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      "title": "BioTIP: an R-package for Characterization of Biological Tipping-Points",
      "author": "Zhezhen Wang, Andrew Goldstein, Yuxi Sun, Biniam Feleke, Qier An, Antonio Feliciano, Ieva Tolkaciovaite, and Xinan H Yang",
      "engine": "knitr::rmarkdown",
      "headings": [
        "[Standard Workflow](#Standard workflow)",
        "[Data Preprocessing](#Data Preprocessing)",
        "[Pre-selection Transcript](#Pre-selection Transcript)",
        "[Network Partition](#Network Partition)",
        "[Identifying putative Critical Transition Signals (CTS) using the DNB Module](#Identifying putative Critical Transition Signals (CTS) using the DNB Module)",
        "[Finding Tipping Point and Evaluating CTS](#Finding Tipping Point and Evaluating CTS)",
        "[Advanced Estimation for Pearson Correlation Coefficient Matrix](#Advanced Estimation for Pearson Correlation Coefficient Matrix)",
        "[Data Preprocessing with Trajectory Building Tools](#Data Preprocessing with Trajectory Building Tools)",
        "[Predicting Tipping Point (Advanced Index of Critical Transition (IC*))](#Predicting Tipping Point (Advanced Index of Critical Transition (IC*)))",
        "[Gene Pre-selection](#Gene Pre-selection)",
        "[Network Partition](#Network Partition2)",
        "[Inferring Tipping Point-Driven Transcription Factors](#Inferring Tipping Point-Driven Transcription Factors)",
        "[Quick Start](#Quick Start)",
        "[Genomic Data Source](#Genomic Data Source)",
        "[Extracting Summary Data](#Extracting Summary Data)",
        "[Loading Data](#Loading Data)",
        "[Prepare GRanges Object](#Prepare GRanges Object)",
        "An Identification of Critical Tipping Point using Bulk RNA-seq###",
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