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  "Title": "Conducting statistical inference on comparing the mutational\nexposures of mutational signatures by using hierarchical latent\nDirichlet allocation",
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  "Date": "2021-10-13",
  "Authors@R": "c(person(\"Zhi\", \"Yang\", email = \"zyang895@gmail.com\", \nrole = c(\"aut\", \"cre\")),\nperson(\"Yuichi\", \"Shiraishi\", email = \"friend1ws@gmail.com\",\nrole = \"ctb\"))",
  "Description": "A package built under the Bayesian framework of applying\nhierarchical latent Dirichlet allocation. It statistically\ntests whether the mutational exposures of mutational signatures\n(Shiraishi-model signatures) are different between two groups.\nThe package also provides inference and visualization.",
  "License": "GPL-3",
  "URL": "https://github.com/USCbiostats/HiLDA,\nhttps://doi.org/10.1101/577452",
  "BugReports": "https://github.com/USCbiostats/HiLDA/issues",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:50:34 UTC",
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    },
    {
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    },
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    {
      "page": "hildaBarplot",
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      "topics": [
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    },
    {
      "page": "hildaDiffPlot",
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      "topics": [
        "hildaDiffPlot"
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    },
    {
      "page": "hildaGlobalResult",
      "title": "Compute the Bayes factor",
      "topics": [
        "hildaGlobalResult"
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    {
      "page": "hildaLocalResult",
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      "topics": [
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    },
    {
      "page": "hildaPlotSignature",
      "title": "Plot mutation signatures from HiLDA output",
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    },
    {
      "page": "hildaReadMPFile",
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      "topics": [
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    {
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      "page": "pmPlotSignature",
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      "filename": "HiLDA.html",
      "title": "HiLDA: a package for testing the burdens of mutational signatures",
      "author": "Zhi Yang",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduction",
        "Paper",
        "Installing and loading the package",
        "Installation",
        "Bioconductor",
        "Just Another Gibbs Sampler (JAGS)",
        "Input data",
        "Mutation Position Format",
        "Workflow",
        "Get input data",
        "Run tests from HiLDA",
        "Perform the global test and the local test",
        "Get signatures from pmsignature",
        "Perform the global test and the local test with initial values",
        "Assess Convergence of MCMC chains",
        "Visualize the mutation signatures from pmsignature",
        "Visualize the mutation signatures from HiLDA",
        "Output the posterior distribution of the mean difference in exposures"
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      "created": "2019-06-22 06:52:24",
      "modified": "2019-06-22 06:52:24",
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