{
  "_id": "6a1acf0f1d7bb097a09e0446",
  "Package": "GenomAutomorphism",
  "Title": "Compute the automorphisms between DNA's Abelian group\nrepresentations",
  "Version": "1.15.0",
  "Authors@R": "person( given = \"Robersy\",\nfamily = \"Sanchez\",\nrole = c(\"aut\", \"cre\"),\nemail = \"genomicmath@gmail.com\",\ncomment = c(ORCID = \"0000-0002-5246-1453\"))",
  "URL": "https://github.com/genomaths/GenomAutomorphism",
  "BugReports": "https://github.com/genomaths/GenomAutomorphism/issues",
  "Description": "This is a R package to compute the automorphisms between\npairwise aligned DNA sequences represented as elements from a\nGenomic Abelian group. In a general scenario, from genomic\nregions till the whole genomes from a given population (from\nany species or close related species) can be algebraically\nrepresented as a direct sum of cyclic groups or more\nspecifically Abelian p-groups. Basically, we propose the\nrepresentation of multiple sequence alignments of length N bp\nas element of a finite Abelian group created by the direct sum\nof homocyclic Abelian group of prime-power order.",
  "License": "Artistic-2.0",
  "Encoding": "UTF-8",
  "biocViews": "MathematicalBiology, ComparativeGenomics,\nFunctionalGenomics, MultipleSequenceAlignment, WholeGenome",
  "RoxygenNote": "7.3.2",
  "Roxygen": "list(markdown = TRUE)",
  "Language": "en-US",
  "LazyData": "false",
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  "VignetteBuilder": "knitr",
  "Config/pak/sysreqs": "zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:58:46 UTC",
  "RemoteUrl": "https://github.com/bioc/GenomAutomorphism",
  "RemoteRef": "HEAD",
  "RemoteSha": "34d8013455723cf11bc1b6c548fefc8e46ee9b8d",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-30 08:14:35 UTC",
    "User": "root"
  },
  "Author": "Robersy Sanchez [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-5246-1453>)",
  "Maintainer": "Robersy Sanchez <genomicmath@gmail.com>",
  "MD5sum": "6dba453981c43b560ca77e48f32b08a9",
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  "_type": "src",
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  "_created": "2026-05-30T08:14:35.000Z",
  "_published": "2026-05-30T11:50:39.105Z",
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    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to odd y following creation of RELEASE_3_23 branch\n",
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    "comparativegenomics",
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  "_homeurl": "https://github.com/genomaths/genomautomorphism",
  "_realowner": "bioc",
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  "_exports": [
    "aa_index",
    "aa_mutmat",
    "aa_phychem_index",
    "AAMultipleAlignment",
    "AAStringSet",
    "aminoacid_dist",
    "as.AutomorphismList",
    "as.list",
    "aut3D",
    "automorphism_bycoef",
    "automorphism_prob",
    "automorphismByRanges",
    "automorphisms",
    "autZ125",
    "autZ5",
    "autZ64",
    "base_coord",
    "base_matrix",
    "base_seq2string_set",
    "base2codon",
    "base2int",
    "codon_coord",
    "codon_dist",
    "codon_dist_matrix",
    "codon_matrix",
    "CodonMatrix",
    "colMeans2",
    "colSds",
    "colSums2",
    "colVars",
    "conserved_regions",
    "coordList",
    "dna_phychem",
    "DNAMultipleAlignment",
    "DNAStringSet",
    "end",
    "end<-",
    "GENETIC_CODE_TABLE",
    "get_coord",
    "get_mutscore",
    "getAutomorphisms",
    "getGeneticCode",
    "GRangesList",
    "GRangesMatrixSeq",
    "ListCodonMatrix",
    "makeGRangesFromDataFrame",
    "matrices",
    "MatrixSeq",
    "mcols",
    "mcols<-",
    "mod",
    "modeq",
    "modlin",
    "modlineq",
    "modq",
    "mut_type",
    "peptide_phychem_index",
    "readDNAMultipleAlignment",
    "rowMeans2",
    "rowSds",
    "rowSums2",
    "rowVars",
    "seq2granges",
    "seqranges",
    "seqRanges",
    "setValidity2",
    "show",
    "slapply",
    "sortByChromAndEnd",
    "sortByChromAndStart",
    "start",
    "start<-",
    "str2chr",
    "str2dig",
    "strand",
    "strand<-",
    "subseq",
    "translate",
    "translation",
    "unmasked",
    "width"
  ],
  "_datasets": [
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      "name": "aaindex1",
      "title": "List of 571 Amino Acid Physicochemical Indexes from AAindex Database",
      "object": "aaindex1",
      "file": "aaindex1.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "aaindex2",
      "title": "List of 94 Amino Acid Matrices from AAindex",
      "object": "aaindex2",
      "file": "aaindex2.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "aaindex3",
      "title": "Statistical protein contact potentials matrices from AAindex ver.9.2",
      "object": "aaindex3",
      "file": "aaindex3.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "aln",
      "title": "Simulated 'DNAStringSet' class object",
      "object": "aln",
      "file": "aln.rda",
      "class": [
        "DNAStringSet"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "autby_coef",
      "title": "Automorphisms between DNA Primate BRCA1 Genes Grouped by Coefficients",
      "object": "autby_coef",
      "file": "autby_coef.rda",
      "class": [
        "AutomorphismByCoefList"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "autm",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "object": "autm",
      "file": "autm.rda",
      "class": [
        "Automorphism"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "autm_3d",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "object": "autm_3d",
      "file": "autm_3d.rda",
      "class": [
        "Automorphism"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "autm_z125",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "object": "autm_z125",
      "file": "autm_z125.rda",
      "class": [
        "Automorphism"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "brca1_aln",
      "title": "Multiple Sequence Alignment (MSA) of Primate BRCA1 DNA repair genes.",
      "object": "brca1_aln",
      "file": "brca1_aln.rda",
      "class": [
        "DNAMultipleAlignment"
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      "fields": [],
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    },
    {
      "name": "brca1_aln2",
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      "object": "brca1_aln2",
      "file": "brca1_aln2.rda",
      "class": [
        "DNAMultipleAlignment"
      ],
      "fields": [],
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      "tojson": false
    },
    {
      "name": "brca1_autm",
      "title": "Automorphisms between DNA Sequences from Primate BRCA1 Genes",
      "object": "brca1_autm",
      "file": "brca1_autm.rda",
      "class": [
        "AutomorphismList"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "brca1_autm2",
      "title": "Automorphisms between DNA Sequences from Primate BRCA1 Genes",
      "object": "brca1_autm2",
      "file": "brca1_autm2.rda",
      "class": [
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      ],
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      "tojson": false
    },
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      "file": "cdm_z64.rda",
      "class": [
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      ],
      "fields": [],
      "table": true,
      "tojson": true
    },
    {
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      "class": [
        "DNAMultipleAlignment"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "covid_autm",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "object": "covid_autm",
      "file": "covid_autm.rda",
      "class": [
        "Automorphism"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "cyc_aln",
      "title": "Multiple Sequence Alignment (MSA) of Primate Somatic Cytochrome C",
      "object": "cyc_aln",
      "file": "cyc_aln.rda",
      "class": [
        "DNAMultipleAlignment"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "cyc_autm",
      "title": "Automorphisms between DNA Sequences from Primate Cytochrome C Genes",
      "object": "cyc_autm",
      "file": "cyc_autm.rda",
      "class": [
        "AutomorphismList"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "dna_phyche",
      "title": "Some Physicochemical Properties of DNA bases",
      "object": "dna_phyche",
      "file": "dna_phyche.rda",
      "class": [
        "data.frame"
      ],
      "fields": [
        "proton_affinity",
        "partition_coef",
        "dipole_moment",
        "tautomerization_energy"
      ],
      "rows": 4,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "aa_phychem_index",
      "title": "Amino acid mutation matrix",
      "topics": [
        "aa_index",
        "aa_mutmat",
        "aa_phychem_index"
      ]
    },
    {
      "page": "aaindex1",
      "title": "List of 571 Amino Acid Physicochemical Indexes from AAindex Database",
      "topics": [
        "aaindex1"
      ]
    },
    {
      "page": "aaindex2",
      "title": "List of 94 Amino Acid Matrices from AAindex",
      "topics": [
        "aaindex2"
      ]
    },
    {
      "page": "aaindex3",
      "title": "Statistical protein contact potentials matrices from AAindex ver.9.2",
      "topics": [
        "aaindex3"
      ]
    },
    {
      "page": "aln",
      "title": "Simulated 'DNAStringSet' class object",
      "topics": [
        "aln"
      ]
    },
    {
      "page": "aminoacid_dist",
      "title": "Distance Between Aminoacids in Terms of Codon Distance",
      "topics": [
        "aminoacid_dist",
        "aminoacid_dist,AAStringSet,ANY-method",
        "aminoacid_dist,character,character-method",
        "aminoacid_dist,CodonGroup_OR_Automorphisms,ANY-method",
        "aminoacid_dist,DNAStringSet,ANY-method"
      ]
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    {
      "page": "as.AutomorphismList",
      "title": "Methods for AutomorphismList-class Objects",
      "topics": [
        "as.AutomorphismList",
        "as.AutomorphismList,GRangesList,GRanges_OR_NULL-method",
        "as.AutomorphismList,list,GRanges_OR_NULL-method"
      ]
    },
    {
      "page": "aut3D",
      "title": "Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z5^3.",
      "topics": [
        "aut3D"
      ]
    },
    {
      "page": "autby_coef",
      "title": "Automorphisms between DNA Primate BRCA1 Genes Grouped by Coefficients",
      "topics": [
        "autby_coef"
      ]
    },
    {
      "page": "autm",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "topics": [
        "autm"
      ]
    },
    {
      "page": "autm_3d",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "topics": [
        "autm_3d"
      ]
    },
    {
      "page": "autm_z125",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "topics": [
        "autm_z125"
      ]
    },
    {
      "page": "automorphism_bycoef",
      "title": "Autmorphism Grouping by Coefficient",
      "topics": [
        "automorphism_bycoef",
        "automorphism_bycoef,Automorphism-method",
        "automorphism_bycoef,AutomorphismList-method"
      ]
    },
    {
      "page": "automorphism_prob",
      "title": "Autmorphism Probability",
      "topics": [
        "automorphism_prob",
        "automorphism_prob,AutomorphismByCoef-method",
        "automorphism_prob,AutomorphismByCoefList-method"
      ]
    },
    {
      "page": "automorphismByRanges",
      "title": "Get the automorphisms by ranges.",
      "topics": [
        "automorphismByRanges",
        "automorphismByRanges,Automorphism-method",
        "automorphismByRanges,AutomorphismList-method"
      ]
    },
    {
      "page": "automorphisms",
      "title": "Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in a Given Abelian group.",
      "topics": [
        "automorphisms",
        "automorphisms,DNAStringSet_OR_NULL-method"
      ]
    },
    {
      "page": "autZ125",
      "title": "Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z125.",
      "topics": [
        "autZ125"
      ]
    },
    {
      "page": "autZ5",
      "title": "Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z5.",
      "topics": [
        "autZ5"
      ]
    },
    {
      "page": "autZ64",
      "title": "Compute the Automorphisms of Mutational Events Between two Codon Sequences Represented in Z64.",
      "topics": [
        "autZ64"
      ]
    },
    {
      "page": "base_methods",
      "title": "DNA Sequences Methods",
      "topics": [
        "base_coord",
        "base_coord,DNAStringSet_OR_NULL-method",
        "base_matrix",
        "base_matrix,DNAStringSet_OR_NULL-method",
        "base_methods",
        "base_seq2string_set",
        "base_seq2string_set,BaseSeq-method",
        "seq2granges",
        "seq2granges,DNAStringSet_OR_NULL-method"
      ]
    },
    {
      "page": "base2codon",
      "title": "Split a DNA sequence into codons",
      "topics": [
        "base2codon",
        "base2codon,character-method",
        "base2codon,DNAMultipleAlignment-method",
        "base2codon,DNAStringSet-method"
      ]
    },
    {
      "page": "base2int",
      "title": "Replace bases with integers from Z4 and Z5",
      "topics": [
        "base2int",
        "base2int,character-method",
        "base2int,data.frame-method"
      ]
    },
    {
      "page": "brca1_aln",
      "title": "Multiple Sequence Alignment (MSA) of Primate BRCA1 DNA repair genes.",
      "topics": [
        "brca1_aln"
      ]
    },
    {
      "page": "brca1_aln2",
      "title": "Multiple Sequence Alignment (MSA) of Primate BRCA1 DNA repair genes.",
      "topics": [
        "brca1_aln2"
      ]
    },
    {
      "page": "brca1_autm",
      "title": "Automorphisms between DNA Sequences from Primate BRCA1 Genes",
      "topics": [
        "brca1_autm"
      ]
    },
    {
      "page": "brca1_autm2",
      "title": "Automorphisms between DNA Sequences from Primate BRCA1 Genes",
      "topics": [
        "brca1_autm2"
      ]
    },
    {
      "page": "cdm_z64",
      "title": "Codon Distance Matrices for the Standard Genetic Code on Z4",
      "topics": [
        "cdm_z64"
      ]
    },
    {
      "page": "codon_coord",
      "title": "Codon coordinates on a given a given Abelian group representation.",
      "topics": [
        "codon_coord",
        "codon_coord,BaseGroup-method",
        "codon_coord,DNAStringSet_OR_NULL-method",
        "codon_coord,matrix_OR_data_frame-method"
      ]
    },
    {
      "page": "codon_dist",
      "title": "Weighted Manhattan Distance Between Codons",
      "topics": [
        "codon_dist",
        "codon_dist,character-method",
        "codon_dist,CodonGroup_OR_Automorphisms-method",
        "codon_dist,DNAStringSet-method"
      ]
    },
    {
      "page": "codon_dist_matrix",
      "title": "Compute Codon Distance Matrix",
      "topics": [
        "codon_dist_matrix"
      ]
    },
    {
      "page": "codon_matrix",
      "title": "Codon Coordinate Matrix",
      "topics": [
        "codon_matrix",
        "codon_matrix,BaseSeqMatrix-method",
        "codon_matrix,DNAMultipleAlignment-method",
        "codon_matrix,DNAStringSet-method"
      ]
    },
    {
      "page": "conserved_regions",
      "title": "Conserved and Non-conserved Regions from a MSA",
      "topics": [
        "conserved_regions",
        "conserved_regions,Automorphism-method",
        "conserved_regions,AutomorphismByCoef-method",
        "conserved_regions,AutomorphismByCoefList-method",
        "conserved_regions,AutomorphismList-method"
      ]
    },
    {
      "page": "covid_aln",
      "title": "Pairwise Sequence Alignment (MSA) of COVID-19 genomes.",
      "topics": [
        "covid_aln"
      ]
    },
    {
      "page": "covid_autm",
      "title": "Automorphisms between DNA Sequences from two COVID-19 genomes",
      "topics": [
        "covid_autm"
      ]
    },
    {
      "page": "cyc_aln",
      "title": "Multiple Sequence Alignment (MSA) of Primate Somatic Cytochrome C",
      "topics": [
        "cyc_aln"
      ]
    },
    {
      "page": "cyc_autm",
      "title": "Automorphisms between DNA Sequences from Primate Cytochrome C Genes",
      "topics": [
        "cyc_autm"
      ]
    },
    {
      "page": "dna_phyche",
      "title": "Some Physicochemical Properties of DNA bases",
      "topics": [
        "dna_phyche"
      ]
    },
    {
      "page": "dna_phychem",
      "title": "DNA numerical matrix",
      "topics": [
        "dna_phychem",
        "dna_phychem,character-method",
        "dna_phychem,DNAStringSet_OR_DNAMultipleAlignment-method"
      ]
    },
    {
      "page": "get_coord",
      "title": "DNA base/codon sequence and coordinates represented on a given Abelian group.",
      "topics": [
        "get_coord",
        "get_coord,BaseGroup_OR_CodonGroup-method",
        "get_coord,DNAStringSet_OR_NULL-method"
      ]
    },
    {
      "page": "get_mutscore",
      "title": "Get Mutation Score from an AAindex or a Mutation/Distance Matrix",
      "topics": [
        "get_mutscore",
        "get_mutscore,BaseSeq,missing-method",
        "get_mutscore,character,character-method",
        "get_mutscore,DNAMultipleAlignment,missing-method",
        "get_mutscore,DNAStringSet,missing-method"
      ]
    },
    {
      "page": "getAutomorphisms",
      "title": "Get Automorphisms",
      "topics": [
        "getAutomorphisms",
        "getAutomorphisms,AutomorphismList-method",
        "getAutomorphisms,DataFrame_OR_data.frame-method",
        "getAutomorphisms,list-method"
      ]
    },
    {
      "page": "matrices",
      "title": "Get the Coordinate Representation from DNA Sequences on Specified Abelian Group",
      "topics": [
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        "matrices,CodonSeq-method",
        "matrices,DNAStringSet_OR_NULL-method",
        "matrices,MatrixList-method"
      ]
    },
    {
      "page": "mod",
      "title": "Modulo Operation",
      "topics": [
        "'%%'",
        "mod",
        "mod,matrix,numeric-method",
        "modulo"
      ]
    },
    {
      "page": "modlineq",
      "title": "Modular System of Linear Equation Solver (MLE)",
      "topics": [
        "modlineq"
      ]
    },
    {
      "page": "mut_type",
      "title": "Classification of DNA base mutations",
      "topics": [
        "mut_type"
      ]
    },
    {
      "page": "peptide_phychem_index",
      "title": "Amino acid numerical matrix",
      "topics": [
        "peptide_phychem_index",
        "peptide_phychem_index,character-method",
        "peptide_phychem_index,DNAStringSet_OR_DNAMultipleAlignment-method"
      ]
    },
    {
      "page": "seqranges",
      "title": "Get DNA sequence Ranges and Coordinates representation on a given Abelian Group",
      "topics": [
        "seqranges",
        "seqranges,CodonSeq-method",
        "seqranges,DNAStringSet_OR_NULL-method"
      ]
    },
    {
      "page": "slapply",
      "title": "Apply a function over a list-like object preserving its attributes",
      "topics": [
        "slapply"
      ]
    },
    {
      "page": "sortByChromAndStart",
      "title": "Sorting 'GRanges-class' objects",
      "topics": [
        "sortByChromAndEnd",
        "sortByChromAndStart"
      ]
    },
    {
      "page": "str2chr",
      "title": "String to Character",
      "topics": [
        "str2chr",
        "str2chr,character-method",
        "str2chr,list-method"
      ]
    },
    {
      "page": "str2dig",
      "title": "String to Digits",
      "topics": [
        "str2dig",
        "str2dig,character-method",
        "str2dig,list-method"
      ]
    },
    {
      "page": "translation",
      "title": "Translation of DNA/RNA sequences",
      "topics": [
        "translation",
        "translation,BioString-method",
        "translation,character-method"
      ]
    }
  ],
  "_pkglogo": "https://github.com/bioc/GenomAutomorphism/raw/HEAD/man/figures/logo.png",
  "_readme": "https://github.com/bioc/GenomAutomorphism/raw/HEAD/README.md",
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  "_vignettes": [
    {
      "source": "GenomAutomorphism.Rmd",
      "filename": "GenomAutomorphism.html",
      "title": "Get started-with GenomAutomorphism",
      "author": "Robersy Sanchez",
      "engine": "knitr::rmarkdown",
      "headings": [
        "GenomAutomorphism Overview",
        "Installing GenomAutomorphism",
        "Automorphisms",
        "Load the R libraries",
        "Read the alignment FASTA  and encode the sequences",
        "Group representations",
        "\"Dual\" genetic-code cubes",
        "Automorphisms on $\\mathbb{Z}_{64}$",
        "Automorphisms between whole genomes of SARS-CoV-2 related coronaviruses",
        "Bar plot automorphism distribution by cubes",
        "Grouping automorphism by automorphism's coefficients. Types of mutations",
        "Conserved and non-conserved regions",
        "Conserved regions",
        "Automorphisms on $\\mathbb{Z}_{125}$",
        "Automorphisms on the Genetic-code Cube Representation on GF(5)",
        "Grouping automorphism by automorphism's coefficients",
        "References",
        "Session info"
      ],
      "created": "2021-10-24 03:26:05",
      "modified": "2025-07-23 00:06:38",
      "commits": 32
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