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  "Description": "Peptide Set Test (PepSetTest) is a peptide-centric\nstrategy to infer differentially expressed proteins in LC-MS/MS\nproteomics data. This test detects coordinated changes in the\nexpression of peptides originating from the same protein and\ncompares these changes against the rest of the peptidome.\nCompared to traditional aggregation-based approaches, the\npeptide set test demonstrates improved statistical power, yet\ncontrolling the Type I error rate correctly in most cases. This\ntest can be valuable for discovering novel biomarkers and\nprioritizing drug targets, especially when the direct\napplication of statistical analysis to protein data fails to\nprovide substantial insights.",
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  "Date/Publication": "2026-04-28 13:03:21 UTC",
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