping the input mutational catalogues\nprovides estimations on the stability of these exposures. The\neffect of the sequence composition of mutational context can be\ntaken into account by normalising the catalogues.", "License": "GPL-3", "Encoding": "UTF-8", "biocViews": "SomaticMutation, SNP, VariantAnnotation,\nBiomedicalInformatics, DNASeq", "VignetteBuilder": "knitr", "BiocViews": "", "BugReports": "https://github.com/bihealth/SigsPack/issues", "URL": "https://github.com/bihealth/SigsPack", "Collate": "bootstrap_mut_catalogues.R cosmicSigs.R sigProfilerExome.R\nsigProfiler20190522.R create_mut_catalogues.R decomposeQP.R\nget_context_freq.R hg19context_freq.R normalize.R\nplot_bootstrapped_exposure.R signature_exposure.R\nsummarize_exposures.R vcf2mut_cat.R", "RoxygenNote": "6.1.1", "LazyData": "true", "Config/pak/sysreqs": "make libbz2-dev liblzma-dev libpng-dev libxml2-dev\nlibssl-dev xz-utils zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:50:44 UTC", "RemoteUrl": "https://github.com/bioc/SigsPack", "RemoteRef": "HEAD", 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