{
  "_id": "6a1ac0c01d7bb097a09d719d",
  "Package": "PAST",
  "Type": "Package",
  "Title": "Pathway Association Study Tool (PAST)",
  "Version": "1.29.0",
  "Authors@R": "c(person(\"Thrash\", \"Adam\", email = \"thrash@igbb.msstate.edu\",\nrole = c(\"cre\", \"aut\")), person(\"DeOrnellis\", \"Mason\", role = c(\"aut\")))",
  "Description": "PAST takes GWAS output and assigns SNPs to genes, uses\nthose genes to find pathways associated with the genes, and\nplots pathways based on significance. Implements methods for\nreading GWAS input data, finding genes associated with SNPs,\ncalculating enrichment score and significance of pathways, and\nplotting pathways.",
  "License": "GPL (>=3) + file LICENSE",
  "Encoding": "UTF-8",
  "VignetteBuilder": "knitr",
  "RoxygenNote": "7.1.0",
  "URL": "https://github.com/IGBB/past",
  "BugReports": "https://github.com/IGBB/past/issues",
  "biocViews": "Pathways, GeneSetEnrichment",
  "Config/pak/sysreqs": "make libbz2-dev libicu-dev liblzma-dev libxml2-dev\nlibssl-dev xz-utils zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:50:17 UTC",
  "RemoteUrl": "https://github.com/bioc/PAST",
  "RemoteRef": "HEAD",
  "RemoteSha": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 07:17:15 UTC",
    "User": "root"
  },
  "Author": "Thrash Adam [cre, aut],\nDeOrnellis Mason [aut]",
  "Maintainer": "Thrash Adam <thrash@igbb.msstate.edu>",
  "MD5sum": "23ff50b2e1afd1b129ea5f4d78765d79",
  "_user": "bioc",
  "_type": "src",
  "_file": "PAST_1.29.0.tar.gz",
  "_fileid": "934df55d1c2a872e5f2aaaf490f96d2cb463eeaa914cca90f53c74fe16fcfeab",
  "_filesize": 1069296,
  "_sha256": "934df55d1c2a872e5f2aaaf490f96d2cb463eeaa914cca90f53c74fe16fcfeab",
  "_created": "2026-05-30T07:17:15.000Z",
  "_published": "2026-05-30T10:49:36.932Z",
  "_jobs": [
    {
      "job": 78632950204,
      "time": 185,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7306419340"
    },
    {
      "job": 78632950263,
      "time": 547,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7306458831"
    },
    {
      "job": 78632950203,
      "time": 482,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7306450994"
    },
    {
      "job": 78632950259,
      "time": 293,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7307510503"
    },
    {
      "job": 78632950262,
      "time": 317,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7307518685"
    },
    {
      "job": 78632653836,
      "time": 332,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7306397691"
    },
    {
      "job": 78632950198,
      "time": 160,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7306416492"
    },
    {
      "job": 78632950258,
      "time": 416,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7306443537"
    },
    {
      "job": 78632950265,
      "time": 427,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7306444677"
    },
    {
      "job": 78632950255,
      "time": 461,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7306448573"
    }
  ],
  "_bioccheck": {
    "error": 0,
    "warning": 1,
    "note": 9
  },
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/PAST",
  "_commit": {
    "id": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777380617
  },
  "_maintainer": {
    "name": "Thrash Adam",
    "email": "thrash@igbb.msstate.edu",
    "login": "adamthrash",
    "description": "",
    "uuid": 1187214
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 4.0",
      "role": "Depends"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    },
    {
      "package": "dplyr",
      "role": "Imports"
    },
    {
      "package": "rlang",
      "role": "Imports"
    },
    {
      "package": "iterators",
      "role": "Imports"
    },
    {
      "package": "parallel",
      "role": "Imports"
    },
    {
      "package": "foreach",
      "role": "Imports"
    },
    {
      "package": "doParallel",
      "role": "Imports"
    },
    {
      "package": "qvalue",
      "role": "Imports"
    },
    {
      "package": "rtracklayer",
      "role": "Imports"
    },
    {
      "package": "ggplot2",
      "role": "Imports"
    },
    {
      "package": "GenomicRanges",
      "role": "Imports"
    },
    {
      "package": "S4Vectors",
      "role": "Imports"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.29.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.28.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "pathways",
    "genesetenrichment"
  ],
  "_stars": 5,
  "_contributors": [
    {
      "user": "adamthrash",
      "count": 15,
      "uuid": 1187214
    }
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 376,
    "source": "https://www.bioconductor.org/packages/stats/bioc/PAST"
  },
  "_mentions": 2336,
  "_devurl": "https://github.com/igbb/past",
  "_searchresults": 6,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/PAST.html",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "assign_SNPs_to_genes",
    "find_pathway_significance",
    "load_GWAS_data",
    "load_LD",
    "plot_pathways"
  ],
  "_help": [
    {
      "page": "assign_chunk",
      "title": "Assign SNPs in a chunk to genes",
      "topics": [
        "assign_chunk"
      ]
    },
    {
      "page": "assign_SNPs_to_genes",
      "title": "Assign SNPs to genes",
      "topics": [
        "assign_SNPs_to_genes"
      ]
    },
    {
      "page": "determine_linkage",
      "title": "Determine Linkage",
      "topics": [
        "determine_linkage"
      ]
    },
    {
      "page": "find_pathway_significance",
      "title": "Find Pathway Significance",
      "topics": [
        "find_pathway_significance"
      ]
    },
    {
      "page": "find_representative_SNP",
      "title": "Find representative SNP for a chunk of SNPs",
      "topics": [
        "find_representative_SNP"
      ]
    },
    {
      "page": "find_representative_SNP_gene_pairing",
      "title": "Find the SNP-gene assignment that represents SNPs assigned to a gene",
      "topics": [
        "find_representative_SNP_gene_pairing"
      ]
    },
    {
      "page": "load_GWAS_data",
      "title": "Load GWAS data",
      "topics": [
        "load_GWAS_data"
      ]
    },
    {
      "page": "load_LD",
      "title": "Load Linkage Disequilibrium",
      "topics": [
        "load_LD"
      ]
    },
    {
      "page": "plot_pathways",
      "title": "Plot Rugplots for Selected Pathways",
      "topics": [
        "plot_pathways"
      ]
    }
  ],
  "_readme": "https://github.com/bioc/PAST/raw/HEAD/README.md",
  "_rundeps": [
    "abind",
    "askpass",
    "BH",
    "Biobase",
    "BiocBaseUtils",
    "BiocGenerics",
    "BiocIO",
    "BiocParallel",
    "Biostrings",
    "bitops",
    "cigarillo",
    "cli",
    "codetools",
    "cpp11",
    "crayon",
    "curl",
    "DelayedArray",
    "doParallel",
    "dplyr",
    "farver",
    "foreach",
    "formatR",
    "futile.logger",
    "futile.options",
    "generics",
    "GenomicAlignments",
    "GenomicRanges",
    "ggplot2",
    "glue",
    "gtable",
    "httr",
    "IRanges",
    "isoband",
    "iterators",
    "jsonlite",
    "labeling",
    "lambda.r",
    "lattice",
    "lifecycle",
    "magrittr",
    "Matrix",
    "MatrixGenerics",
    "matrixStats",
    "mime",
    "openssl",
    "pillar",
    "pkgconfig",
    "plyr",
    "qvalue",
    "R6",
    "RColorBrewer",
    "Rcpp",
    "RCurl",
    "reshape2",
    "restfulr",
    "Rhtslib",
    "rjson",
    "rlang",
    "Rsamtools",
    "rtracklayer",
    "S4Arrays",
    "S4Vectors",
    "S7",
    "scales",
    "Seqinfo",
    "snow",
    "SparseArray",
    "stringi",
    "stringr",
    "SummarizedExperiment",
    "sys",
    "tibble",
    "tidyselect",
    "utf8",
    "vctrs",
    "viridisLite",
    "withr",
    "XML",
    "XVector",
    "yaml"
  ],
  "_vignettes": [
    {
      "source": "past.Rmd",
      "filename": "past.html",
      "title": "PAST",
      "author": "Adam Thrash",
      "engine": "knitr::rmarkdown",
      "headings": [
        "PAST",
        "Loading GWAS Data",
        "Loading LD Data",
        "Assigning SNPs to Genes",
        "Finding Pathway Significance",
        "Plotting Selected Pathways",
        "References"
      ],
      "created": "2019-03-01 16:49:10",
      "modified": "2020-03-11 19:23:19",
      "commits": 9
    }
  ],
  "_score": 5.698970004336019,
  "_indexed": true,
  "_nocasepkg": "past",
  "_universes": [
    "bioc",
    "adamthrash",
    "igbb"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.29.0",
      "date": "2026-05-30T07:21:31.000Z",
      "distro": "noble",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "3c8b17ae4f10f89031e5d7ec0a27a7d76b2eb8a9ac03430f8b2ee59c5b8389d9",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.29.0",
      "date": "2026-05-30T07:20:39.000Z",
      "distro": "noble",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "68d245aa8394139ff0e4d13952637ef7603606e07bc084aa79c33387c6897de6",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.29.0",
      "date": "2026-05-30T10:24:00.000Z",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "b5b6f3c19ea4d17ddaa7f104ebb394fd5584bddbf2f7d0f05cf9b4363a1b21a4",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.29.0",
      "date": "2026-05-30T10:25:27.000Z",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "67565a9ce87a986fa4728d563f232a41e067f941ee613d947e489fb4b413108c",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.29.0",
      "date": "2026-05-30T07:20:30.000Z",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "c3599c7641900776374c5bb802ed777d4e59153fa5c587bf912b110e31c50df1",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.29.0",
      "date": "2026-05-30T07:19:53.000Z",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "d90a78cc30de643b92fe5a01675b788e06cb3280daa482626682453a77bd52ed",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.29.0",
      "date": "2026-05-30T07:19:28.000Z",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "8dc5c0e062e5e404147358ce18d4828cc7e08c0a90d9d6a201be4c814c081245",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.29.0",
      "date": "2026-05-30T07:19:11.000Z",
      "commit": "b3a609543dc3cc58661b0b707e8a861b37a945b7",
      "fileid": "606103c95c7607de49eba7d614c1dfd59b21d88798c4d45b69ada34edd5ccaea",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/26677754237"
    }
  ]
}