{
  "_id": "6a1ab1d31d7bb097a09d5ab6",
  "Package": "PREDA",
  "Version": "1.59.0",
  "Title": "Position Related Data Analysis",
  "Author": "Francesco Ferrari <francesco.ferrari@ifom.eu>",
  "Maintainer": "Francesco Ferrari <francesco.ferrari@ifom.eu>",
  "License": "GPL-2",
  "Description": "Package for the position related analysis of quantitative\nfunctional genomics data.",
  "Collate": "AllClasses.R AllGenerics.R analysesNames.R\nCleanNAAnnotationDataframe.R\ncompareFunctionFromStatisticsForPREDA.R\ncomputeDatasetSignature.R DataForPREDA2dataframe.R\nDataForPREDA2GenomicAnnotationsForPREDA.R\nDataForPREDA2StatisticsForPREDA.R datasetSignatureFromFlags.R\neset2GenomicAnnotations.R GE_computeStatistic.R\nGEhighWeakExpressionWorkflow.R genomePlot_improved.R\ngenomePlot.R GenomicAnnotations2dataframe.R\nGenomicAnnotations2GenomicAnnotationsForPREDA.R\nGenomicAnnotations2reference_positions.R\nGenomicAnnotationsExtract.R GenomicAnnotationsFilter_neg.R\nGenomicAnnotationsFilter_pos.R\nGenomicAnnotationsForPREDA2dataframe.R\nGenomicAnnotationsForPREDA2GenomicAnnotations.R\nGenomicAnnotationsForPREDA2PREDAResults.R\nGenomicAnnotationsForPREDAFromfile.R\nGenomicAnnotationsForPREDAGetExpectedFlags.R\nGenomicAnnotationsFromdataframe.R GenomicAnnotationsFromfile.R\nGenomicAnnotationsFromLibrary.R\nGenomicAnnotationsSortAndCleanNA.R GenomicRegions2dataframe.R\nGenomicRegionsAnnotate.R GenomicRegionsChrNumber.R\nGenomicRegionsComparison.R GenomicRegionsCreateRegionsIds.R\nGenomicRegionsFilter_neg.R GenomicRegionsFilter_pos.R\nGenomicRegionsFindOverlap.R GenomicRegionsFromdataframe.R\nGenomicRegionsFromfile.R GenomicRegionsNumber.R\nGenomicRegionsSpan.R GenomicRegionsTotalSpan.R\nGEsimulationsWorkflow.R getExpectedSmoothFunction.R\ngetExpectedSmoothFunction_runmean.R getObservedSmoothFunction.R\ngetObservedSmoothFunction_runmean.R getStatisticByName.R\ninitialize-methods.R MergeStatisticAnnotations2DataForPREDA.R\nPREDADataAndResults2dataframe.R PREDA_main_permRows.R\nPREDA_main_permSamples.R PREDA_main.R\nPREDA_multTestCorrection.R PREDA_quantsmoothStatPerm.R\nPREDA_quantsmoothStat.R PREDAResults2dataframe.R\nPREDAResults2GenomicRegions.R\nPREDAResults2GenomicRegionsSingle.R\nPREDAResults2PREDADataAndResults.R\nPREDAResultsGetObservedFlags.R PREDA_smoothStatPerm.R\nPREDA_smoothStat.R PREDA_splineStatPerm.R PREDA_splineStat.R\npreprocessingGE.R RMAwithCDFfilter.R simulations.R\nSODEGIR_GEstatistics.R SODEGIRpreprocessingGE.R\nSortAnnotationDataframe.R StatisticsForPREDA2dataframe.R\nStatisticsForPREDAFilterColumns_neg.R\nStatisticsForPREDAFilterColumns_pos.R\nStatisticsForPREDAFromdataframe.R statisticsForPREDAfromEset.R\nStatisticsForPREDAFromfile.R",
  "biocViews": "Software, CopyNumberVariation, GeneExpression, Genetics",
  "Config/pak/sysreqs": "libpng-dev libxml2-dev libssl-dev zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:35:39 UTC",
  "RemoteUrl": "https://github.com/bioc/PREDA",
  "RemoteRef": "HEAD",
  "RemoteSha": "e2b68a82ee67ba5df66e47042b6629ca1daf9256",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 07:07:23 UTC",
    "User": "root"
  },
  "MD5sum": "e84295ff6d834fe49c5ebf74bd05630b",
  "_user": "bioc",
  "_type": "src",
  "_file": "PREDA_1.59.0.tar.gz",
  "_fileid": "3aab81283399004a29132de4b740d510f1e5e132e3da65b94bf1422dc56c9f4d",
  "_filesize": 2083997,
  "_sha256": "3aab81283399004a29132de4b740d510f1e5e132e3da65b94bf1422dc56c9f4d",
  "_created": "2026-05-30T07:07:23.000Z",
  "_published": "2026-05-30T09:45:55.307Z",
  "_jobs": [
    {
      "job": 78632406327,
      "time": 187,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "ERROR",
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    {
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      "config": "linux-devel-x86_64",
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  ],
  "_bioccheck": {
    "error": 3,
    "warning": 5,
    "note": 20
  },
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/26677568764",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/PREDA",
  "_commit": {
    "id": "e2b68a82ee67ba5df66e47042b6629ca1daf9256",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777379739
  },
  "_maintainer": {
    "name": "Francesco Ferrari",
    "email": "francesco.ferrari@ifom.eu",
    "login": "fferrari",
    "description": "",
    "uuid": 5503961
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.9.0",
      "role": "Depends"
    },
    {
      "package": "Biobase",
      "role": "Depends"
    },
    {
      "package": "lokern",
      "version": ">= 1.0.9",
      "role": "Depends"
    },
    {
      "package": "multtest",
      "role": "Depends"
    },
    {
      "package": "stats",
      "role": "Depends"
    },
    {
      "package": "methods",
      "role": "Depends"
    },
    {
      "package": "annotate",
      "role": "Depends"
    },
    {
      "package": "quantsmooth",
      "role": "Suggests"
    },
    {
      "package": "qvalue",
      "role": "Suggests"
    },
    {
      "package": "limma",
      "role": "Suggests"
    },
    {
      "package": "caTools",
      "role": "Suggests"
    },
    {
      "package": "affy",
      "role": "Suggests"
    },
    {
      "package": "PREDAsampledata",
      "role": "Suggests"
    },
    {
      "package": "Rmpi",
      "role": "Enhances"
    },
    {
      "package": "rsprng",
      "role": "Enhances"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.59.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.58.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "software",
    "copynumbervariation",
    "geneexpression",
    "genetics"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 452,
    "source": "https://www.bioconductor.org/packages/stats/bioc/PREDA"
  },
  "_mentions": 5,
  "_searchresults": 10,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/PREDA.html",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "analysesNames",
    "computeDatasetSignature",
    "DataForPREDA2dataframe",
    "DataForPREDA2GenomicAnnotationsForPREDA",
    "DataForPREDA2StatisticsForPREDA",
    "DataForPREDAMedianCenter",
    "eset2GenomicAnnotations",
    "genomePlot",
    "GenomicAnnotations2dataframe",
    "GenomicAnnotations2GenomicAnnotationsForPREDA",
    "GenomicAnnotations2reference_positions",
    "GenomicAnnotationsExtract",
    "GenomicAnnotationsFilter_neg",
    "GenomicAnnotationsFilter_pos",
    "GenomicAnnotationsForPREDA2dataframe",
    "GenomicAnnotationsForPREDA2GenomicAnnotations",
    "GenomicAnnotationsForPREDA2PREDAResults",
    "GenomicAnnotationsForPREDAFromfile",
    "GenomicAnnotationsFromdataframe",
    "GenomicAnnotationsFromfile",
    "GenomicAnnotationsFromLibrary",
    "GenomicAnnotationsSortAndCleanNA",
    "GenomicRegions2dataframe",
    "GenomicRegionsAnnotate",
    "GenomicRegionsChrNumber",
    "GenomicRegionsComparison",
    "GenomicRegionsCreateRegionsIds",
    "GenomicRegionsFilter_neg",
    "GenomicRegionsFilter_pos",
    "GenomicRegionsFindOverlap",
    "GenomicRegionsFromdataframe",
    "GenomicRegionsFromfile",
    "GenomicRegionsNumber",
    "GenomicRegionsSpan",
    "GenomicRegionsTotalSpan",
    "getStatisticByName",
    "MergeStatisticAnnotations2DataForPREDA",
    "PREDA_main",
    "PREDADataAndResults2dataframe",
    "PREDAResults2dataframe",
    "PREDAResults2GenomicRegions",
    "PREDAResults2GenomicRegionsSingle",
    "PREDAResults2PREDADataAndResults",
    "PREDAResultsGetObservedFlags",
    "preprocessingGE",
    "SODEGIR_GEstatistics",
    "SODEGIRpreprocessingGE",
    "StatisticsForPREDA2dataframe",
    "StatisticsForPREDAFilterColumns_neg",
    "StatisticsForPREDAFilterColumns_pos",
    "StatisticsForPREDAFromdataframe",
    "statisticsForPREDAfromEset",
    "StatisticsForPREDAFromfile"
  ],
  "_help": [
    {
      "page": "analysesNames",
      "title": "Get the names of the analyses in the from PREDA objects",
      "topics": [
        "analysesNames",
        "analysesNames,PREDAResults-method",
        "analysesNames,StatisticsForPREDA-method"
      ]
    },
    {
      "page": "computeDatasetSignature",
      "title": "Function to compute dataset signature for recurrent significant genomic regions",
      "topics": [
        "computeDatasetSignature",
        "computeDatasetSignature,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "DataForPREDA-class",
      "title": "Class \"DataForPREDA\" is used to manage all of the data required as input for PREDA analysis",
      "topics": [
        "DataForPREDA-class"
      ]
    },
    {
      "page": "DataForPREDA2dataframe",
      "title": "extract data and annotations as a dataframe",
      "topics": [
        "DataForPREDA2dataframe",
        "DataForPREDA2dataframe,DataForPREDA-method"
      ]
    },
    {
      "page": "DataForPREDA2GenomicAnnotationsForPREDA",
      "title": "extract a GenomicAnnotationsForPREDA object from a data DataForPREDA object",
      "topics": [
        "DataForPREDA2GenomicAnnotationsForPREDA",
        "DataForPREDA2GenomicAnnotationsForPREDA,DataForPREDA-method"
      ]
    },
    {
      "page": "DataForPREDA2StatisticsForPREDA",
      "title": "extract a StatisticsForPREDA object from a data DataForPREDA object",
      "topics": [
        "DataForPREDA2StatisticsForPREDA",
        "DataForPREDA2StatisticsForPREDA,DataForPREDA-method"
      ]
    },
    {
      "page": "DataForPREDAMedianCenter",
      "title": "Function to scale median value of DataForPREDA statistics to zero",
      "topics": [
        "DataForPREDAMedianCenter",
        "DataForPREDAMedianCenter,DataForPREDA-method"
      ]
    },
    {
      "page": "eset2GenomicAnnotations",
      "title": "Function building a GenomicAnnotations object on an ExpressionSet object",
      "topics": [
        "eset2GenomicAnnotations",
        "eset2GenomicAnnotations,ExpressionSet-method"
      ]
    },
    {
      "page": "genomePlot",
      "title": "draw a genome plot",
      "topics": [
        "genomePlot",
        "genomePlot,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "GenomicAnnotations-class",
      "title": "Class \"GenomicAnnotations\" to manage information about genomic features",
      "topics": [
        "GenomicAnnotations-class"
      ]
    },
    {
      "page": "GenomicAnnotations2dataframe",
      "title": "extracts annotations as a dataframe",
      "topics": [
        "GenomicAnnotations2dataframe",
        "GenomicAnnotations2dataframe,GenomicAnnotations-method",
        "GenomicAnnotations2dataframe,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "GenomicAnnotations2GenomicAnnotationsForPREDA",
      "title": "generate a GenomicAnnotationsForPREDA object from a GenomicAnnotations object",
      "topics": [
        "GenomicAnnotations2GenomicAnnotationsForPREDA",
        "GenomicAnnotations2GenomicAnnotationsForPREDA,GenomicAnnotations-method"
      ]
    },
    {
      "page": "GenomicAnnotations2reference_positions",
      "title": "extract reference positions from the GenomicAnnotations",
      "topics": [
        "GenomicAnnotations2reference_positions",
        "GenomicAnnotations2reference_positions,GenomicAnnotations-method"
      ]
    },
    {
      "page": "GenomicAnnotationsExtract",
      "title": "extract optional annotations for a specific region",
      "topics": [
        "GenomicAnnotationsExtract",
        "GenomicAnnotationsExtract,GenomicAnnotations-method"
      ]
    },
    {
      "page": "GenomicAnnotationsFilter_neg",
      "title": "filter annotations to remove selected chromosomes",
      "topics": [
        "GenomicAnnotationsFilter_neg",
        "GenomicAnnotationsFilter_neg,DataForPREDA-method",
        "GenomicAnnotationsFilter_neg,GenomicAnnotations-method",
        "GenomicAnnotationsFilter_neg,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "GenomicAnnotationsFilter_pos",
      "title": "filter annotations to keep selected chromosomes",
      "topics": [
        "GenomicAnnotationsFilter_pos",
        "GenomicAnnotationsFilter_pos,DataForPREDA-method",
        "GenomicAnnotationsFilter_pos,GenomicAnnotations-method",
        "GenomicAnnotationsFilter_pos,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "GenomicAnnotationsForPREDA-class",
      "title": "Class \"GenomicAnnotationsForPREDA\" GenomicAnnotations class with additional slot specifying the reference position for PREDA analysis",
      "topics": [
        "GenomicAnnotationsForPREDA-class"
      ]
    },
    {
      "page": "GenomicAnnotationsForPREDA2dataframe",
      "title": "extract annotations as a dataframe",
      "topics": [
        "GenomicAnnotationsForPREDA2dataframe",
        "GenomicAnnotationsForPREDA2dataframe,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "GenomicAnnotationsForPREDA2GenomicAnnotations",
      "title": "extract the GenomicAnnotations object from the GenomicAnnotationsForPREDA object",
      "topics": [
        "GenomicAnnotationsForPREDA2GenomicAnnotations",
        "GenomicAnnotationsForPREDA2GenomicAnnotations,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "GenomicAnnotationsForPREDA2PREDAResults",
      "title": "add PREDA results information to genomic annotatations creating a PREDAResults object",
      "topics": [
        "GenomicAnnotationsForPREDA2PREDAResults",
        "GenomicAnnotationsForPREDA2PREDAResults,GenomicAnnotationsForPREDA-method"
      ]
    },
    {
      "page": "GenomicAnnotationsForPREDAFromfile",
      "title": "Function to create a GenomicAnnotationsForPREDA object from a txt file",
      "topics": [
        "GenomicAnnotationsForPREDAFromfile"
      ]
    },
    {
      "page": "GenomicAnnotationsFromdataframe",
      "title": "Function to create a GenomiAnnotations object from a dataframe",
      "topics": [
        "GenomicAnnotationsFromdataframe"
      ]
    },
    {
      "page": "GenomicAnnotationsFromfile",
      "title": "Function to create a GenomiAnnotations object from a text file",
      "topics": [
        "GenomicAnnotationsFromfile"
      ]
    },
    {
      "page": "GenomicAnnotationsFromLibrary",
      "title": "Function extracting a GenomicAnnotations object from a Bioconductor annotation library",
      "topics": [
        "GenomicAnnotationsFromLibrary"
      ]
    },
    {
      "page": "GenomicAnnotationsSortAndCleanNA",
      "title": "sort annotations according to selected chromosomes and to remove genes containing any NA annotation field",
      "topics": [
        "GenomicAnnotationsSortAndCleanNA",
        "GenomicAnnotationsSortAndCleanNA,DataForPREDA-method",
        "GenomicAnnotationsSortAndCleanNA,GenomicAnnotations-method",
        "GenomicAnnotationsSortAndCleanNA,GenomicAnnotationsForPREDA-method",
        "GenomicAnnotationsSortAndCleanNA,PREDADataAndResults-method",
        "GenomicAnnotationsSortAndCleanNA,PREDAResults-method"
      ]
    },
    {
      "page": "GenomicRegions-class",
      "title": "Class \"GenomicRegions\" is used to manage information about genomic regions",
      "topics": [
        "GenomicRegions-class"
      ]
    },
    {
      "page": "GenomicRegions2dataframe",
      "title": "extract genomic regions information as a dataframe object",
      "topics": [
        "GenomicRegions2dataframe"
      ]
    },
    {
      "page": "GenomicRegionsAnnotate",
      "title": "extract annotations from a GenomicAnnotations object for a set of regions specified as a GenomicRegions object",
      "topics": [
        "GenomicRegionsAnnotate",
        "GenomicRegionsAnnotate,GenomicRegions,GenomicAnnotations-method"
      ]
    },
    {
      "page": "GenomicRegionsChrNumber",
      "title": "determine the number of chromosomes with genomic regions",
      "topics": [
        "GenomicRegionsChrNumber",
        "GenomicRegionsChrNumber,GenomicRegions-method"
      ]
    },
    {
      "page": "GenomicRegionsComparison",
      "title": "compare GenomicRegions objects to identify overlaps and differences",
      "topics": [
        "GenomicRegionsComparison",
        "GenomicRegionsComparison,GenomicRegions,GenomicRegions-method"
      ]
    },
    {
      "page": "GenomicRegionsCreateRegionsIds",
      "title": "generate unique ids for GenomicRegions objects",
      "topics": [
        "GenomicRegionsCreateRegionsIds",
        "GenomicRegionsCreateRegionsIds,GenomicRegions-method"
      ]
    },
    {
      "page": "GenomicRegionsFilter_neg",
      "title": "filter genomic regions to remove selected chromosomes",
      "topics": [
        "GenomicRegionsFilter_neg",
        "GenomicRegionsFilter_neg,GenomicRegions-method"
      ]
    },
    {
      "page": "GenomicRegionsFilter_pos",
      "title": "filter genomic regions to keep selected chromosomes",
      "topics": [
        "GenomicRegionsFilter_pos",
        "GenomicRegionsFilter_pos,GenomicRegions-method"
      ]
    },
    {
      "page": "GenomicRegionsFindOverlap",
      "title": "Function to find overlap between GenomicRegions objects",
      "topics": [
        "GenomicRegionsFindOverlap"
      ]
    },
    {
      "page": "GenomicRegionsFromdataframe",
      "title": "Function to create a GenomiRegions object from a dataframe",
      "topics": [
        "GenomicRegionsFromdataframe"
      ]
    },
    {
      "page": "GenomicRegionsFromfile",
      "title": "Function to create a GenomiRegions object from a text file",
      "topics": [
        "GenomicRegionsFromfile"
      ]
    },
    {
      "page": "GenomicRegionsNumber",
      "title": "determine the number of genomic regions",
      "topics": [
        "GenomicRegionsNumber",
        "GenomicRegionsNumber,GenomicRegions-method"
      ]
    },
    {
      "page": "GenomicRegionsSpan",
      "title": "determine the span of each genomic region",
      "topics": [
        "GenomicRegionsSpan",
        "GenomicRegionsSpan,GenomicRegions-method"
      ]
    },
    {
      "page": "GenomicRegionsTotalSpan",
      "title": "determine the total span of genomic regions",
      "topics": [
        "GenomicRegionsTotalSpan",
        "GenomicRegionsTotalSpan,GenomicRegions-method"
      ]
    },
    {
      "page": "getStatisticByName",
      "title": "extract data for individual analyses using the analysis name",
      "topics": [
        "getStatisticByName",
        "getStatisticByName,StatisticsForPREDA-method"
      ]
    },
    {
      "page": "MergeStatisticAnnotations2DataForPREDA",
      "title": "Merge a StatisticsForPREDA and a GenomicAnnotationsForPREDA object into a DataForPREDA object.",
      "topics": [
        "MergeStatisticAnnotations2DataForPREDA"
      ]
    },
    {
      "page": "PREDA_main",
      "title": "function performing the core of PREDA analysis",
      "topics": [
        "PREDA_main"
      ]
    },
    {
      "page": "PREDADataAndResults-class",
      "title": "Class \"PREDADataAndResults\" is used to manage the PREDA analysis output",
      "topics": [
        "PREDADataAndResults-class"
      ]
    },
    {
      "page": "PREDADataAndResults2dataframe",
      "title": "extract data and annotations as a dataframe with probeids as rownames",
      "topics": [
        "PREDADataAndResults2dataframe",
        "PREDADataAndResults2dataframe,PREDADataAndResults-method"
      ]
    },
    {
      "page": "PREDAResults-class",
      "title": "Class \"PREDAResults\" ~is used to manage the PREDA analysis output",
      "topics": [
        "PREDAResults-class"
      ]
    },
    {
      "page": "PREDAResults2dataframe",
      "title": "extact preda results statistics as a data frame object",
      "topics": [
        "PREDAResults2dataframe",
        "PREDAResults2dataframe,PREDAResults-method"
      ]
    },
    {
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