{
  "_id": "6abe196099f7aa8c6aa51ffe",
  "Package": "MetaPathNet",
  "Title": "KEGG-Based Metabolic and Signaling Network Analysis for Systems\nBiology",
  "Version": "0.99.5",
  "Authors@R": "c(\nperson(\n\"Zhaojie\", \"Wang\",\nemail = \"zhaojie.wang@cnrs.fr\",\nrole = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0009-0009-7191-2107\")\n),\nperson(\"Francesc\", \"Puig-Castellvi\", role = \"aut\"),\nperson(\"Manyi\", \"Jia\", role = \"aut\"),\nperson(\"Marc-Emmanuel\", \"Dumas\", role = c(\"aut\", \"ths\")),\nperson(\"Centre National de la Recherche Scientifique\", role = \"fnd\"),\nperson(\"Imperial College London\", role = \"fnd\"),\nperson(\"French National Research Agency\", role = \"fnd\")\n)",
  "Description": "Provides tools to construct KEGG-based metabolic and\nsignaling networks as edge lists for single-organism or\ncross-species analyses. The package supports identifier\nmapping, shortest-path and topology analyses, community\ndetection, permutation testing, pathway over-representation\nanalysis, and node annotation for host-microbiome studies. It\nalso provides network visualisation in R and Cytoscape and\nsupports extension of KEGG-based networks through additional\nreaction resources and user-defined reactions.",
  "SystemRequirements": "Cytoscape (>= 3.9.0) for Cytoscape-based\nvisualisation functions",
  "biocViews": "Network, Pathways, KEGG, SystemsBiology, Classification,\nMicrobiome",
  "License": "MIT + file LICENSE",
  "Encoding": "UTF-8",
  "Roxygen": "list(markdown = TRUE)",
  "VignetteBuilder": "knitr",
  "URL": "https://github.com/zhaojie-wang/MetaPathNet",
  "BugReports": "https://github.com/zhaojie-wang/MetaPathNet/issues",
  "Config/roxygen2/version": "8.0.0",
  "Config/pak/sysreqs": "cmake libfontconfig1-dev libfreetype6-dev\nlibglpk-dev make libbz2-dev libicu-dev liblzma-dev libpng-dev\nlibuv1-dev libxml2-dev libssl-dev python3 xz-utils libzmq3-dev\nzlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-07-28 19:59:42 UTC",
  "RemoteUrl": "https://github.com/bioc/MetaPathNet",
  "RemoteRef": "HEAD",
  "RemoteSha": "fdaae4de76d724123116933a9d97d8684b9bebf1",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-10-01 08:15:08 UTC",
    "User": "root"
  },
  "Author": "Zhaojie Wang [aut, cre] (ORCID:\n<https://orcid.org/0009-0009-7191-2107>),\nFrancesc Puig-Castellvi [aut],\nManyi Jia [aut],\nMarc-Emmanuel Dumas [aut, ths],\nCentre National de la Recherche Scientifique [fnd],\nImperial College London [fnd],\nFrench National Research Agency [fnd]",
  "Maintainer": "Zhaojie Wang <zhaojie.wang@cnrs.fr>",
  "_user": "bioc",
  "_type": "src",
  "_file": "MetaPathNet_0.99.5.tar.gz",
  "_fileid": "https://r2.ropensci.org/3cf7d6e68757d4d52c4d405ecc11b79b0b25893f6771839dc7765870102996f2",
  "_filesize": 1060970,
  "_sha256": "3cf7d6e68757d4d52c4d405ecc11b79b0b25893f6771839dc7765870102996f2",
  "_expires": "2027-01-09T08:27:09.000Z",
  "_created": "2026-10-01T08:15:08.000Z",
  "_published": "2026-10-01T08:27:12.397Z",
  "_bioccheck": {
    "error": 0,
    "warning": 0,
    "note": 8
  },
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153",
  "_status": "failure",
  "_upstream": "https://github.com/bioc/MetaPathNet",
  "_commit": {
    "id": "fdaae4de76d724123116933a9d97d8684b9bebf1",
    "author": "Zhaojie Wang <zhaojie.wang@cnrs.fr>",
    "committer": "Zhaojie Wang <zhaojie.wang@cnrs.fr>",
    "message": "Address reviewer API and enrichment plot comments\n",
    "time": 1785268782
  },
  "_maintainer": {
    "name": "Zhaojie Wang",
    "email": "zhaojie.wang@cnrs.fr",
    "login": "zhaojie-wang",
    "description": "",
    "uuid": 280365406,
    "orcid": "0009-0009-7191-2107"
  },
  "_distro": "resolute",
  "_jobs": [
    {
      "job": 110280980439,
      "time": 217,
      "config": "bioc-checks",
      "r": "4.6.1",
      "check": "NOTE",
      "artifact": "11149181222"
    },
    {
      "job": 110280980360,
      "time": 351,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "11149415954"
    },
    {
      "job": 110280980341,
      "time": 463,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "WARNING",
      "artifact": "11149456046"
    },
    {
      "job": 110280980370,
      "time": 349,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "11148744367"
    },
    {
      "job": 110280980376,
      "time": 443,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "WARNING",
      "artifact": "11149191912"
    },
    {
      "job": 110278555152,
      "time": 442,
      "config": "source",
      "r": "4.6.1",
      "check": "ERROR",
      "artifact": "11149420171"
    },
    {
      "job": 110280980436,
      "time": 189,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "11149076809"
    },
    {
      "job": 110280980380,
      "time": 316,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "11148593970"
    },
    {
      "job": 110280980496,
      "time": 307,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "11149037532"
    },
    {
      "job": 110280980425,
      "time": 310,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "WARNING",
      "artifact": "11148917801"
    }
  ],
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 4.5.0",
      "role": "Depends"
    },
    {
      "package": "igraph",
      "role": "Imports"
    },
    {
      "package": "httr",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    },
    {
      "package": "RCurl",
      "role": "Imports"
    },
    {
      "package": "RCy3",
      "role": "Imports"
    },
    {
      "package": "tidygraph",
      "role": "Imports"
    },
    {
      "package": "ggraph",
      "role": "Imports"
    },
    {
      "package": "dplyr",
      "role": "Imports"
    },
    {
      "package": "KEGGREST",
      "role": "Imports"
    },
    {
      "package": "KEGGgraph",
      "role": "Imports"
    },
    {
      "package": "graph",
      "role": "Imports"
    },
    {
      "package": "mygene",
      "role": "Imports"
    },
    {
      "package": "ggplot2",
      "role": "Imports"
    },
    {
      "package": "rlang",
      "role": "Imports"
    },
    {
      "package": "curl",
      "role": "Imports"
    },
    {
      "package": "jsonlite",
      "role": "Imports"
    },
    {
      "package": "webchem",
      "role": "Imports"
    },
    {
      "package": "grDevices",
      "role": "Imports"
    },
    {
      "package": "grid",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    },
    {
      "package": "BiocStyle",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2026-18",
      "n": 6
    },
    {
      "week": "2026-24",
      "n": 1
    },
    {
      "week": "2026-29",
      "n": 3
    },
    {
      "week": "2026-31",
      "n": 1
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "0.99.5",
      "bioc": "3.24"
    }
  ],
  "_topics": [
    "network",
    "pathways",
    "kegg",
    "systemsbiology",
    "classification",
    "microbiome"
  ],
  "_stars": 2,
  "_contributors": [
    {
      "user": "zhaojie-wang",
      "count": 12,
      "uuid": 280365406
    }
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "followers": 471,
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 597,
    "source": "https://www.bioconductor.org/packages/stats/bioc/MetaPathNet"
  },
  "_devurl": "https://github.com/zhaojie-wang/metapathnet",
  "_searchresults": 0,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/manual.pdf",
    "extra/MetaPathNet.html",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "LICENSE"
  ],
  "_homeurl": "https://github.com/zhaojie-wang/metapathnet",
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "addCustomReaction",
    "annotateKoClass",
    "annotateOrigin",
    "buildCompoundEgoNetwork",
    "buildCrossSpeciesNetwork",
    "buildEgoNetwork",
    "buildKeggNetwork",
    "clusterNetwork",
    "combineNetworks",
    "convertGene",
    "enrichmentDotPlot",
    "enrichPathway",
    "findKeggIDs",
    "findMappedNodes",
    "findShortestPaths",
    "getPathIDs",
    "mapReaction",
    "networkDistances",
    "networkSimilarity",
    "permutePaths",
    "removeDrugs",
    "removeNetworkNodes",
    "replaceNode",
    "suggestEntities",
    "viewClusterCy",
    "viewNetworkCy",
    "viewNetworkR"
  ],
  "_datasets": [
    {
      "name": "MetaPathNet_example_network",
      "title": "Example tryptophan-related MetaPathNet network",
      "object": "MetaPathNet_example_network",
      "file": "MetaPathNet_example_network.rda",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [
        "source",
        "target",
        "interaction_type"
      ],
      "rows": 1769,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "addCustomReaction",
      "title": "Build MetaPathNet-style edges from user-defined reactions",
      "topics": [
        "addCustomReaction"
      ]
    },
    {
      "page": "annotateKoClass",
      "title": "Annotate KO functional class (metabolic vs signalling)",
      "topics": [
        "annotateKoClass"
      ]
    },
    {
      "page": "annotateOrigin",
      "title": "Annotate KO Origin (Host vs Bacteria) and Optionally Export to Cytoscape",
      "topics": [
        "annotateOrigin"
      ]
    },
    {
      "page": "buildCompoundEgoNetwork",
      "title": "Build compound-centred ego subnetworks across KEGG organisms",
      "topics": [
        "buildCompoundEgoNetwork"
      ]
    },
    {
      "page": "buildCrossSpeciesNetwork",
      "title": "Build Cross-Species MetaPathNet Network",
      "topics": [
        "buildCrossSpeciesNetwork"
      ]
    },
    {
      "page": "buildEgoNetwork",
      "title": "Extract an Ego Subnetwork from a Metabolic / Signalling Network",
      "topics": [
        "buildEgoNetwork"
      ]
    },
    {
      "page": "buildKeggNetwork",
      "title": "Build KEGG Metabolic and Signaling Network",
      "topics": [
        "buildKeggNetwork"
      ]
    },
    {
      "page": "clusterNetwork",
      "title": "Community Detection in KEGG-Derived Networks",
      "topics": [
        "clusterNetwork"
      ]
    },
    {
      "page": "combineNetworks",
      "title": "Merge Multiple MetaPathNet-Style Networks",
      "topics": [
        "combineNetworks"
      ]
    },
    {
      "page": "convertGene",
      "title": "Convert Ensembl or Entrez Gene IDs to KEGG Gene IDs and KO Terms",
      "topics": [
        "convertGene"
      ]
    },
    {
      "page": "enrichmentDotPlot",
      "title": "Create a Dot Plot of Pathway Enrichment Results",
      "topics": [
        "enrichmentDotPlot"
      ]
    },
    {
      "page": "enrichPathway",
      "title": "Pathway Enrichment Analysis on KEGG-Based Node Sets",
      "topics": [
        "enrichPathway"
      ]
    },
    {
      "page": "findKeggIDs",
      "title": "Find KEGG Identifiers for Compounds, Organisms, and KO Terms",
      "topics": [
        "findKeggIDs"
      ]
    },
    {
      "page": "findMappedNodes",
      "title": "Map User-Supplied Nodes to a Network",
      "topics": [
        "findMappedNodes"
      ]
    },
    {
      "page": "findShortestPaths",
      "title": "Identify Shortest Paths Between Node Sets in a KEGG-Derived Network",
      "topics": [
        "findShortestPaths"
      ]
    },
    {
      "page": "getPathIDs",
      "title": "Retrieve and Classify Organism-Specific KEGG Pathways",
      "topics": [
        "getPathIDs"
      ]
    },
    {
      "page": "mapReaction",
      "title": "Map reaction IDs to MetaPathNet-style networks",
      "topics": [
        "mapReaction"
      ]
    },
    {
      "page": "MetaPathNet_example_network",
      "title": "Example tryptophan-related MetaPathNet network",
      "topics": [
        "MetaPathNet_example_network"
      ]
    },
    {
      "page": "networkDistances",
      "title": "Calculate Shortest-Path Distances Between Node Sets in a KEGG-Based Network",
      "topics": [
        "networkDistances"
      ]
    },
    {
      "page": "networkSimilarity",
      "title": "Compare KEGG-Based Networks via Jaccard Similarity",
      "topics": [
        "networkSimilarity"
      ]
    },
    {
      "page": "permutePaths",
      "title": "Permutation Test of Shortest-Path Structure Between Node Sets",
      "topics": [
        "permutePaths"
      ]
    },
    {
      "page": "removeDrugs",
      "title": "Remove Drug Nodes from a Network Matrix",
      "topics": [
        "removeDrugs"
      ]
    },
    {
      "page": "removeNetworkNodes",
      "title": "Remove Specified Nodes from a Network Matrix",
      "topics": [
        "removeNetworkNodes"
      ]
    },
    {
      "page": "replaceNode",
      "title": "Replace Nodes in a Network Table",
      "topics": [
        "replaceNode"
      ]
    },
    {
      "page": "suggestEntities",
      "title": "Suggest Candidate Prokaryotic Organisms or KOs from KEGG Identifiers",
      "topics": [
        "suggestEntities"
      ]
    },
    {
      "page": "viewClusterCy",
      "title": "Visualise Clustered MetaPathNet Networks in Cytoscape",
      "topics": [
        "viewClusterCy"
      ]
    },
    {
      "page": "viewNetworkCy",
      "title": "Visualize a KEGG-Derived Network in Cytoscape via RCy3",
      "topics": [
        "viewNetworkCy"
      ]
    },
    {
      "page": "viewNetworkR",
      "title": "Visualise a KEGG-Based Network Matrix in R",
      "topics": [
        "viewNetworkR"
      ]
    }
  ],
  "_rundeps": [
    "AnnotationDbi",
    "askpass",
    "backports",
    "base64enc",
    "base64url",
    "BH",
    "Biobase",
    "BiocBaseUtils",
    "BiocFileCache",
    "BiocGenerics",
    "BiocIO",
    "BiocParallel",
    "biomaRt",
    "Biostrings",
    "bit",
    "bit64",
    "bitops",
    "blob",
    "bslib",
    "cachem",
    "caTools",
    "checkmate",
    "chron",
    "cigarillo",
    "cli",
    "cluster",
    "codetools",
    "colorspace",
    "cpp11",
    "crayon",
    "curl",
    "data.table",
    "data.tree",
    "DBI",
    "dbplyr",
    "digest",
    "dplyr",
    "evaluate",
    "farver",
    "fastmap",
    "filelock",
    "fontawesome",
    "foreign",
    "formatR",
    "Formula",
    "fs",
    "futile.logger",
    "futile.options",
    "generics",
    "GenomeInfoDb",
    "GenomicAlignments",
    "GenomicFeatures",
    "GenomicRanges",
    "ggforce",
    "ggplot2",
    "ggraph",
    "ggrepel",
    "glue",
    "gplots",
    "graph",
    "graphlayouts",
    "gridExtra",
    "gsubfn",
    "gtable",
    "gtools",
    "highr",
    "Hmisc",
    "hms",
    "htmlTable",
    "htmltools",
    "htmlwidgets",
    "httr",
    "httr2",
    "igraph",
    "IRanges",
    "IRdisplay",
    "IRkernel",
    "isoband",
    "jquerylib",
    "jsonlite",
    "KEGGgraph",
    "KEGGREST",
    "KernSmooth",
    "knitr",
    "labeling",
    "lambda.r",
    "lattice",
    "lifecycle",
    "magrittr",
    "MASS",
    "Matrix",
    "memoise",
    "mime",
    "mygene",
    "nnet",
    "openssl",
    "pbdZMQ",
    "pillar",
    "pkgconfig",
    "plyr",
    "png",
    "polyclip",
    "prettyunits",
    "progress",
    "proto",
    "purrr",
    "R6",
    "rappdirs",
    "RColorBrewer",
    "Rcpp",
    "RcppArmadillo",
    "RCurl",
    "RCy3",
    "repr",
    "restfulr",
    "Rgraphviz",
    "Rhtslib",
    "rjson",
    "RJSONIO",
    "rlang",
    "rmarkdown",
    "rpart",
    "Rsamtools",
    "RSQLite",
    "rstudioapi",
    "rtracklayer",
    "rvest",
    "S4Vectors",
    "S7",
    "sass",
    "scales",
    "selectr",
    "Seqinfo",
    "snow",
    "sqldf",
    "stringi",
    "stringr",
    "sys",
    "systemfonts",
    "tibble",
    "tidygraph",
    "tidyr",
    "tidyselect",
    "tinytex",
    "tweenr",
    "txdbmaker",
    "UCSC.utils",
    "utf8",
    "uuid",
    "vctrs",
    "viridis",
    "viridisLite",
    "webchem",
    "withr",
    "xfun",
    "XML",
    "xml2",
    "XVector",
    "yaml"
  ],
  "_score": 2.9030899869919438,
  "_indexed": true,
  "_nocasepkg": "metapathnet",
  "_universes": [
    "bioc",
    "zhaojie-wang"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.99.5",
      "date": "2026-10-01T08:19:20.000Z",
      "distro": "resolute",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/e44f10db3b1847e7831e214dbaf6dc07fad9818c033e4aaa33ee436271e47bd3",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "0.99.5",
      "date": "2026-10-01T08:20:38.000Z",
      "distro": "resolute",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/a579dd68bc0abd25f754de2b0989a5fefc27f04c802890d33923f55b470e39ff",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.99.5",
      "date": "2026-10-01T08:23:43.000Z",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/67c8070b13316955ecf57ed8baae7ddd9e9e250290dd49bb5e225fef0b559de9",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "0.99.5",
      "date": "2026-10-01T08:20:08.000Z",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/d3ed71a45f9593295635ffda86e9e2948755d5d41f8739b936408134ba12e64d",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.99.5",
      "date": "2026-10-01T08:19:04.000Z",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/bb46eab70bfde27326bc9ccb0ef15c94c103a55dc35019830a7dc1df9749a56b",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.99.5",
      "date": "2026-10-01T08:17:23.000Z",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/d4d2b92ee571040e432da5f4397b4a217b57541f73d2da7dbe80f519ac6857cf",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.99.5",
      "date": "2026-10-01T08:17:27.000Z",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/7f084d654eea9fdf815603c76575fc32c13e3a013df77abc08d7ed4b79192ca7",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "0.99.5",
      "date": "2026-10-01T08:17:19.000Z",
      "commit": "fdaae4de76d724123116933a9d97d8684b9bebf1",
      "fileid": "https://r2.ropensci.org/4f21aaaf67f771ab422c8015fa9fedea23a48632ad7f057b0dfef342a4988327",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/36834468153"
    }
  ]
}