{ "_id": "6a1d278b1d7bb097a0a38251", "Package": "IFAA", "Title": "Robust Inference for Absolute Abundance in Microbiome Analysis", "Version": "1.15.0", "Authors@R": "c(person(given = \"Quran\",\nfamily = \"Wu\",\nrole = c(\"aut\"),\nemail = \"wuquran@ufl.edu\"),\nperson(given = \"Zhigang\",\nfamily = \"Li\",\nrole = c(\"aut\", \"cre\"),\nemail = \"lzg2151@gmail.com\")\n)", "Description": "This package offers a robust approach to make inference on\nthe association of covariates with the absolute abundance (AA)\nof microbiome in an ecosystem. It can be also directly applied\nto relative abundance (RA) data to make inference on AA because\nthe ratio of two RA is equal to the ratio of their AA. This\nalgorithm can estimate and test the associations of interest\nwhile adjusting for potential confounders. The estimates of\nthis method have easy interpretation like a typical regression\nanalysis. High-dimensional covariates are handled with\nregularization and it is implemented by parallel computing.\nFalse discovery rate is automatically controlled by this\napproach. Zeros do not need to be imputed by a positive value\nfor the analysis. The IFAA package also offers the 'MZILN'\nfunction for estimating and testing associations of abundance\nratios with covariates.", "License": "GPL-2", "Encoding": "UTF-8", "URL": "https://pubmed.ncbi.nlm.nih.gov/35241863/,\nhttps://pubmed.ncbi.nlm.nih.gov/30923584/,\nhttps://github.com/quranwu/IFAA", "BugReports": "https://github.com/quranwu/IFAA/issues", "RoxygenNote": "7.3.1", "biocViews": "Software, Technology, Sequencing, Microbiome, Regression", "RdMacros": "mathjaxr", "VignetteBuilder": "knitr", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-30 07:56:40 UTC", "User": "root" }, "Config/pak/sysreqs": "cmake make libicu-dev libuv1-dev libssl-dev\nlibx11-dev zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:59:29 UTC", "RemoteUrl": "https://github.com/bioc/IFAA", "RemoteRef": "HEAD", "RemoteSha": "ca971399a54408343cea32ff027f36f1fcf3b39e", "Author": "Quran Wu [aut],\nZhigang Li [aut, cre]", "Maintainer": "Zhigang Li ", "MD5sum": 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