{
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  "Package": "GenomicPlot",
  "Type": "Package",
  "Title": "Plot profiles of next generation sequencing data in genomic\nfeatures",
  "Version": "1.11.0",
  "Authors@R": "person(\"Shuye\", \"Pu\", email = \"shuye2009@gmail.com\", role = c(\"aut\", \"cre\"), \ncomment = c(ORCID = \"0000-0002-6664-8438\"))",
  "Author": "Shuye Pu <shuye2009@gmail.com>",
  "Maintainer": "Shuye Pu <shuye2009@gmail.com>",
  "Description": "Visualization of next generation sequencing (NGS) data is\nessential for interpreting high-throughput genomics experiment\nresults. 'GenomicPlot' facilitates plotting of NGS data in\nvarious formats (bam, bed, wig and bigwig); both coverage and\nenrichment over input can be computed and displayed with\nrespect to genomic features (such as UTR, CDS, enhancer), and\nuser defined genomic loci or regions. Statistical tests on\nsignal intensity within user defined regions of interest can be\nperformed and represented as boxplots or bar graphs. Parallel\nprocessing is used to speed up computation on multicore\nplatforms. In addition to genomic plots which is suitable for\ndisplaying of coverage of genomic DNA (such as ChIPseq data),\nmetagenomic (without introns) plots can also be made for RNAseq\nor CLIPseq data as well.",
  "License": "GPL-2",
  "Encoding": "UTF-8",
  "LazyData": "FALSE",
  "Collate": "\"DrawingFunctions.R\" \"GenomicPlot.R\" \"HandleDataMatrix.R\"\n\"HandleFeatures.R\" \"Parallel.R\" \"ReadData.R\" \"Setup.R\"\n\"Plot_5parts_metagene.R\" \"Plot_start_end.R\"\n\"Plot_start_end_with_random.R\" \"Plot_region.R\" \"Plot_locus.R\"\n\"data.R\" \"Plot_locus_with_random.R\" \"Plot_peak_annotation.R\"\n\"Plot_bam_correlation.R\"",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 13:01:23 UTC",
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    "check_constraints",
    "custom_TxDb_from_GTF",
    "draw_boxplot_by_factor",
    "draw_boxplot_wo_outlier",
    "draw_combo_plot",
    "draw_locus_profile",
    "draw_matrix_heatmap",
    "draw_mean_se_barplot",
    "draw_quantile_plot",
    "draw_rank_plot",
    "draw_region_landmark",
    "draw_region_name",
    "draw_region_profile",
    "draw_stacked_plot",
    "draw_stacked_profile",
    "effective_size",
    "extract_longest_tx",
    "filter_by_nonoverlaps_stranded",
    "filter_by_overlaps_nonstranded",
    "filter_by_overlaps_stranded",
    "gene2tx",
    "get_genomic_feature_coordinates",
    "get_targeted_genes",
    "get_txdb_features",
    "gr2df",
    "handle_bam",
    "handle_bed",
    "handle_bedGraph",
    "handle_bw",
    "handle_input",
    "handle_wig",
    "make_subTxDb_from_GTF",
    "overlap_pair",
    "overlap_quad",
    "overlap_triple",
    "parallel_countOverlaps",
    "parallel_scoreMatrixBin",
    "plot_5parts_metagene",
    "plot_bam_correlation",
    "plot_locus",
    "plot_locus_with_random",
    "plot_overlap_bed",
    "plot_overlap_genes",
    "plot_peak_annotation",
    "plot_region",
    "plot_start_end",
    "plot_start_end_with_random",
    "prepare_3parts_genomic_features",
    "prepare_5parts_genomic_features",
    "process_scoreMatrix",
    "rank_rows",
    "rm_outlier",
    "set_seqinfo",
    "setImportParams",
    "start_parallel",
    "stop_parallel"
  ],
  "_datasets": [
    {
      "name": "gf5_genomic",
      "title": "Toy data for examples and testing of the 'GenomicPlot' package",
      "object": "gf5_genomic",
      "file": "gf5_genomic.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "gf5_meta",
      "title": "Toy data for examples and testing of the 'GenomicPlot' package",
      "object": "gf5_meta",
      "file": "gf5_meta.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    }
  ],
  "_help": [
    {
      "page": "aov_TukeyHSD",
      "title": "Perform one-way ANOVA and post hoc TukeyHSD tests",
      "topics": [
        "aov_TukeyHSD"
      ]
    },
    {
      "page": "check_constraints",
      "title": "Check constraints of genomic ranges",
      "topics": [
        "check_constraints"
      ]
    },
    {
      "page": "custom_TxDb_from_GTF",
      "title": "Make custom TxDb object from a GTF/GFF file",
      "topics": [
        "custom_TxDb_from_GTF"
      ]
    },
    {
      "page": "draw_boxplot_by_factor",
      "title": "Plot boxplot with two factors",
      "topics": [
        "draw_boxplot_by_factor"
      ]
    },
    {
      "page": "draw_boxplot_wo_outlier",
      "title": "Plot boxplot without outliers",
      "topics": [
        "draw_boxplot_wo_outlier"
      ]
    },
    {
      "page": "draw_combo_plot",
      "title": "Make combo plot for statistics plots",
      "topics": [
        "draw_combo_plot"
      ]
    },
    {
      "page": "draw_locus_profile",
      "title": "Plot signal profile around genomic loci",
      "topics": [
        "draw_locus_profile"
      ]
    },
    {
      "page": "draw_matrix_heatmap",
      "title": "Display matrix as a heatmap",
      "topics": [
        "draw_matrix_heatmap"
      ]
    },
    {
      "page": "draw_mean_se_barplot",
      "title": "Plot barplot for mean with standard error bars",
      "topics": [
        "draw_mean_se_barplot"
      ]
    },
    {
      "page": "draw_quantile_plot",
      "title": "Plot quantile over value",
      "topics": [
        "draw_quantile_plot"
      ]
    },
    {
      "page": "draw_rank_plot",
      "title": "Plot fraction of cumulative sum over rank",
      "topics": [
        "draw_rank_plot"
      ]
    },
    {
      "page": "draw_region_landmark",
      "title": "Plot genomic region landmark indicator",
      "topics": [
        "draw_region_landmark"
      ]
    },
    {
      "page": "draw_region_name",
      "title": "Plot genomic region names",
      "topics": [
        "draw_region_name"
      ]
    },
    {
      "page": "draw_region_profile",
      "title": "Plot signal profile in genomic regions",
      "topics": [
        "draw_region_profile"
      ]
    },
    {
      "page": "draw_stacked_plot",
      "title": "draw stacked plot",
      "topics": [
        "draw_stacked_plot"
      ]
    },
    {
      "page": "draw_stacked_profile",
      "title": "Plot signal profile around start, center, and end of genomic regions",
      "topics": [
        "draw_stacked_profile"
      ]
    },
    {
      "page": "effective_size",
      "title": "Normalize sample library size to effective size",
      "topics": [
        "effective_size"
      ]
    },
    {
      "page": "extdata",
      "title": "Toy data for examples and testing of the `GenomicPlot` package",
      "topics": [
        "chip_input_chr19.bam",
        "chip_treat_chr19.bam",
        "extdata",
        "gencode.v19.annotation_chr19.gtf",
        "input_chr19.bam",
        "test_chip_peak_chr19.bed",
        "test_chip_peak_chr19.narrowPeak",
        "test_chr19.bedGraph",
        "test_clip_peak_chr19.bed",
        "test_file1.txt",
        "test_file2.txt",
        "test_file3.txt",
        "test_file4.txt",
        "test_wig_chr19_+.bw",
        "test_wig_chr19_+.wig",
        "treat_chr19.bam"
      ]
    },
    {
      "page": "extract_longest_tx",
      "title": "Extract the longest transcript for each protein-coding genes",
      "topics": [
        "extract_longest_tx"
      ]
    },
    {
      "page": "filter_by_nonoverlaps_stranded",
      "title": "Filter GRanges by nonoverlaps in a stranded way",
      "topics": [
        "filter_by_nonoverlaps_stranded"
      ]
    },
    {
      "page": "filter_by_overlaps_nonstranded",
      "title": "Filter GRanges by overlaps in a nonstranded way",
      "topics": [
        "filter_by_overlaps_nonstranded"
      ]
    },
    {
      "page": "filter_by_overlaps_stranded",
      "title": "Filter GRanges by overlaps in a stranded way",
      "topics": [
        "filter_by_overlaps_stranded"
      ]
    },
    {
      "page": "gene2tx",
      "title": "Translate gene names to transcript ids using a GTF file for a subset of genes",
      "topics": [
        "gene2tx"
      ]
    },
    {
      "page": "GenomicPlot",
      "title": "GenomicPlot-package",
      "topics": [
        "GenomicPlot"
      ]
    },
    {
      "page": "get_genomic_feature_coordinates",
      "title": "Extract genomic features from TxDb object",
      "topics": [
        "get_genomic_feature_coordinates"
      ]
    },
    {
      "page": "get_targeted_genes",
      "title": "Get the number of peaks overlapping each feature of all protein-coding genes",
      "topics": [
        "get_targeted_genes"
      ]
    },
    {
      "page": "get_txdb_features",
      "title": "Get genomic coordinates of features of protein-coding genes",
      "topics": [
        "get_txdb_features"
      ]
    },
    {
      "page": "gf5_genomic",
      "title": "Toy data for examples and testing of the `GenomicPlot` package",
      "topics": [
        "gf5_genomic"
      ]
    },
    {
      "page": "gf5_meta",
      "title": "Toy data for examples and testing of the `GenomicPlot` package",
      "topics": [
        "gf5_meta"
      ]
    },
    {
      "page": "gr2df",
      "title": "Convert GRanges to dataframe",
      "topics": [
        "gr2df"
      ]
    },
    {
      "page": "handle_bam",
      "title": "Handle files in bam format",
      "topics": [
        "handle_bam"
      ]
    },
    {
      "page": "handle_bed",
      "title": "Handle files in bed|narrowPeak|broadPeak format",
      "topics": [
        "handle_bed"
      ]
    },
    {
      "page": "handle_bedGraph",
      "title": "Handle files in bedGraph format",
      "topics": [
        "handle_bedGraph"
      ]
    },
    {
      "page": "handle_bw",
      "title": "Handle files in bw|bigwig|bigWig|BigWig|BW|BIGWIG format",
      "topics": [
        "handle_bw"
      ]
    },
    {
      "page": "handle_input",
      "title": "Handle import of NGS data with various formats",
      "topics": [
        "handle_input"
      ]
    },
    {
      "page": "handle_wig",
      "title": "Handle files in wig format",
      "topics": [
        "handle_wig"
      ]
    },
    {
      "page": "make_subTxDb_from_GTF",
      "title": "Make TxDb object from a GTF file for a subset of genes",
      "topics": [
        "make_subTxDb_from_GTF"
      ]
    },
    {
      "page": "overlap_pair",
      "title": "Plot two-sets Venn diagram",
      "topics": [
        "overlap_pair"
      ]
    },
    {
      "page": "overlap_quad",
      "title": "Plot four-sets Venn diagram",
      "topics": [
        "overlap_quad"
      ]
    },
    {
      "page": "overlap_triple",
      "title": "Plot three-sets Venn diagram",
      "topics": [
        "overlap_triple"
      ]
    },
    {
      "page": "parallel_countOverlaps",
      "title": "Parallel execution of countOverlaps",
      "topics": [
        "parallel_countOverlaps"
      ]
    },
    {
      "page": "parallel_scoreMatrixBin",
      "title": "Parallel execution of scoreMatrixBin on a huge target windows object split into chunks",
      "topics": [
        "parallel_scoreMatrixBin"
      ]
    },
    {
      "page": "plot_5parts_metagene",
      "title": "Plot promoter, 5'UTR, CDS, 3'UTR and TTS",
      "topics": [
        "plot_5parts_metagene"
      ]
    },
    {
      "page": "plot_bam_correlation",
      "title": "Plot correlation of bam files",
      "topics": [
        "plot_bam_correlation"
      ]
    },
    {
      "page": "plot_locus",
      "title": "Plot signal around custom genomic loci",
      "topics": [
        "plot_locus"
      ]
    },
    {
      "page": "plot_locus_with_random",
      "title": "Plot signal around custom genomic loci and random loci for comparison",
      "topics": [
        "plot_locus_with_random"
      ]
    },
    {
      "page": "plot_overlap_bed",
      "title": "Plot Venn diagrams depicting overlap of genomic regions",
      "topics": [
        "plot_overlap_bed"
      ]
    },
    {
      "page": "plot_overlap_genes",
      "title": "Plot Venn diagrams depicting overlap of gene lists",
      "topics": [
        "plot_overlap_genes"
      ]
    },
    {
      "page": "plot_peak_annotation",
      "title": "Annotate peaks with genomic features and genes",
      "topics": [
        "plot_peak_annotation"
      ]
    },
    {
      "page": "plot_region",
      "title": "Plot signal inside as well as around custom genomic regions",
      "topics": [
        "plot_region"
      ]
    },
    {
      "page": "plot_start_end",
      "title": "Plot signals around the start and the end of genomic features",
      "topics": [
        "plot_start_end"
      ]
    },
    {
      "page": "plot_start_end_with_random",
      "title": "Plot signals around the start and the end of genomic features and random regions",
      "topics": [
        "plot_start_end_with_random"
      ]
    },
    {
      "page": "prepare_3parts_genomic_features",
      "title": "Demarcate genes into promoter, gene body and TTS features",
      "topics": [
        "prepare_3parts_genomic_features"
      ]
    },
    {
      "page": "prepare_5parts_genomic_features",
      "title": "Demarcate genes into promoter, 5'UTR, CDS, 3'UTR and TTS features",
      "topics": [
        "prepare_5parts_genomic_features"
      ]
    },
    {
      "page": "process_scoreMatrix",
      "title": "Preprocess scoreMatrix before plotting",
      "topics": [
        "process_scoreMatrix"
      ]
    },
    {
      "page": "rank_rows",
      "title": "Rank rows of a matrix based on user input",
      "topics": [
        "rank_rows"
      ]
    },
    {
      "page": "rm_outlier",
      "title": "Remove outliers from scoreMatrix",
      "topics": [
        "rm_outlier"
      ]
    },
    {
      "page": "set_seqinfo",
      "title": "Set standard chromosome size of model organisms",
      "topics": [
        "set_seqinfo"
      ]
    },
    {
      "page": "setImportParams",
      "title": "set parameters for 'handle_input' function",
      "topics": [
        "setImportParams"
      ]
    },
    {
      "page": "start_parallel",
      "title": "Prepare for parallel processing",
      "topics": [
        "start_parallel"
      ]
    },
    {
      "page": "stop_parallel",
      "title": "Stop parallel processing",
      "topics": [
        "stop_parallel"
      ]
    },
    {
      "page": "txdb.sql",
      "title": "Toy data for examples and testing of the `GenomicPlot` package",
      "topics": [
        "txdb.sql"
      ]
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      "source": "GenomicPlot_vignettes.rmd",
      "filename": "GenomicPlot_vignettes.html",
      "title": "GenomicPlot: an R package for efficient and flexible visualization of genome-wide NGS coverage profiles",
      "author": "Shuye Pu",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduction",
        "Installation",
        "Core functions",
        "Plot gene/metagene with 5'UTR, CDS and 3'UTR",
        "Plot along the ranges of genomic features",
        "Plot genomic loci (start, end or center of a feature)",
        "Plot peak annotation statistics",
        "Auxillary functions",
        "Plot bam correlations",
        "Plot bed overlaps",
        "Appendix",
        "Session info"
      ],
      "created": "2023-02-07 16:35:41",
      "modified": "2025-12-08 21:12:45",
      "commits": 23
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