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  "Date": "2017-07-23",
  "Title": "DEsubs: an R package for flexible identification of\ndifferentially expressed subpathways using RNA-seq expression\nexperiments",
  "Author": "Aristidis G. Vrahatis and Panos Balomenos",
  "Maintainer": "Aristidis G. Vrahatis <agvrahatis@upatras.gr>, Panos\nBalomenos <balomenos@upatras.gr>",
  "Description": "DEsubs is a network-based systems biology package that\nextracts disease-perturbed subpathways within a pathway network\nas recorded by RNA-seq experiments. It contains an extensive\nand customizable framework covering a broad range of operation\nmodes at all stages of the subpathway analysis, enabling a\ncase-specific approach. The operation modes refer to the\npathway network construction and processing, the subpathway\nextraction, visualization and enrichment analysis with regard\nto various biological and pharmacological features. Its\ncapabilities render it a tool-guide for both the modeler and\nexperimentalist for the identification of more robust\nsystems-level biomarkers for complex diseases.",
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