{ "_id": "6a1a74761d7bb097a09d16fa", "Package": "QUBIC", "Type": "Package", "Title": "An R Package for Qualitative Biclustering in Support of Gene\nCo-Expression Analyses", "Description": "The core function of this R package is to provide the\nimplementation of the well-cited and well-reviewed QUBIC\nalgorithm, aiming to deliver an effective and efficient\nbiclustering capability. This package also includes the\nfollowing related functions: (i) a qualitative representation\nof the input gene expression data, through a well-designed\ndiscretization way considering the underlying data property,\nwhich can be directly used in other biclustering programs; (ii)\nvisualization of identified biclusters using heatmap in support\nof overall expression pattern analysis; (iii) bicluster-based\nco-expression network elucidation and visualization, where\ndifferent correlation coefficient scores between a pair of\ngenes are provided; and (iv) a generalize output format of\nbiclusters and corresponding network can be freely downloaded\nso that a user can easily do following comprehensive functional\nenrichment analysis (e.g. DAVID) and advanced network\nvisualization (e.g. Cytoscape).", "Authors@R": "c(person(\"Yu\", \"Zhang\", role = c(\"aut\", \"cre\"), email = \"zy26@jlu.edu.cn\"),\nperson(\"Qin\", \"Ma\", role = \"aut\", email = \"qin.ma@sdstate.edu\"))", 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