{ "_id": "6a33d9123efcd9bda43b694a", "Package": "RNAsense", "Type": "Package", "Title": "Analysis of Time-Resolved RNA-Seq Data", "Version": "1.27.0", "Authors@R": "c(person(\"Marcus\", \"Rosenblatt\", email = \"marcus.rosenblatt@gmail.com\", role = \"cre\"),\nperson(\"Gao\", \"Meijang\", role = \"aut\"),\nperson(\"Helge\", \"Hass\", role = \"aut\"),\nperson(\"Daria\", \"Onichtchouk\", role = \"aut\"))", "Description": "RNA-sense tool compares RNA-seq time curves in two\nexperimental conditions, i.e. wild-type and mutant, and works\nin three steps. At Step 1, it builds expression profile for\neach transcript in one condition (i.e. wild-type) and tests if\nthe transcript abundance grows or decays significantly. Dynamic\ntranscripts are then sorted to non-overlapping groups (time\nprofiles) by the time point of switch up or down. At Step 2,\nRNA-sense outputs the groups of differentially expressed\ntranscripts, which are up- or downregulated in the mutant\ncompared to the wild-type at each time point. At Step 3,\nCorrelations (Fisher's exact test) between the outputs of Step\n1 (switch up- and switch down- time profile groups) and the\noutputs of Step2 (differentially expressed transcript groups)\nare calculated. The results of the correlation analysis are\nprinted as two-dimensional color plot, with time profiles and\ndifferential expression groups at y- and x-axis, respectively,\nand facilitates the biological interpretation of the data.", "License": "GPL-3", "Encoding": "UTF-8", "LazyData": "false", "RoxygenNote": "6.1.1", "BugReports": "https://github.com/marcusrosenblatt/RNAsense", "biocViews": "RNASeq, GeneExpression, DifferentialExpression", "VignetteBuilder": "knitr", "Config/pak/sysreqs": "libicu-dev zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:51:23 UTC", "RemoteUrl": "https://github.com/bioc/RNAsense", "RemoteRef": "HEAD", "RemoteSha": "329cc51125c26c3d432d04dc7f71ce033167eb7e", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-18 11:26:10 UTC", "User": "root" }, "Author": "Marcus Rosenblatt [cre],\nGao Meijang [aut],\nHelge Hass [aut],\nDaria Onichtchouk [aut]", "Maintainer": "Marcus Rosenblatt ", "MD5sum": 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