{ "_id": "6a1ad75a1d7bb097a09e62ec", "Package": "CNVPanelizer", "Type": "Package", "Title": "Reliable CNV detection in targeted sequencing applications", "Version": "1.45.0", "Date": "2023-03-28", "Authors@R": "c(\nperson(\"Cristiano\", \"Oliveira\", email = \"tanovsky@gmail.com\", role = c(\"aut\")),\nperson(\"Thomas\", \"Wolf\", email = \"thomas_wolf71@gmx.de\", role = c(\"aut\", \"cre\")),\nperson(\"Albrecht\", \"Stenzinger\", email = \"albrecht.stenzinger@med.uni-heidelberg.de\", role = c(\"ctb\")),\nperson(\"Volker\", \"Endris\", email = \"volker.endris@med.uni-heidelberg.de\", role = c(\"ctb\")),\nperson(\"Nicole\", \"Pfarr\", email = \"nicole.pfarr@med.uni-heidelberg.de\", role = c(\"ctb\")),\nperson(\"Benedikt\", \"Brors\", email = \"b.brors@dkfz.de\", role = c(\"ths\")),\nperson(\"Wilko\", \"Weichert\", email = \"wilko.weichert@med.uni-heidelberg.de\", role = c(\"ths\")))", "Description": "A method that allows for the use of a collection of\nnon-matched normal tissue samples. Our approach uses a\nnon-parametric bootstrap subsampling of the available reference\nsamples to estimate the distribution of read counts from\ntargeted sequencing. As inspired by random forest, this is\ncombined with a procedure that subsamples the amplicons\nassociated with each of the targeted genes. The obtained\ninformation allows us to reliably classify the copy number\naberrations on the gene level.", "License": "GPL-3", "LazyData": "false", "biocViews": "Classification, Sequencing, Normalization,\nCopyNumberVariation, Coverage", "VignetteBuilder": "knitr", "NeedsCompilation": "no", "Config/pak/sysreqs": "cmake make libbz2-dev libicu-dev liblzma-dev\nlibuv1-dev libssl-dev xz-utils zlib1g-dev", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-04-28 12:41:28 UTC", "RemoteUrl": "https://github.com/bioc/CNVPanelizer", "RemoteRef": "HEAD", "RemoteSha": "f1d71f9de0a14689a021df66775dd5dc06b5f6eb", "Packaged": { "Date": "2026-05-30 08:51:26 UTC", "User": "root" }, "Author": "Cristiano Oliveira [aut],\nThomas Wolf [aut, cre],\nAlbrecht Stenzinger [ctb],\nVolker Endris [ctb],\nNicole Pfarr [ctb],\nBenedikt Brors [ths],\nWilko Weichert [ths]", "Maintainer": "Thomas Wolf ", "MD5sum": "aa0004268e221e09ac924b8a0d94cb95", "_user": "bioc", "_type": "src", "_file": 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