{
  "_id": "6ab7a9b499f7aa8c6aa33853",
  "Type": "Package",
  "Package": "HicAggR",
  "Title": "Set of 3D genomic interaction analysis tools",
  "Version": "1.9.0",
  "Authors@R": "c(\nperson(\"Robel\", \"Tesfaye\", email = \"rob.tesf@gmail.com\",\nrole = c(\"aut\",\"ctb\"), comment = c(ORCID=\"0000-0003-2358-219X\")),\nperson(\"David\", \"Depierre\", email = \"dav.depierre@gmail.com\",\nrole = \"aut\"),\nperson(\"Naomi\", \"Schickele\", email = \"naomi.schickele@univ-tlse3.fr\",\nrole = \"ctb\"),\nperson(\"Nicolas\", \"Chanard\", email = \"nico.chanard@gmail.com\",\nrole = \"aut\"),\nperson(\"Refka\", \"Askri\", email = \"refka.askri@univ-tlse3.fr\",\nrole = \"ctb\"),\nperson(\"Stéphane\", \"Schaak\", email = \"stephane.schaak@inserm.fr\",\nrole = c(\"aut\",\"ctb\")),\nperson(\"Pascal\", \"Martin\", email = \"pascal.martin@inra.fr\",\nrole = \"ctb\"),\nperson(\"Olivier\", \"Cuvier\", email = \"olivier.cuvier@univ-tlse3.fr\",\nrole = c(\"cre\",\"ctb\"), comment = c(ORCID=\"0000-0003-0644-2734\"))\n)",
  "Description": "This package provides a set of functions useful in the\nanalysis of 3D genomic interactions. It includes the import of\nstandard HiC data formats into R and HiC normalisation\nprocedures. The main objective of this package is to improve\nthe visualization and quantification of the analysis of HiC\ncontacts through aggregation. The package allows to import 1D\ngenomics data, such as peaks from ATACSeq, ChIPSeq, to create\npotential couples between features of interest under\nuser-defined parameters such as distance between pairs of\nfeatures of interest. It allows then the extraction of contact\nvalues from the HiC data for these couples and to perform\nAggregated Peak Analysis (APA) for visualization, but also to\ncompare normalized contact values between conditions. Overall\nthe package allows to integrate 1D genomics data with 3D\ngenomics data, providing an easy access to HiC contact values.",
  "biocViews": "Software, HiC, DataImport, DataRepresentation,\nNormalization, Visualization, DNA3DStructure, ATACSeq, ChIPSeq,\nDNaseSeq, RNASeq",
  "License": "MIT + file LICENSE",
  "URL": "https://bioconductor.org/packages/HicAggR,\nhttps://cuvierlab.github.io/HicAggR/,\nhttps://github.com/CuvierLab/HicAggR",
  "BugReports": "https://github.com/CuvierLab/HicAggR/issues",
  "VignetteBuilder": "knitr",
  "Encoding": "UTF-8",
  "LazyData": "false",
  "RoxygenNote": "7.3.2",
  "Config/testthat/edition": "3",
  "Roxygen": "list(markdown = TRUE)",
  "Config/pak/sysreqs": "make libbz2-dev libicu-dev liblzma-dev libxml2-dev\nlibssl-dev xz-utils zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 13:03:09 UTC",
  "RemoteUrl": "https://github.com/bioc/HicAggR",
  "RemoteRef": "HEAD",
  "RemoteSha": "4fcc34f03ac7182b2a2a2a3aa1f49978bbbfe4d0",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-09-26 11:04:17 UTC",
    "User": "root"
  },
  "Author": "Robel Tesfaye [aut, ctb] (ORCID:\n<https://orcid.org/0000-0003-2358-219X>),\nDavid Depierre [aut],\nNaomi Schickele [ctb],\nNicolas Chanard [aut],\nRefka Askri [ctb],\nStéphane Schaak [aut, ctb],\nPascal Martin [ctb],\nOlivier Cuvier [cre, ctb] (ORCID:\n<https://orcid.org/0000-0003-0644-2734>)",
  "Maintainer": "Olivier Cuvier <olivier.cuvier@univ-tlse3.fr>",
  "_user": "bioc",
  "_type": "src",
  "_file": "HicAggR_1.9.0.tar.gz",
  "_fileid": "https://r2.ropensci.org/40da2c9853a9036f73dea4be45dfb77889f96eec1171d49ec1a929e681a3a7d6",
  "_filesize": 2475479,
  "_sha256": "40da2c9853a9036f73dea4be45dfb77889f96eec1171d49ec1a929e681a3a7d6",
  "_expires": "2027-01-04T11:17:05.000Z",
  "_created": "2026-09-26T11:04:17.000Z",
  "_published": "2026-09-26T11:17:07.878Z",
  "_bioccheck": {
    "error": 0,
    "warning": 0,
    "note": 8
  },
  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/36237317711",
  "_status": "failure",
  "_upstream": "https://github.com/bioc/HicAggR",
  "_commit": {
    "id": "4fcc34f03ac7182b2a2a2a3aa1f49978bbbfe4d0",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
    "time": 1777381389
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  "_maintainer": {
    "name": "Olivier Cuvier",
    "email": "olivier.cuvier@univ-tlse3.fr",
    "login": "ocuvier",
    "description": "",
    "uuid": 165379677,
    "orcid": "0000-0003-0644-2734"
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      "package": "InteractionSet",
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  "_updates": [
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    "hic",
    "dataimport",
    "datarepresentation",
    "normalization",
    "visualization",
    "dna3dstructure",
    "atacseq",
    "chipseq",
    "dnaseseq",
    "rnaseq"
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      "uuid": 96891661
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    "name": "Bioconductor",
    "followers": 468,
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 330,
    "source": "https://www.bioconductor.org/packages/stats/bioc/HicAggR"
  },
  "_devurl": "https://github.com/cuvierlab/hicaggr",
  "_pkgdown": "https://cuvierlab.github.io/HicAggR/",
  "_searchresults": 6,
  "_rbuild": "4.6.1",
  "_assets": [
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    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/HicAggR.html",
    "extra/manual.pdf",
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    "extra/NEWS.txt",
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    "extra/readme.md",
    "LICENSE"
  ],
  "_homeurl": "https://github.com/cuvierlab/hicaggr",
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "Aggregation",
    "BalanceHiC",
    "BinGRanges",
    "CompareToBackground",
    "CutHiC",
    "ExtractSubmatrix",
    "FilterInteractions",
    "GenomicSystem",
    "GetInfo",
    "GetQuantif",
    "ggAPA",
    "Hue",
    "ICEnorm",
    "ImportHiC",
    "ImportLoops",
    "IndexFeatures",
    "JoinHiC",
    "MergeGRanges",
    "OrientateMatrix",
    "OverExpectedHiC",
    "PlotAPA",
    "plotMultiAPA",
    "PrepareMtxList",
    "preparePlotgardener",
    "QtlThreshold",
    "SearchPairs",
    "SeqEnds",
    "StrToGRanges",
    "SwitchMatrix",
    "VCnorm",
    "viridis",
    "YlGnBu",
    "YlOrRd"
  ],
  "_datasets": [
    {
      "name": "Beaf32_Peaks.gnr",
      "title": "D.melanogaster Beaf-32 ChIP-seq.",
      "object": "Beaf32_Peaks.gnr",
      "file": "Beaf32_Peaks.gnr.RData",
      "class": [
        "GRanges"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "HiC_Ctrl.cmx_lst",
      "title": "In situ Hi-C control.",
      "object": "HiC_Ctrl.cmx_lst",
      "file": "HiC_Ctrl.cmx_lst.RData",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "HiC_HS.cmx_lst",
      "title": "In situ Hi-C heat treated.",
      "object": "HiC_HS.cmx_lst",
      "file": "HiC_HS.cmx_lst.RData",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "TADs_Domains.gnr",
      "title": "D.melanogaster TADs.",
      "object": "TADs_Domains.gnr",
      "file": "TADs_Domains.gnr.RData",
      "class": [
        "GRanges"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "TSS_Peaks.gnr",
      "title": "D.melanogaster Transcription starting sites.",
      "object": "TSS_Peaks.gnr",
      "file": "TSS_Peaks.gnr.RData",
      "class": [
        "GRanges"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    }
  ],
  "_help": [
    {
      "page": "Aggregation",
      "title": "Aggregation of matrices list.",
      "topics": [
        "Aggregation"
      ]
    },
    {
      "page": "BalanceHiC",
      "title": "Compute HiC matrix-balancing.",
      "topics": [
        "BalanceHiC"
      ]
    },
    {
      "page": "Beaf32_Peaks.gnr",
      "title": "D.melanogaster Beaf-32 ChIP-seq.",
      "topics": [
        "Beaf32_Peaks.gnr"
      ]
    },
    {
      "page": "BinGRanges",
      "title": "Bin a GRanges.",
      "topics": [
        "BinGRanges"
      ]
    },
    {
      "page": "compareToBackground",
      "title": "CompareToBackground",
      "topics": [
        "CompareToBackground"
      ]
    },
    {
      "page": "CutHiC",
      "title": "Cut HiC map in chunks.",
      "topics": [
        "CutHiC"
      ]
    },
    {
      "page": "ExtractSubmatrix",
      "title": "Submatrix extraction.",
      "topics": [
        "ExtractSubmatrix"
      ]
    },
    {
      "page": "FilterInteractions",
      "title": "Submatrix or Interactions filtering.",
      "topics": [
        "FilterInteractions"
      ]
    },
    {
      "page": "GenomicSystem",
      "title": "Base pairs convertion.",
      "topics": [
        "GenomicSystem"
      ]
    },
    {
      "page": "GetInfo",
      "title": "get some basic information about your hic file",
      "topics": [
        "GetInfo"
      ]
    },
    {
      "page": "GetQuantif",
      "title": "Compute quantification on extracted submatrices.",
      "topics": [
        "GetQuantif"
      ]
    },
    {
      "page": "ggAPA",
      "title": "Aggregation plot",
      "topics": [
        "ggAPA"
      ]
    },
    {
      "page": "HiC_Ctrl.cmx_lst",
      "title": "In situ Hi-C control.",
      "topics": [
        "HiC_Ctrl.cmx_lst"
      ]
    },
    {
      "page": "HiC_HS.cmx_lst",
      "title": "In situ Hi-C heat treated.",
      "topics": [
        "HiC_HS.cmx_lst"
      ]
    },
    {
      "page": "Hue",
      "title": "Hue palette.",
      "topics": [
        "Hue"
      ]
    },
    {
      "page": "ICEnorm",
      "title": "Compute Iterative Correction.",
      "topics": [
        "ICEnorm"
      ]
    },
    {
      "page": "ImportHiC",
      "title": "Import Hic data",
      "topics": [
        "ImportHiC"
      ]
    },
    {
      "page": "IndexFeatures",
      "title": "Indexes GRanges on genome.",
      "topics": [
        "IndexFeatures"
      ]
    },
    {
      "page": "JoinHiC",
      "title": "Merge HiC chunk.",
      "topics": [
        "JoinHiC"
      ]
    },
    {
      "page": "MergeGRanges",
      "title": "Merge GRanges.",
      "topics": [
        "MergeGRanges"
      ]
    },
    {
      "page": "OrientateMatrix",
      "title": "Matrix orientation",
      "topics": [
        "OrientateMatrix"
      ]
    },
    {
      "page": "OverExpectedHiC",
      "title": "Genomic distance bias correction.",
      "topics": [
        "OverExpectedHiC"
      ]
    },
    {
      "page": "PlotAPA",
      "title": "Draw aggregation plot.",
      "topics": [
        "PlotAPA"
      ]
    },
    {
      "page": "plotMultiAPA",
      "title": "Draw aggregation plots for interactions with different distances.",
      "topics": [
        "plotMultiAPA"
      ]
    },
    {
      "page": "PrepareMtxList",
      "title": "Prepare matrices list for further analysis.",
      "topics": [
        "PrepareMtxList"
      ]
    },
    {
      "page": "preparePlotgardener",
      "title": "preparePlotgardener",
      "topics": [
        "preparePlotgardener"
      ]
    },
    {
      "page": "SearchPairs",
      "title": "Creates pairs from genomic index.",
      "topics": [
        "SearchPairs"
      ]
    },
    {
      "page": "SeqEnds",
      "title": "Get all sequences lengths.",
      "topics": [
        "SeqEnds"
      ]
    },
    {
      "page": "StrToGRanges",
      "title": "Convert String to GRanges.",
      "topics": [
        "StrToGRanges"
      ]
    },
    {
      "page": "SwitchMatrix",
      "title": "Change values of HiC map.",
      "topics": [
        "SwitchMatrix"
      ]
    },
    {
      "page": "TADs_Domains.gnr",
      "title": "D.melanogaster TADs.",
      "topics": [
        "TADs_Domains.gnr"
      ]
    },
    {
      "page": "TSS_Peaks.gnr",
      "title": "D.melanogaster Transcription starting sites.",
      "topics": [
        "TSS_Peaks.gnr"
      ]
    },
    {
      "page": "VCnorm",
      "title": "Compute Vanilla Count Correction.",
      "topics": [
        "VCnorm"
      ]
    },
    {
      "page": "viridis",
      "title": "viridis palette.",
      "topics": [
        "viridis"
      ]
    },
    {
      "page": "YlGnBu",
      "title": "YlGnBu palette.",
      "topics": [
        "YlGnBu"
      ]
    },
    {
      "page": "YlOrRd",
      "title": "YlOrRd palette.",
      "topics": [
        "YlOrRd"
      ]
    }
  ],
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  "_readme": "https://github.com/bioc/HicAggR/raw/HEAD/README.md",
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