{
  "_id": "6a1acafd1d7bb097a09ddb2c",
  "Package": "HELP",
  "Version": "1.71.0",
  "Date": "2009-09-30",
  "Title": "Tools for HELP data analysis",
  "Author": "Reid F. Thompson <reid.thompson@gmail.com>, John M. Greally\n<john.greally@einstein.yu.edu>, with contributions from Mark\nReimers <mreimers@vcu.edu>",
  "Maintainer": "Reid F. Thompson <reid.thompson@gmail.com>",
  "Description": "The package contains a modular pipeline for analysis of\nHELP microarray data, and includes graphical and mathematical\ntools with more general applications.",
  "License": "GPL (>= 2)",
  "biocViews": "CpGIsland, DNAMethylation, Microarray, TwoChannel,\nDataImport, QualityControl, Preprocessing, Visualization",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:32:59 UTC",
  "RemoteUrl": "https://github.com/bioc/HELP",
  "RemoteRef": "HEAD",
  "RemoteSha": "74ec2b221c804df97a2d518c39ae4b281c9c3dca",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 08:00:14 UTC",
    "User": "root"
  },
  "MD5sum": "88f341d3673f47d911f4746ee7c1bfab",
  "_user": "bioc",
  "_type": "src",
  "_file": "HELP_1.71.0.tar.gz",
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  "_created": "2026-05-30T08:00:14.000Z",
  "_published": "2026-05-30T11:33:17.551Z",
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    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
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    "email": "reid.thompson@gmail.com",
    "login": "reidt03",
    "description": "",
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  "_usedby": 0,
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    "dataimport",
    "qualitycontrol",
    "preprocessing",
    "visualization"
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    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
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    "extra/citation.json",
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    "manual.pdf"
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  "_cranurl": false,
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    "calcPrototype",
    "calcTm",
    "combineData",
    "createWiggle",
    "exprs2",
    "exprs2<-",
    "fuzzyMatches",
    "getFeatures",
    "getSamples",
    "plotBins",
    "plotChip",
    "plotFeature",
    "plotPairs",
    "quantileNormalize",
    "readDesign",
    "readPairs",
    "readSampleKey"
  ],
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      "title": "Base-stacking thermodynamic parameters",
      "object": "base.stacking.thermodynamics",
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        "array"
      ],
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        "dS"
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      "table": true,
      "tojson": true
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      "page": "base.stacking.thermodynamics",
      "title": "Base-stacking thermodynamic parameters",
      "topics": [
        "base.stacking.thermodynamics"
      ]
    },
    {
      "page": "calcGC",
      "title": "Calculate GC percent",
      "topics": [
        "calcGC"
      ]
    },
    {
      "page": "calcGC-methods",
      "title": "Calculate GC percent (methods)",
      "topics": [
        "calcGC,character-method",
        "calcGC,ExpressionSet-method",
        "calcGC,missing-method",
        "calcGC,NULL-method",
        "calcGC-methods"
      ]
    },
    {
      "page": "calcPrototype",
      "title": "Calculate prototype",
      "topics": [
        "calcPrototype"
      ]
    },
    {
      "page": "calcPrototype-methods",
      "title": "Calculate prototype (methods)",
      "topics": [
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        "calcPrototype,matrix-method",
        "calcPrototype,missing-method",
        "calcPrototype,vector-method",
        "calcPrototype-methods"
      ]
    },
    {
      "page": "calcTm",
      "title": "Calculate Tm",
      "topics": [
        "calcTm"
      ]
    },
    {
      "page": "calcTm-methods",
      "title": "Calculate Tm (methods)",
      "topics": [
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        "calcTm,ExpressionSet-method",
        "calcTm,missing-method",
        "calcTm,NULL-method",
        "calcTm-methods"
      ]
    },
    {
      "page": "combineData",
      "title": "Combine data",
      "topics": [
        "combineData"
      ]
    },
    {
      "page": "combineData-methods",
      "title": "Combine data (methods)",
      "topics": [
        "combineData,ExpressionSet,missing,missing-method",
        "combineData,ExpressionSet,vector,missing-method",
        "combineData,matrix,vector,matrix-method",
        "combineData,matrix,vector,missing-method",
        "combineData,missing,missing,missing-method",
        "combineData,vector,missing,missing-method",
        "combineData,vector,missing,vector-method",
        "combineData,vector,vector,missing-method",
        "combineData,vector,vector,vector-method",
        "combineData-methods"
      ]
    },
    {
      "page": "createWiggle",
      "title": "Create wiggle track",
      "topics": [
        "createWiggle"
      ]
    },
    {
      "page": "createWiggle-methods",
      "title": "Create wiggle track (methods)",
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        "createWiggle,ExpressionSet,missing-method",
        "createWiggle,matrix,matrix-method",
        "createWiggle,missing,missing-method",
        "createWiggle,vector,matrix-method",
        "createWiggle-methods"
      ]
    },
    {
      "page": "exprs2",
      "title": "Retrieve microarray data (for signal channel 2) from ExpressionSets",
      "topics": [
        "exprs2",
        "exprs2<-"
      ]
    },
    {
      "page": "exprs2-methods",
      "title": "Retrieve microarray data (for signal channel 2) from ExpressionSets (methods)",
      "topics": [
        "exprs2,ExpressionSet-method",
        "exprs2,missing-method",
        "exprs2-methods",
        "exprs2<-,ExpressionSet,matrix-method",
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      ]
    },
    {
      "page": "fuzzyMatches",
      "title": "Fuzzy matching",
      "topics": [
        "fuzzyMatches"
      ]
    },
    {
      "page": "fuzzyMatches-methods",
      "title": "Fuzzy matching (methods)",
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        "fuzzyMatches,NULL,vector-method",
        "fuzzyMatches,vector,missing-method",
        "fuzzyMatches,vector,NULL-method",
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      ]
    },
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      "page": "getFeatures",
      "title": "Get features (methods)",
      "topics": [
        "getFeatures"
      ]
    },
    {
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      "title": "Get features (methods)",
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        "getFeatures,AnnotatedDataFrame,NULL-method",
        "getFeatures,AnnotatedDataFrame,vector-method",
        "getFeatures,ExpressionSet,missing-method",
        "getFeatures,ExpressionSet,NULL-method",
        "getFeatures,ExpressionSet,vector-method",
        "getFeatures,matrix,vector-method",
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        "getFeatures,vector,missing-method",
        "getFeatures,vector,NULL-method",
        "getFeatures,vector,vector-method",
        "getFeatures-methods"
      ]
    },
    {
      "page": "getSamples",
      "title": "Get samples",
      "topics": [
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      ]
    },
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      "title": "Get samples (methods)",
      "topics": [
        "getSamples,ExpressionSet,missing-method",
        "getSamples,ExpressionSet,NULL-method",
        "getSamples,ExpressionSet,vector-method",
        "getSamples,matrix,missing-method",
        "getSamples,matrix,NULL-method",
        "getSamples,matrix,vector-method",
        "getSamples,missing,missing-method",
        "getSamples,vector,missing-method",
        "getSamples,vector,NULL-method",
        "getSamples,vector,vector-method",
        "getSamples-methods"
      ]
    },
    {
      "page": "plotBins",
      "title": "Plot bins",
      "topics": [
        "plotBins"
      ]
    },
    {
      "page": "plotBins-methods",
      "title": "Plot bins (methods)",
      "topics": [
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        "plotBins,ExpressionSet,missing-method",
        "plotBins,ExpressionSet,vector-method",
        "plotBins,matrix,missing-method",
        "plotBins,missing,missing-method",
        "plotBins,vector,ExpressionSet-method",
        "plotBins,vector,missing-method",
        "plotBins,vector,vector-method",
        "plotBins-methods"
      ]
    },
    {
      "page": "plotChip",
      "title": "Plot chip image",
      "topics": [
        "plotChip"
      ]
    },
    {
      "page": "plotChip-methods",
      "title": "Plot chip image (methods)",
      "topics": [
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        "plotChip,ExpressionSet,missing,missing-method",
        "plotChip,ExpressionSet,vector,missing-method",
        "plotChip,matrix,missing,missing-method",
        "plotChip,missing,missing,missing-method",
        "plotChip,vector,vector,ExpressionSet-method",
        "plotChip,vector,vector,vector-method",
        "plotChip-methods"
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    },
    {
      "page": "plotFeature",
      "title": "Plot feature versus two-color intensity",
      "topics": [
        "plotFeature"
      ]
    },
    {
      "page": "plotFeature-methods",
      "title": "Plot feature versus two-color intensity (methods)",
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        "plotFeature,ExpressionSet,vector-method",
        "plotFeature,matrix,vector-method",
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