{ "_id": "6a1ad2161d7bb097a09e2cd2", "Package": "G4SNVHunter", "Type": "Package", "Title": "Evaluating SNV-Induced Disruption of G-Quadruplex Structures", "Version": "1.5.0", "Authors@R": "person(given = \"Rongxin\", \nfamily = \"Zhang\",\nemail = \"rongxinzhang@outlook.com\",\nrole = c(\"cre\", \"aut\"),\ncomment = c('ORCID' = \"0000-0002-1643-1185\"))", "Description": "G-quadruplexes (G4s) are unique nucleic acid secondary\nstructures predominantly found in guanine-rich regions and have\nbeen shown to be involved in various biological regulatory\nprocesses. G4SNVHunter is an R package designed to rapidly\nidentify genomic sequences with G4-forming propensity and to\naccurately screen user-provided single nucleotide variants—as\nwell as other small-scale variants such as indels and MNVs—for\ntheir potential to destabilize these structures. This allows\nresearchers to then screen these critical variants for deeper\nstudy, digging into how they might influence biological\nfunctions—think gene regulation, for instance—by impairing G4\nformation propensity.", "Encoding": "UTF-8", "LazyData": "false", "RoxygenNote": "7.3.2", "License": "MIT + file LICENSE", "VignetteBuilder": "knitr", "biocViews": "Epigenetics, SNP", "News": "NEWS.md", "URL": "https://github.com/rongxinzh/G4SNVHunter", "BugReports": "https://github.com/rongxinzh/G4SNVHunter/issues", "Config/testthat/edition": "3", "Config/pak/sysreqs": "make libbz2-dev libicu-dev liblzma-dev libpng-dev\nlibxml2-dev libssl-dev xz-utils zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 13:04:05 UTC", "RemoteUrl": "https://github.com/bioc/G4SNVHunter", "RemoteRef": "HEAD", "RemoteSha": "0457e3ea3dc6a156136ddc8c28ee88037d7f3e66", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-05-30 08:22:45 UTC", "User": "root" }, "Author": "Rongxin 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