{ "_id": "6a153bf3acfb0bcc41d52f27", "Package": "SOMNiBUS", "Title": "Smooth modeling of bisulfite sequencing", "Version": "1.21.0", "Authors@R": "c(person(\"Kaiqiong\", \"Zhao\", role = \"aut\", \nemail = \"kaiqiong.zhao@mail.mcgill.ca\"),\nperson(\"Kathleen\", \"Klein\", role = \"cre\",\nemail = \"kathleen.klein@mail.mcgill.ca\"),\nperson(\"Audrey\", \"Lemaçon\", role = c(\"ctb\",\"ctr\"),\nemail = \"audrey@mims.ai\"),\nperson(\"Simon\", \"Laurin-Lemay\", role = c(\"ctb\",\"ctr\"),\nemail = \"simon@mims.ai\"),\nperson(\"My Intelligent Machines Inc.\", role = \"ctr\"),\nperson(\"Celia\", \"Greenwood\" , role = c(\"ths\", \"aut\"),\nemail = \"celia.greenwood@mcgill.ca\")\n)", "Description": "This package aims to analyse count-based methylation data\non predefined genomic regions, such as those obtained by\ntargeted sequencing, and thus to identify differentially\nmethylated regions (DMRs) that are associated with phenotypes\nor traits. The method is built a rich flexible model that\nallows for the effects, on the methylation levels, of multiple\ncovariates to vary smoothly along genomic regions. At the same\ntime, this method also allows for sequencing errors and can\nadjust for variability in cell type mixture.", "License": "MIT + file LICENSE", "URL": "https://github.com/kaiqiong/SOMNiBUS", "BugReports": "https://github.com/kaiqiong/SOMNiBUS/issues", "VignetteBuilder": "knitr", "biocViews": "DNAMethylation, Regression, Epigenetics,\nDifferentialMethylation, Sequencing, FunctionalPrediction", "Encoding": "UTF-8", "Language": "en-US", "Roxygen": "list(markdown = TRUE)", "RoxygenNote": "7.3.2", "Config/pak/sysreqs": "make libbz2-dev libicu-dev liblzma-dev libpng-dev\nlibxml2-dev libssl-dev libx11-dev xz-utils zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:54:52 UTC", "RemoteUrl": "https://github.com/bioc/SOMNiBUS", "RemoteRef": "HEAD", "RemoteSha": "8ae13398aefe404f3015729a8c235a6dbb9c6c98", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-26 06:05:23 UTC", "User": "root" }, "Author": "Kaiqiong Zhao [aut],\nKathleen Klein [cre],\nAudrey Lemaçon [ctb, ctr],\nSimon Laurin-Lemay [ctb, ctr],\nMy Intelligent Machines Inc. 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