{
  "_id": "6a1ae9f61d7bb097a09f2dba",
  "Package": "HiCBricks",
  "Title": "Framework for Storing and Accessing Hi-C Data Through HDF Files",
  "Version": "1.31.0",
  "Description": "HiCBricks is a library designed for handling large\nhigh-resolution Hi-C datasets. Over the years, the Hi-C field\nhas experienced a rapid increase in the size and complexity of\ndatasets. HiCBricks is meant to overcome the challenges related\nto the analysis of such large datasets within the R\nenvironment. HiCBricks offers user-friendly and efficient\nsolutions for handling large high-resolution Hi-C datasets. The\npackage provides an R/Bioconductor framework with the bricks to\nbuild more complex data analysis pipelines and algorithms.\nHiCBricks already incorporates example algorithms for calling\ndomain boundaries and functions for high quality data\nvisualization.",
  "Date": "2025-07-22",
  "Type": "Package",
  "Author": "Koustav Pal [aut, cre], Carmen Livi [ctb], Ilario Tagliaferri\n[ctb]",
  "Maintainer": "Koustav Pal <koustav.pal@ifom.eu>",
  "License": "MIT + file LICENSE",
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  "biocViews": "DataImport, Infrastructure, Software, Technology,\nSequencing, HiC",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:48:57 UTC",
  "RemoteUrl": "https://github.com/bioc/HiCBricks",
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    "Brick_call_compartments",
    "Brick_export_to_sparse",
    "Brick_fetch_range_index",
    "Brick_fetch_row_vector",
    "Brick_get_bintable",
    "Brick_get_chrominfo",
    "Brick_get_entire_matrix",
    "Brick_get_matrix",
    "Brick_get_matrix_mcols",
    "Brick_get_matrix_within_coords",
    "Brick_get_ranges",
    "Brick_get_values_by_distance",
    "Brick_get_vector_values",
    "Brick_list_matrices",
    "Brick_list_matrix_mcols",
    "Brick_list_mcool_normalisations",
    "Brick_list_mcool_resolutions",
    "Brick_list_rangekeys",
    "Brick_list_ranges_mcols",
    "Brick_load_cis_matrix_till_distance",
    "Brick_load_data_from_mcool",
    "Brick_load_data_from_sparse",
    "Brick_load_matrix",
    "Brick_local_score_differentiator",
    "Brick_make_ranges",
    "Brick_matrix_dimensions",
    "Brick_matrix_exists",
    "Brick_matrix_filename",
    "Brick_matrix_isdone",
    "Brick_matrix_issparse",
    "Brick_matrix_maxdist",
    "Brick_matrix_minmax",
    "Brick_mcool_normalisation_exists",
    "Brick_rangekey_exists",
    "Brick_return_region_position",
    "Brick_vizart_plot_heatmap",
    "BrickContainer_change_experiment_name",
    "BrickContainer_change_output_directory",
    "BrickContainer_get_path_to_file",
    "BrickContainer_list_chromosomes",
    "BrickContainer_list_experiment_name",
    "BrickContainer_list_files",
    "BrickContainer_list_output_directory",
    "BrickContainer_list_resolutions",
    "BrickContainer_unlink_resolution",
    "Create_many_Bricks",
    "Create_many_Bricks_from_mcool",
    "load_BrickContainer"
  ],
  "_help": [
    {
      "page": "Brick_add_ranges",
      "title": "Store a ranges object in the Brick store.",
      "topics": [
        "Brick_add_ranges"
      ]
    },
    {
      "page": "Brick_call_compartments",
      "title": "Identify compartments in the Hi-C data",
      "topics": [
        "Brick_call_compartments"
      ]
    },
    {
      "page": "Brick_export_to_sparse",
      "title": "Export an entire resolution from a given BrickContainer as a upper triangle sparse matrix",
      "topics": [
        "Brick_export_to_sparse"
      ]
    },
    {
      "page": "Brick_fetch_range_index",
      "title": "Returns the position of the supplied ranges in the binning table associated to the Hi-C experiment.",
      "topics": [
        "Brick_fetch_range_index"
      ]
    },
    {
      "page": "Brick_fetch_row_vector",
      "title": "Return row or col vectors.",
      "topics": [
        "Brick_fetch_row_vector"
      ]
    },
    {
      "page": "Brick_get_bintable",
      "title": "Returns the binning table associated to the Hi-C experiment.",
      "topics": [
        "Brick_get_bintable"
      ]
    },
    {
      "page": "Brick_get_chrominfo",
      "title": "Get the chrominfo for the Hi-C experiment.",
      "topics": [
        "Brick_get_chrominfo"
      ]
    },
    {
      "page": "Brick_get_entire_matrix",
      "title": "Return an entire matrix for provided chromosome pair for a resolution.",
      "topics": [
        "Brick_get_entire_matrix"
      ]
    },
    {
      "page": "Brick_get_matrix",
      "title": "Return a matrix subset.",
      "topics": [
        "Brick_get_matrix"
      ]
    },
    {
      "page": "Brick_get_matrix_mcols",
      "title": "Get the matrix metadata columns in the Brick store.",
      "topics": [
        "Brick_get_matrix_mcols"
      ]
    },
    {
      "page": "Brick_get_matrix_within_coords",
      "title": "Return a matrix subset between two regions.",
      "topics": [
        "Brick_get_matrix_within_coords"
      ]
    },
    {
      "page": "Brick_get_ranges",
      "title": "Fetch the ranges associated to a rangekey or chromosome.",
      "topics": [
        "Brick_get_ranges"
      ]
    },
    {
      "page": "Brick_get_values_by_distance",
      "title": "Return values separated by a certain distance.",
      "topics": [
        "Brick_get_values_by_distance"
      ]
    },
    {
      "page": "Brick_get_vector_values",
      "title": "Return a N dimensional vector selection.",
      "topics": [
        "Brick_get_vector_values"
      ]
    },
    {
      "page": "Brick_list_matrices",
      "title": "List the matrix pairs present in the Brick store.",
      "topics": [
        "Brick_list_matrices"
      ]
    },
    {
      "page": "Brick_list_matrix_mcols",
      "title": "List the matrix metadata columns in the Brick store.",
      "topics": [
        "Brick_list_matrix_mcols"
      ]
    },
    {
      "page": "Brick_list_mcool_normalisations",
      "title": "Get all available normalisations in an mcool file.",
      "topics": [
        "Brick_list_mcool_normalisations"
      ]
    },
    {
      "page": "Brick_list_mcool_resolutions",
      "title": "Get all available normalisations in an mcool file.",
      "topics": [
        "Brick_list_mcool_resolutions"
      ]
    },
    {
      "page": "Brick_list_rangekeys",
      "title": "List the ranges tables stored within the Brick.",
      "topics": [
        "Brick_list_rangekeys"
      ]
    },
    {
      "page": "Brick_list_ranges_mcols",
      "title": "Find out what metadata columns are associated to a ranges with a certain name",
      "topics": [
        "Brick_list_ranges_mcols"
      ]
    },
    {
      "page": "Brick_load_cis_matrix_till_distance",
      "title": "Load a NxN dimensional sub-distance _cis_ matrix into the Brick store.",
      "topics": [
        "Brick_load_cis_matrix_till_distance"
      ]
    },
    {
      "page": "Brick_load_data_from_mcool",
      "title": "Load a NxN dimensional matrix into the Brick store from an mcool file.",
      "topics": [
        "Brick_load_data_from_mcool"
      ]
    },
    {
      "page": "Brick_load_data_from_sparse",
      "title": "Identify compartments in the Hi-C data",
      "topics": [
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      ]
    },
    {
      "page": "Brick_load_matrix",
      "title": "Load a NxM dimensional matrix into the Brick store.",
      "topics": [
        "Brick_load_matrix"
      ]
    },
    {
      "page": "Brick_local_score_differentiator",
      "title": "Do TAD Calls with Local Score Differentiator on a Hi-C matrix",
      "topics": [
        "Brick_local_score_differentiator"
      ]
    },
    {
      "page": "Brick_make_ranges",
      "title": "Creates a ranges object from provided vectors.",
      "topics": [
        "Brick_make_ranges"
      ]
    },
    {
      "page": "Brick_matrix_dimensions",
      "title": "Return the dimensions of a matrix",
      "topics": [
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      ]
    },
    {
      "page": "Brick_matrix_exists",
      "title": "Check if a chromosome pair exists.",
      "topics": [
        "Brick_matrix_exists"
      ]
    },
    {
      "page": "Brick_matrix_filename",
      "title": "Return the filename of the loaded matrix",
      "topics": [
        "Brick_matrix_filename"
      ]
    },
    {
      "page": "Brick_matrix_isdone",
      "title": "Check if a matrix has been loaded for a chromosome pair.",
      "topics": [
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      ]
    },
    {
      "page": "Brick_matrix_issparse",
      "title": "Check if a matrix for a chromosome pair is sparse.",
      "topics": [
        "Brick_matrix_issparse"
      ]
    },
    {
      "page": "Brick_matrix_maxdist",
      "title": "Get the maximum loaded distance from the diagonal of any matrix.",
      "topics": [
        "Brick_matrix_maxdist"
      ]
    },
    {
      "page": "Brick_matrix_minmax",
      "title": "Return the value range of the matrix",
      "topics": [
        "Brick_matrix_minmax"
      ]
    },
    {
      "page": "Brick_mcool_normalisation_exists",
      "title": "Check if a normalisation exists in an mcool file.",
      "topics": [
        "Brick_mcool_normalisation_exists"
      ]
    },
    {
      "page": "Brick_rangekey_exists",
      "title": "Check to see if the Brick contains a ranges with a certain name.",
      "topics": [
        "Brick_rangekey_exists"
      ]
    },
    {
      "page": "Brick_return_region_position",
      "title": "Provides the overlapping position (within) from the bintable.",
      "topics": [
        "Brick_return_region_position"
      ]
    },
    {
      "page": "Brick_vizart_plot_heatmap",
      "title": "Create the entire HDF5 structure and load the bintable",
      "topics": [
        "Brick_vizart_plot_heatmap"
      ]
    },
    {
      "page": "BrickContainer_change_experiment_name",
      "title": "Change the location of HDF files in the BrickContainer object",
      "topics": [
        "BrickContainer_change_experiment_name"
      ]
    },
    {
      "page": "BrickContainer_change_output_directory",
      "title": "Change the location of HDF files in the BrickContainer object",
      "topics": [
        "BrickContainer_change_output_directory"
      ]
    },
    {
      "page": "BrickContainer_get_path_to_file",
      "title": "Get the path to HDF files present in the Brick container.",
      "topics": [
        "BrickContainer_get_path_to_file"
      ]
    },
    {
      "page": "BrickContainer_list_chromosomes",
      "title": "Return the descriptive name of the BrickContainer",
      "topics": [
        "BrickContainer_list_chromosomes"
      ]
    },
    {
      "page": "BrickContainer_list_experiment_name",
      "title": "Return the descriptive name of the BrickContainer",
      "topics": [
        "BrickContainer_list_experiment_name"
      ]
    },
    {
      "page": "BrickContainer_list_files",
      "title": "Get the list of HDF files present in the Brick container.",
      "topics": [
        "BrickContainer_list_files"
      ]
    },
    {
      "page": "BrickContainer_list_output_directory",
      "title": "Return the output directory of the BrickContainer",
      "topics": [
        "BrickContainer_list_output_directory"
      ]
    },
    {
      "page": "BrickContainer_list_resolutions",
      "title": "Return the descriptive name of the BrickContainer",
      "topics": [
        "BrickContainer_list_resolutions"
      ]
    },
    {
      "page": "BrickContainer_unlink_resolution",
      "title": "Remove links to all Hi-C matrices for a given resolution.",
      "topics": [
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    },
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      "page": "Create_many_Bricks",
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      "topics": [
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    },
    {
      "page": "Create_many_Bricks_from_mcool",
      "title": "Create the entire HDF5 structure and load the bintable from a mcool file",
      "topics": [
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    },
    {
      "page": "HiCBricks",
      "title": "A package for storing, accessing and plotting Hi-C data",
      "topics": [
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    {
      "page": "load_BrickContainer",
      "title": "Create a BrickContainer object from a JSON file",
      "topics": [
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