{ "_id": "6a3735e23efcd9bda44164b9", "Package": "CLAMP", "Type": "Package", "Title": "Curated Latent-variable Analysis with Molecular Priors", "Version": "0.99.3", "Authors@R": "c(\nperson(\"Marc\", \"Subirana-Granes\", role = c(\"aut\",\"cre\"),\nemail = \"mb2subi@gmail.com\",\ncomment = c(ORCID = \"0000-0003-3934-839X\")),\nperson(\"Maria\", \"Chikina\", role = \"aut\",\nemail = \"mchikina@gmail.com\"),\nperson(\"National Human Genome Research Institute\", role = \"fnd\",\ncomment = \"R00 HG011898 to M.P.; R01 HG009299-6A1 to M.C.\"),\nperson(\"Eunice Kennedy Shriver National Institute of Child Health and Human Development\",\nrole = \"fnd\",\ncomment = \"R01 HD109765 to M.P.\"),\nperson(\"National Science Foundation\", role = \"fnd\",\ncomment = \"NSF 2238125 to M.C.\"),\nperson(\"National Eye Institute\", role = \"fnd\",\ncomment = \"NIH R01 EY030546-01A1 to M.C.\")\n)", "Description": "CLAMP performs prior-informed latent variable\ndecomposition of high-dimensional transcriptomic data. It\nintegrates curated gene sets to learn biologically\ninterpretable latent variables, supports file-backed matrices\nfor large datasets, and provides tools for preprocessing,\nnormalization, projection, and evaluation of latent structures.\nCLAMP is designed to scale to tens of thousands of samples,\nmaking it suitable for large public resources such as recount3\nand ARCHS4. It enables researchers to uncover biologically\nmeaningful patterns that connect genes, pathways, and complex\ntraits in transcriptomics studies.", "License": "GPL-3", "URL": "https://chikinalab.github.io/CLAMP/,\nhttps://github.com/chikinalab/CLAMP", "BugReports": "https://github.com/chikinalab/CLAMP/issues", "VignetteBuilder": "knitr", "biocViews": "Software, GeneExpression, RNASeq, Transcriptomics,\nDimensionReduction, Visualization, Normalization, Pathways,\nPreprocessing, GenePrediction, GeneTarget", "Encoding": "UTF-8", "LazyData": "false", "Roxygen": "list(markdown = TRUE)", "Config/testthat/edition": "3", "Config/roxygen2/version": "8.0.0", "RoxygenNote": "7.3.3", "Config/pak/sysreqs": "libpng-dev perl", "Repository": "https://bioc.r-universe.dev", "Date/Publication": "2026-06-08 15:36:17 UTC", "RemoteUrl": "https://github.com/bioc/CLAMP", "RemoteRef": "HEAD", "RemoteSha": "1768d3b1bc1ed9f6c7029ca870f5b013c191aee0", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-06-21 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