{
  "_id": "6ab22fe23d719c1f8408a051",
  "Package": "HybridMTest",
  "Type": "Package",
  "Title": "Hybrid Multiple Testing",
  "Version": "1.57.0",
  "Date": "2011-06-14",
  "Author": "Stan Pounds <stanley.pounds@stjude.org>, Demba Fofana\n<demba.fofana@stjude.org>",
  "Maintainer": "Demba Fofana <demba.fofana@stjude.org>",
  "Description": "Performs hybrid multiple testing that incorporates method\nselection and assumption evaluations into the analysis using\nempirical Bayes probability (EBP) estimates obtained by\nGrenander density estimation. For instance, for 3-group\ncomparison analysis, Hybrid Multiple testing considers EBPs as\nweighted EBPs between F-test and H-test with EBPs from Shapiro\nWilk test of normality as weigth. Instead of just using EBPs\nfrom F-test only or using H-test only, this methodology\ncombines both types of EBPs through EBPs from Shapiro Wilk test\nof normality. This methodology uses then the law of total EBPs.",
  "License": "GPL Version 2 or later",
  "LazyLoad": "yes",
  "Packaged": {
    "Date": "2026-09-22 07:31:06 UTC",
    "User": "root"
  },
  "biocViews": "GeneExpression, Genetics, Microarray",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:36:21 UTC",
  "RemoteUrl": "https://github.com/bioc/HybridMTest",
  "RemoteRef": "HEAD",
  "RemoteSha": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
  "NeedsCompilation": "no",
  "_user": "bioc",
  "_type": "src",
  "_file": "HybridMTest_1.57.0.tar.gz",
  "_fileid": "https://r2.ropensci.org/c1193a1fa9b5e86e4649099daedd2a8f9d9dd611b2f2c482b07be57023754045",
  "_filesize": 293974,
  "_sha256": "c1193a1fa9b5e86e4649099daedd2a8f9d9dd611b2f2c482b07be57023754045",
  "_expires": "2026-12-31T07:36:00.000Z",
  "_created": "2026-09-22T07:31:06.000Z",
  "_published": "2026-09-22T07:36:02.652Z",
  "_bioccheck": {
    "error": 1,
    "warning": 3,
    "note": 12
  },
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284",
  "_status": "success",
  "_upstream": "https://github.com/bioc/HybridMTest",
  "_commit": {
    "id": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777379781
  },
  "_maintainer": {
    "name": "Demba Fofana",
    "email": "demba.fofana@stjude.org"
  },
  "_distro": "resolute",
  "_jobs": [
    {
      "job": 106655572724,
      "time": 122,
      "config": "bioc-checks",
      "r": "4.6.1",
      "check": "ERROR",
      "artifact": "10681678328"
    },
    {
      "job": 106655572847,
      "time": 230,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "10682236772"
    },
    {
      "job": 106655572830,
      "time": 189,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "NOTE",
      "artifact": "10682705938"
    },
    {
      "job": 106655572690,
      "time": 83,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "10682401181"
    },
    {
      "job": 106655572741,
      "time": 97,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "NOTE",
      "artifact": "10681776380"
    },
    {
      "job": 106654809203,
      "time": 163,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "10682595546"
    },
    {
      "job": 106655572833,
      "time": 93,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "10682306271"
    },
    {
      "job": 106655572799,
      "time": 75,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "10681846327"
    },
    {
      "job": 106655572707,
      "time": 79,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "10682565831"
    },
    {
      "job": 106655572804,
      "time": 55,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "NOTE",
      "artifact": "10682675751"
    }
  ],
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.9.0",
      "role": "Depends"
    },
    {
      "package": "Biobase",
      "role": "Depends"
    },
    {
      "package": "fdrtool",
      "role": "Depends"
    },
    {
      "package": "MASS",
      "role": "Depends"
    },
    {
      "package": "survival",
      "role": "Depends"
    },
    {
      "package": "stats",
      "role": "Imports"
    }
  ],
  "_owner": "bioc",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 2
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.57.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.56.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "geneexpression",
    "genetics",
    "microarray"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "followers": 468,
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 577,
    "source": "https://www.bioconductor.org/packages/stats/bioc/HybridMTest"
  },
  "_mentions": 4,
  "_searchresults": 12,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/HybridMTest.html",
    "extra/manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "grenander.ebp",
    "hybrid.test",
    "row.kgrp.shapiro",
    "row.kruskal.wallis",
    "row.oneway.anova",
    "row.pearson",
    "row.slr.shapiro",
    "row.spearman"
  ],
  "_datasets": [
    {
      "name": "correlation.data",
      "title": "Sample ExpressionSet object of correlation.data",
      "object": "correlation.data",
      "file": "correlation.data.rda",
      "class": [
        "ExpressionSet"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "GroupComp.data",
      "title": "Sample ExpressionSet of GroupComp.data",
      "object": "GroupComp.data",
      "file": "GroupComp.data.rda",
      "class": [
        "ExpressionSet"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    }
  ],
  "_help": [
    {
      "page": "HybridMTest-package",
      "title": "A powerful tool in gene expression hypothesis testing.",
      "topics": [
        "HybridMTest-package"
      ]
    },
    {
      "page": "correlation.data",
      "title": "Sample ExpressionSet object of correlation.data",
      "topics": [
        "correlation.data"
      ]
    },
    {
      "page": "grenander.ebp",
      "title": "Grenander EBP.",
      "topics": [
        "grenander.ebp"
      ]
    },
    {
      "page": "GroupComp.data",
      "title": "Sample ExpressionSet of GroupComp.data",
      "topics": [
        "GroupComp.data"
      ]
    },
    {
      "page": "hybrid.test",
      "title": "Hybrid Multiple Testing of Gene Expression Data",
      "topics": [
        "hybrid.test"
      ]
    },
    {
      "page": "row.kgrp.shapiro",
      "title": "Shapiro Wilk test of normality.",
      "topics": [
        "row.kgrp.shapiro"
      ]
    },
    {
      "page": "row.kruskal.wallis",
      "title": "Apply the Kruskal-Wallis test many times",
      "topics": [
        "row.kruskal.wallis"
      ]
    },
    {
      "page": "row.oneway.anova",
      "title": "Perform one-way ANOVA for many variables.",
      "topics": [
        "row.oneway.anova"
      ]
    },
    {
      "page": "row.pearson",
      "title": "Compute the Pearson correlation of a variable x with many variables in a matrix Y",
      "topics": [
        "row.pearson"
      ]
    },
    {
      "page": "row.slr.shapiro",
      "title": "Test normality of residuals for many variables.",
      "topics": [
        "row.slr.shapiro"
      ]
    },
    {
      "page": "row.spearman",
      "title": "Compute Spearmans rank-based correlation of many variables with a variable x",
      "topics": [
        "row.spearman"
      ]
    }
  ],
  "_rundeps": [
    "Biobase",
    "BiocGenerics",
    "fdrtool",
    "generics",
    "lattice",
    "MASS",
    "Matrix",
    "survival"
  ],
  "_vignettes": [
    {
      "source": "HybridMTest.Rnw",
      "filename": "HybridMTest.pdf",
      "title": "Hybrid Multiple Testing",
      "engine": "utils::Sweave",
      "headings": [
        "Introduction",
        "Data Requirements",
        "Microarray Data Analysis",
        "Reference"
      ],
      "created": "2013-11-01 20:24:14",
      "modified": "2013-11-01 20:24:14",
      "commits": 1
    }
  ],
  "_score": 3.982271233039569,
  "_indexed": true,
  "_nocasepkg": "hybridmtest",
  "_universes": [
    "bioc"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.57.0",
      "date": "2026-09-22T07:35:01.000Z",
      "distro": "resolute",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/891bad71d01a1bcbb3f61758502c95bce478d7f8f751531cb72c3ada6cecbafd",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "1.57.0",
      "date": "2026-09-22T07:34:15.000Z",
      "distro": "resolute",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/ae5ee74e4e2a905074c87763d42b7d0767a2272202e9de28f560f265b884f022",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.57.0",
      "date": "2026-09-22T07:32:34.000Z",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/a2b2908d19629ceea5f9c11ae2123561784c00b58a0633617821e12b84e3bbea",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "1.57.0",
      "date": "2026-09-22T07:32:51.000Z",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/8fed0be67f4b7208681917b205ccbd50bda5454d7e13a7a8f49a7851a473868f",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.57.0",
      "date": "2026-09-22T07:33:02.000Z",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/c9f8e8cf7438632ff201b842fb648cc7bc66d229ee6d73efb021b7a2390a8d79",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.57.0",
      "date": "2026-09-22T07:32:12.000Z",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/67c1779f6b0a974969a9771eee362c2e48871b4248e13ce94d46173e22920c7e",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.57.0",
      "date": "2026-09-22T07:32:18.000Z",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/03dbae52c1531f2e15a31fc2111049f5009c05d556c5977f761806031a5e1674",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "1.57.0",
      "date": "2026-09-22T07:32:04.000Z",
      "commit": "412c9ecc7599e6f04b4938b0aca3cd5461f09336",
      "fileid": "https://r2.ropensci.org/b51973446e1602edeeb84ec73eb37ebb1e98b52b8cceabd1c2dac744d5a16c78",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc/actions/runs/35699754284"
    }
  ]
}