{
  "_id": "6ac61d5cf511ae58c09a653d",
  "Package": "ChIPseeker",
  "Type": "Package",
  "Title": "ChIPseeker for ChIP peak Annotation, Comparison, and\nVisualization",
  "Version": "1.49.3",
  "Authors@R": "c( \nperson(given = \"Guangchuang\", family = \"Yu\",       email = \"guangchuangyu@gmail.com\",      role  = c(\"aut\", \"cre\"), comment = c(ORCID = \"0000-0002-6485-8781\")),\nperson(given = \"Ming\",        family = \"Li\",       email = \"limiang929@gmail.com\",         role = \"ctb\"),\nperson(given = \"Qianwen\",     family = \"Wang\",     email = \"treywea@gmail.com\",            role = \"ctb\"),\nperson(given = \"Yun\",         family = \"Yan\",      email = \"youryanyun@gmail.com\",         role = \"ctb\"),\nperson(given = \"Hervé\",       family = \"Pagès\",    email = \"hpages.on.github@gmail.com\",   role  = \"ctb\"),\nperson(given = \"Michael\",     family = \"Kluge\",    email = \"michael.kluge@bio.ifi.lmu.de\", role  = \"ctb\"),\nperson(given = \"Thomas\",      family = \"Schwarzl\", email = \"schwarzl@embl.de\",             role  = \"ctb\"),\nperson(given = \"Zhougeng\",    family = \"Xu\",       email = \"xuzhougeng@163.com\",           role  = \"ctb\"),\nperson(given = \"Chun-Hui\",    family = \"Gao\",      email=\"gaospecial@gmail.com\",           role  = \"ctb\", comment=c(ORCID = \"0000-0002-1445-7939\"))\n)",
  "Maintainer": "Guangchuang Yu <guangchuangyu@gmail.com>",
  "Description": "This package implements functions to retrieve the nearest\ngenes around the peak, annotate genomic region of the peak,\nstatstical methods for estimate the significance of overlap\namong ChIP peak data sets, and incorporate GEO database for\nuser to compare the own dataset with those deposited in\ndatabase. The comparison can be used to infer cooperative\nregulation and thus can be used to generate hypotheses. Several\nvisualization functions are implemented to summarize the\ncoverage of the peak experiment, average profile and heatmap of\npeaks binding to TSS regions, genomic annotation, distance to\nTSS, and overlap of peaks or genes.",
  "Remotes": [
    "GuangchuangYu/enrichplot"
  ],
  "URL": "https://yulab-smu.top/contribution-knowledge-mining/",
  "BugReports": "https://github.com/YuLab-SMU/ChIPseeker/issues",
  "Encoding": "UTF-8",
  "VignetteBuilder": "knitr",
  "ByteCompile": "true",
  "License": "Artistic-2.0",
  "biocViews": "Annotation, ChIPSeq, Software, Visualization,\nMultipleComparison",
  "Config/roxygen2/version": "8.1.0",
  "Config/pak/sysreqs": "libcairo2-dev cmake libfontconfig1-dev\nlibfreetype6-dev libglpk-dev make libbz2-dev libicu-dev\nliblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev\nxz-utils zlib1g-dev",
  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-10-05 10:09:17 UTC",
  "RemoteUrl": "https://github.com/bioc/ChIPseeker",
  "RemoteRef": "HEAD",
  "RemoteSha": "df67ad44b3d5772439fb74d6c66fb6751bc14e7a",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-10-07 08:46:41 UTC",
    "User": "root"
  },
  "Author": "Guangchuang Yu [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-6485-8781>),\nMing Li [ctb],\nQianwen Wang [ctb],\nYun Yan [ctb],\nHervé Pagès [ctb],\nMichael Kluge [ctb],\nThomas Schwarzl [ctb],\nZhougeng Xu [ctb],\nChun-Hui Gao [ctb] (ORCID: <https://orcid.org/0000-0002-1445-7939>)",
  "_user": "bioc",
  "_type": "src",
  "_file": "ChIPseeker_1.49.3.tar.gz",
  "_fileid": "https://r2.ropensci.org/12fb6981452eaa5daf2beaa44f5dd801846642525e29466bd031fca04be8c7df",
  "_filesize": 9067025,
  "_sha256": "12fb6981452eaa5daf2beaa44f5dd801846642525e29466bd031fca04be8c7df",
  "_expires": "2027-01-15T10:22:17.000Z",
  "_created": "2026-10-07T08:46:41.000Z",
  "_published": "2026-10-07T10:22:19.976Z",
  "_buildurl": "https://github.com/r-universe/bioc/actions/runs/37593581562",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_bioccheck": {
    "error": 2,
    "warning": 4,
    "note": 15
  },
  "_upstream": "https://github.com/bioc/ChIPseeker",
  "_commit": {
    "id": "df67ad44b3d5772439fb74d6c66fb6751bc14e7a",
    "author": "Guangchuang Yu <guangchuangyu@gmail.com>",
    "committer": "Guangchuang Yu <guangchuangyu@gmail.com>",
    "message": "handle an empty peak set instead of failing with unrelated errors\n\nannotatePeak(GRanges(), TxDb = txdb) failed with \"Error: invalid subscript\"\nand, with addFlankGeneInfo, with \"replacement has 1 row, data has 0\".\n\nRoot cause is the same as in #238: for an empty query follow()/precede()\nreturn a SortedByQueryHits object rather than indices, which is not a valid row\nsubscript. getNearestFeatureIndicesAndDistances() now returns empty index,\ndistance and peak vectors in that case, and annotatePeak() returns an empty\ncsAnno (0 rows, peakNum 0, empty detailGenomicAnnotation and annoStat) before\nthe steps that are not defined for zero peaks. seq2gene() returns\ncharacter(0) for an empty input as a result of the same guard.\n\nCovered for the plain call and for addFlankGeneInfo + annoDb.\n",
    "time": 1791194957
  },
  "_maintainer": {
    "name": "Guangchuang Yu",
    "email": "guangchuangyu@gmail.com",
    "login": "guangchuangyu",
    "twitter": "@guangchuangyu",
    "description": "Professor of Bioinformatics at Southern Medical University.",
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  "_devurl": "https://github.com/yulab-smu/chipseeker",
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  "_homeurl": "https://github.com/yulab-smu/chipseeker",
  "_realowner": "bioc",
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  "_exports": [
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    "annotatePeak",
    "as.GRanges",
    "combine_csAnno",
    "covplot",
    "downloadGEObedFiles",
    "downloadGSMbedFiles",
    "dropAnno",
    "enrichAnnoOverlap",
    "enrichPeakOverlap",
    "getAnnoStat",
    "getBioRegion",
    "getGEOgenomeVersion",
    "getGEOInfo",
    "getGEOspecies",
    "getPromoters",
    "getSampleFiles",
    "getTagMatrix",
    "GRangesList",
    "makeBioRegionFromGranges",
    "overlap",
    "peak_Profile_Heatmap",
    "peakHeatmap",
    "peakHeatmap_multiple_Sets",
    "plotAnnoBar",
    "plotAnnoPie",
    "plotAnnoPie.csAnno",
    "plotAvgProf",
    "plotAvgProf2",
    "plotDistToTSS",
    "plotPeakProf",
    "plotPeakProf2",
    "readPeakFile",
    "rel",
    "seq2gene",
    "show",
    "shuffle",
    "tagHeatmap",
    "upsetplot",
    "vennpie",
    "vennplot",
    "vennplot.peakfile"
  ],
  "_datasets": [
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      "name": "gsminfo",
      "title": "Information Datasets",
      "object": "gsminfo",
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      "class": [
        "data.frame"
      ],
      "fields": [
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        "gsm",
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        "title",
        "characteristics",
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      "table": true,
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      "class": [
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      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "ucsc_release",
      "title": "Information Datasets",
      "object": "ucsc_release",
      "file": "ucsc_release.rda",
      "class": [
        "data.frame"
      ],
      "fields": [
        "species",
        "ucsc_version",
        "release_date",
        "release_name"
      ],
      "rows": 112,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "ChIPseeker-package",
      "title": "ChIPseeker: ChIP peak Annotation, Comparison, and Visualization",
      "topics": [
        "ChIPseeker-package",
        "ChIPseeker"
      ]
    },
    {
      "page": "dotFun",
      "title": ".",
      "topics": [
        "."
      ]
    },
    {
      "page": "dot-ChIPseekerEnv",
      "title": "Initialize and manage ChIPseeker cache environment",
      "topics": [
        ".ChIPseekerEnv"
      ]
    },
    {
      "page": "annotatePeak",
      "title": "Annotate peaks with genomic features",
      "topics": [
        "annotatePeak"
      ]
    },
    {
      "page": "arrange.GRanges",
      "title": "Arrange (sort) GRanges objects using dplyr syntax",
      "topics": [
        "arrange.GRanges"
      ]
    },
    {
      "page": "as.data.frame.csAnno",
      "title": "Convert csAnno object to data.frame",
      "topics": [
        "as.data.frame.csAnno"
      ]
    },
    {
      "page": "as.GRanges",
      "title": "Convert csAnno object to GRanges",
      "topics": [
        "as.GRanges"
      ]
    },
    {
      "page": "combine_csAnno",
      "title": "Combine multiple csAnno objects",
      "topics": [
        "combine_csAnno"
      ]
    },
    {
      "page": "covplot",
      "title": "Plot peak coverage across chromosomes",
      "topics": [
        "covplot"
      ]
    },
    {
      "page": "csAnno-class",
      "title": "Class \"csAnno\"",
      "topics": [
        "csAnno-class",
        "plotAnnoBar,csAnno-method",
        "plotAnnoPie,csAnno-method",
        "plotDistToTSS,csAnno-method",
        "show,csAnno-method",
        "subset,csAnno-method",
        "upsetplot,csAnno-method",
        "vennpie,csAnno-method"
      ]
    },
    {
      "page": "downloadGEObedFiles",
      "title": "downloadGEObedFiles",
      "topics": [
        "downloadGEObedFiles"
      ]
    },
    {
      "page": "downloadGSMbedFiles",
      "title": "downloadGSMbedFiles",
      "topics": [
        "downloadGSMbedFiles"
      ]
    },
    {
      "page": "dropAnno",
      "title": "dropAnno",
      "topics": [
        "dropAnno"
      ]
    },
    {
      "page": "enrichAnnoOverlap",
      "title": "Calculate overlap significance of ChIP experiments based on nearest gene annotation",
      "topics": [
        "enrichAnnoOverlap"
      ]
    },
    {
      "page": "enrichPeakOverlap",
      "title": "Calculate overlap significance of ChIP experiments based on genomic coordinates",
      "topics": [
        "enrichPeakOverlap"
      ]
    },
    {
      "page": "filter.GRanges",
      "title": "Filter GRanges objects using dplyr syntax",
      "topics": [
        "filter.GRanges"
      ]
    },
    {
      "page": "getAnnoStat",
      "title": "Get annotation statistics from csAnno object",
      "topics": [
        "getAnnoStat"
      ]
    },
    {
      "page": "getBioRegion",
      "title": "Prepare a biological region of selected feature from TxDb",
      "topics": [
        "getBioRegion"
      ]
    },
    {
      "page": "getGeneAnno",
      "title": "Get gene annotation from annotation database",
      "topics": [
        "getGeneAnno"
      ]
    },
    {
      "page": "getGEOgenomeVersion",
      "title": "getGEOgenomeVersion",
      "topics": [
        "getGEOgenomeVersion"
      ]
    },
    {
      "page": "getGEOInfo",
      "title": "getGEOInfo",
      "topics": [
        "getGEOInfo"
      ]
    },
    {
      "page": "getGEOspecies",
      "title": "getGEOspecies",
      "topics": [
        "getGEOspecies"
      ]
    },
    {
      "page": "getNearestFeatureIndicesAndDistances",
      "title": "Get index of nearest features to peaks and calculate distances",
      "topics": [
        "getNearestFeatureIndicesAndDistances"
      ]
    },
    {
      "page": "getPromoters",
      "title": "Prepare promoter regions from TxDb",
      "topics": [
        "getPromoters"
      ]
    },
    {
      "page": "getSampleFiles",
      "title": "Get sample peak files included in the package",
      "topics": [
        "getSampleFiles"
      ]
    },
    {
      "page": "getTagMatrix",
      "title": "Calculate tag matrix for peak coverage visualization",
      "topics": [
        "getTagMatrix"
      ]
    },
    {
      "page": "getTagMatrix.binning.internal",
      "title": "Calculate tag matrix using binning method (internal function)",
      "topics": [
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      ]
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      "source": "ChIPseeker.Rmd",
      "filename": "ChIPseeker.html",
      "title": "ChIPseeker: an R package for ChIP peak Annotation, Comparison and Visualization",
      "author": "Guangchuang Yu School of Basic Medical Sciences, Southern Medical University",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Abstract",
        "Citation",
        "Introduction",
        "ChIP profiling",
        "ChIP peaks coverage plot",
        "Profile of ChIP peaks binding to TSS regions",
        "Heatmap of ChIP binding to TSS regions",
        "Average Profile of ChIP peaks binding to TSS region",
        "Profile of ChIP peaks binding to different regions",
        "Binning method for profile of ChIP peaks binding to TSS regions",
        "Profile of ChIP peaks binding to body regions",
        "Profile of ChIP peaks binding to TTS regions",
        "Peak Annotation",
        "Visualize Genomic Annotation",
        "Visualize distribution of TF-binding loci relative to TSS",
        "Functional enrichment analysis",
        "ChIP peak data set comparison",
        "Profile of several ChIP peak data binding to TSS region",
        "Average profiles",
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        "ChIP peak annotation comparision",
        "Functional profiles comparison",
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        "Peak overlap enrichment analysis",
        "Data Mining with ChIP seq data deposited in GEO",
        "GEO data collection",
        "Download GEO ChIP data sets",
        "Overlap significant testing",
        "Need helps?",
        "Session Information",
        "References"
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      "created": "2015-05-17 08:47:21",
      "modified": "2026-09-08 02:18:27",
      "commits": 44
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