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  "Package": "HD2013SGI",
  "Type": "Package",
  "Title": "Mapping genetic interactions in human cancer cells with RNAi and\nmultiparametric phenotyping",
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  "Authors@R": "c(\nperson(given = \"Bernd\", family = \"Fischer\", role = \"aut\"),\nperson(given = \"Hugo\", family = \"Gruson\", email = \"hugo.gruson@embl.de\", role = \"cre\")\n)",
  "Description": "This package contains the experimental data and a complete\nexecutable transcript (vignette) of the analysis of the HCT116\ngenetic interaction matrix presented in the paper \"Mapping\ngenetic interactions in human cancer cells with RNAi and\nmultiparametric phenotyping\" by C. Laufer, B. Fischer, M.\nBillmann, W. Huber, M. Boutros; Nature Methods (2013)\n10:427-31. doi: 10.1038/nmeth.2436.",
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  "SystemRequirements": "GNU make",
  "biocViews": "ExperimentData, CancerData, ColonCancerData,\nMicrotitrePlateAssayData, CellCulture, Homo_sapiens_Data,\nHighThroughputImagingData",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-08-20 12:01:04 UTC",
  "RemoteUrl": "https://github.com/bioc/HD2013SGI",
  "RemoteRef": "HEAD",
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  "Packaged": {
    "Date": "2026-10-10 10:38:12 UTC",
    "User": "root"
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  "Author": "Bernd Fischer [aut],\nHugo Gruson [cre]",
  "Maintainer": "Hugo Gruson <hugo.gruson@embl.de>",
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  "_created": "2026-10-10T10:38:12.000Z",
  "_published": "2026-10-10T10:43:22.331Z",
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      "page": "HD2013SGI-package",
      "title": "Experimental Data and Analysis of the HCT116 Genetic Interaction Matrix",
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      "title": "Phenotypic data after quality control and feature selection",
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      "page": "datamatrixfull",
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      "title": "Download a dataset from the HD2013SGI package",
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      "title": "Plotting heatmaps of genetic interaction scores",
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      "title": "Estimation of main effects",
      "topics": [
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      "page": "HD2013SGIorderDim",
      "title": "hclust on one out of three dimensions of an interaction matrix",
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      "page": "Interactions",
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      "page": "mainEffects",
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      "page": "nrOfInteractionsPerTarget",
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