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  "Title": "Gene Set Variation Analysis for Microarray and RNA-Seq Data",
  "Authors@R": "c(person(\"Robert\", \"Castelo\", role=c(\"aut\", \"cre\"),\ncomment=c(ORCID=\"0000-0003-2229-4508\"),\nemail=\"robert.castelo@upf.edu\"),\nperson(\"Justin\", \"Guinney\", role=\"aut\", email=\"jguinney@gmail.com\"),\nperson(\"Alexey\", \"Sergushichev\", role=\"ctb\", email=\"alsergbox@gmail.com\"),\nperson(\"Pablo Sebastian\", \"Rodriguez\", role=\"ctb\", email=\"pablo.rodriguez.bio2@gmail.com\"),\nperson(\"Axel\", \"Klenk\", role=\"ctb\", email=\"axel.klenk@gmail.com\"),\nperson(\"Chan Zuckerberg Initiative (CZI)\", role=\"fnd\"),\nperson(\"Spanish Ministry of Science, Innovation and Universities (MCIU)\", role=\"fnd\"))",
  "Description": "Gene Set Variation Analysis (GSVA) is a non-parametric,\nunsupervised method for estimating variation of gene set\nenrichment through the samples of a expression data set. GSVA\nperforms a change in coordinate systems, transforming the data\nfrom a gene by sample matrix to a gene-set by sample matrix,\nthereby allowing the evaluation of pathway enrichment for each\nsample. This new matrix of GSVA enrichment scores facilitates\napplying standard analytical methods like functional\nenrichment, survival analysis, clustering, CNV-pathway analysis\nor cross-tissue pathway analysis, in a pathway-centric manner.",
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  "Date/Publication": "2026-07-03 15:16:02 UTC",
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  "Author": "Robert Castelo [aut, cre] (ORCID:\n<https://orcid.org/0000-0003-2229-4508>),\nJustin Guinney [aut],\nAlexey Sergushichev [ctb],\nPablo Sebastian Rodriguez [ctb],\nAxel Klenk [ctb],\nChan Zuckerberg Initiative (CZI) [fnd],\nSpanish Ministry of Science, Innovation and Universities (MCIU) [fnd]",
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    "geneSetSizes",
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    "gsvaScores",
    "guessGeneIdType",
    "igsva",
    "loadHDF5GSVA",
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    "plageParam",
    "readGMT",
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    "saveHDF5GSVAranks",
    "spatCor",
    "ssgseaParam",
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      "page": "computeGeneSetsOverlap",
      "title": "Compute gene-sets overlap",
      "topics": [
        "computeGeneSetsOverlap",
        "computeGeneSetsOverlap,GeneSetCollection,character-method",
        "computeGeneSetsOverlap,list,character-method"
      ]
    },
    {
      "page": "deduplicateGeneSets",
      "title": "Handling of Duplicated Gene Set Names",
      "topics": [
        "deduplicateGeneSets"
      ]
    },
    {
      "page": "filterGeneSets",
      "title": "Filter gene sets",
      "topics": [
        "filterGeneSets",
        "filterGeneSets,GeneSetCollection-method",
        "filterGeneSets,list-method"
      ]
    },
    {
      "page": "geneIdsToGeneSetCollection",
      "title": "Construct a GeneSetCollection object from a list of character vectors",
      "topics": [
        "geneIdsToGeneSetCollection"
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    },
    {
      "page": "geneSets",
      "title": "Retrieve or Determine Gene Sets",
      "topics": [
        "geneSets",
        "geneSets,GsvaExprData-method",
        "geneSets,GsvaMethodParam-method",
        "geneSets,SingleCellExperiment-method",
        "geneSets,SpatialExperiment-method",
        "geneSets,SummarizedExperiment-method",
        "geneSetSizes",
        "geneSetSizes,GsvaExprData-method",
        "geneSetSizes,GsvaMethodParam-method"
      ]
    },
    {
      "page": "gsva",
      "title": "Gene Set Variation Analysis",
      "topics": [
        "gsva",
        "gsva,gsvaParam-method",
        "gsva,plageParam-method",
        "gsva,ssgseaParam-method",
        "gsva,zscoreParam-method"
      ]
    },
    {
      "page": "gsvaAnnotation",
      "title": "Store and Retrieve Annotation Metadata",
      "topics": [
        "gsvaAnnotation",
        "gsvaAnnotation,ExpressionSet-method",
        "gsvaAnnotation,GeneSetCollection-method",
        "gsvaAnnotation,GsvaExprData-method",
        "gsvaAnnotation,list-method",
        "gsvaAnnotation,SingleCellExperiment-method",
        "gsvaAnnotation,SpatialExperiment-method",
        "gsvaAnnotation,SummarizedExperiment-method",
        "gsvaAnnotation<-",
        "gsvaAnnotation<-,ExpressionSet,character-method",
        "gsvaAnnotation<-,ExpressionSet,GeneIdentifierType-method",
        "gsvaAnnotation<-,GsvaExprData,GeneIdentifierType-method",
        "gsvaAnnotation<-,list,GeneIdentifierType-method",
        "gsvaAnnotation<-,SingleCellExperiment,GeneIdentifierType-method",
        "gsvaAnnotation<-,SpatialExperiment,GeneIdentifierType-method",
        "gsvaAnnotation<-,SummarizedExperiment,GeneIdentifierType-method"
      ]
    },
    {
      "page": "gsvaEnrichment",
      "title": "GSVA enrichment data and visualization",
      "topics": [
        "gsvaEnrichment"
      ]
    },
    {
      "page": "GsvaExprData-class",
      "title": "'GsvaExprData' class",
      "topics": [
        "GsvaExprData",
        "GsvaExprData-class"
      ]
    },
    {
      "page": "GsvaGeneSets-class",
      "title": "'GsvaGeneSets' class",
      "topics": [
        "GsvaGeneSets-class"
      ]
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    {
      "page": "map-reduce",
      "title": "MapReduce parallelization for HPC environments",
      "topics": [
        "gsvaBatchtoolsSlurmParam",
        "gsvaMap",
        "gsvaReduce"
      ]
    },
    {
      "page": "GsvaMethodParam-class",
      "title": "'GsvaMethodParam' class",
      "topics": [
        "details,GsvaMethodParam-method",
        "details,gsvaParam-method",
        "details,ssgseaParam-method",
        "GsvaMethodParam-class"
      ]
    },
    {
      "page": "gsvaParam-class",
      "title": "'gsvaParam' class",
      "topics": [
        "anyNA,gsvaParam-method",
        "geneSets<-",
        "geneSets<-,gsvaParam,GsvaGeneSets-method",
        "gsvaParam",
        "gsvaParam-class",
        "gsvaRanksParam-class"
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    },
    {
      "page": "gsvaRanks",
      "title": "GSVA ranks and scores",
      "topics": [
        "gsvaColRanks",
        "gsvaColScores",
        "gsvaRowNorm"
      ]
    },
    {
      "page": "guessGeneIdType",
      "title": "Guess the gene identifier type from a list of character vectors",
      "topics": [
        "guessGeneIdType"
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    {
      "page": "igsva",
      "title": "Gene Set Variation Analysis",
      "topics": [
        "igsva"
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      "title": "'plageParam' class",
      "topics": [
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        "plageParam-class"
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      "title": "Import Gene Sets from a GMT File",
      "topics": [
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      ]
    },
    {
      "page": "gsva-serialization",
      "title": "Save/load GSVA output to disk using HDF5 format",
      "topics": [
        "loadHDF5GSVA",
        "saveHDF5GSVA"
      ]
    },
    {
      "page": "spatCor",
      "title": "Compute Spatial Autocorrelation for SpatialExperiment objects",
      "topics": [
        "spatCor",
        "spatCor,SpatialExperiment-method"
      ]
    },
    {
      "page": "ssgseaParam-class",
      "title": "'ssgseaParam' class",
      "topics": [
        "anyNA,ssgseaParam-method",
        "ssgseaParam",
        "ssgseaParam-class"
      ]
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    {
      "page": "zscoreParam-class",
      "title": "'zscoreParam' class",
      "topics": [
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        "zscoreParam-class"
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