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  "Title": "Generating Protein Sequences with Deep Generative Models",
  "Description": "Generative modeling for protein engineering is key to\nsolving fundamental problems in synthetic biology, medicine,\nand material science. Machine learning has enabled us to\ngenerate useful protein sequences on a variety of scales.\nGenerative models are machine learning methods which seek to\nmodel the distribution underlying the data, allowing for the\ngeneration of novel samples with similar properties to those on\nwhich the model was trained. Generative models of proteins can\nlearn biologically meaningful representations helpful for a\nvariety of downstream tasks. Furthermore, they can learn to\ngenerate protein sequences that have not been observed before\nand to assign higher probability to protein sequences that\nsatisfy desired criteria. In this package, common deep\ngenerative models for protein sequences, such as variational\nautoencoder (VAE), generative adversarial networks (GAN), and\nautoregressive models are available. In the VAE and GAN, the\nWord2vec is used for embedding. The transformer encoder is\napplied to protein sequences for the autoregressive model.",
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  "Date": "2024-02-06",
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  "Date/Publication": "2026-05-29 18:37:14 UTC",
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