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  "Package": "BioQC",
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  "Title": "Detect tissue heterogeneity in expression profiles with gene\nsets",
  "Version": "1.41.0",
  "Date": "2021-08-18",
  "Authors@R": "c(\nperson(\"Jitao David\", \"Zhang\", email=\"jitao_david.zhang@roche.com\", role = c(\"cre\", \"aut\")),\nperson(\"Laura\", \"Badi\", role=\"aut\"),\nperson(\"Gregor\", \"Sturm\", email=\"mail@gregor-sturm.de\", role=c(\"aut\")),\nperson(\"Roland\", \"Ambs\", role=\"aut\"),\nperson(\"Iakov\", \"Davydov\", role=\"aut\"))",
  "Description": "BioQC performs quality control of high-throughput\nexpression data based on tissue gene signatures. It can detect\ntissue heterogeneity in gene expression data. The core\nalgorithm is a Wilcoxon-Mann-Whitney test that is optimised for\nhigh performance.",
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  "Repository": "https://bioc.r-universe.dev",
  "Date/Publication": "2026-04-28 12:42:16 UTC",
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  "Author": "Jitao David Zhang [cre, aut],\nLaura Badi [aut],\nGregor Sturm [aut],\nRoland Ambs [aut],\nIakov Davydov [aut]",
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    "as.GmtList",
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    "isValidSignedIndexList",
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    "SignedGenesets",
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    "uniqGenesetsByNamespace",
    "wmwLeadingEdge",
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    },
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      ]
    },
    {
      "page": "BaseIndexList-class",
      "title": "An S4 class to hold a list of indices, with the possibility to specify the offset of the indices. IndexList and SignedIndexList extend this class",
      "topics": [
        "BaseIndexList-class"
      ]
    },
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      "title": "Shannon entropy",
      "topics": [
        "entropy"
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      "title": "Filter a GmtList by size",
      "topics": [
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    },
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      ]
    },
    {
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      "title": "Getting leading-edge indices from a vector",
      "topics": [
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        "getLeadingEdgeIndexFromVector"
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      ]
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      "topics": [
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        "gsSize"
      ]
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      "page": "gsGenes",
      "title": "Gene-set member genes",
      "topics": [
        "gsGenes"
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      "page": "gsName",
      "title": "Gene-set names",
      "topics": [
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      ]
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      "page": "gsNamespace",
      "title": "Gene-set namespaces",
      "topics": [
        "gsNamespace"
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      "page": "setGsNamespace",
      "title": "gsNamespace<- is the synonym of setGsNamespace",
      "topics": [
        "gsNamespace<-"
      ]
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      "page": "hasNamespace",
      "title": "Whether namespace is set",
      "topics": [
        "hasNamespace"
      ]
    },
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        "IndexList,list-method",
        "IndexList,logical-method",
        "IndexList,numeric-method"
      ]
    },
    {
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      "title": "An S4 class to hold a list of integers as indices, with the possibility to specify the offset of the indices",
      "topics": [
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      "title": "Function to validate a GmtList object",
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      "title": "Function to validate an IndexList object",
      "topics": [
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      "page": "isValidSignedGenesets",
      "title": "Function to validate a SignedGenesets object",
      "topics": [
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    },
    {
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      "title": "Function to validate a SignedIndexList object",
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    },
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      "title": "Match genes in a list-like object to a vector of genesymbols",
      "topics": [
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        "matchGenes,character,character-method",
        "matchGenes,character,DGEList-method",
        "matchGenes,character,eSet-method",
        "matchGenes,character,matrix-method",
        "matchGenes,GmtList,character-method",
        "matchGenes,GmtList,DGEList-method",
        "matchGenes,GmtList,eSet-method",
        "matchGenes,GmtList,matrix-method",
        "matchGenes,SignedGenesets,character-method",
        "matchGenes,SignedGenesets,DGEList-method",
        "matchGenes,SignedGenesets,eSet-method",
        "matchGenes,SignedGenesets,matrix-method"
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        "offset,BaseIndexList-method"
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      "title": "Set the offset of an 'IndexList' or a 'SignedIndexList' object",
      "topics": [
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        "offset<-",
        "offset<-,IndexList,numeric-method",
        "offset<-,SignedIndexList,numeric-method"
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      "page": "prettySigNames",
      "title": "Prettify default signature names",
      "topics": [
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    },
    {
      "page": "readCurrentSignatures",
      "title": "Load current BioQC signatures",
      "topics": [
        "readCurrentSignatures"
      ]
    },
    {
      "page": "readGmt",
      "title": "Read in gene-sets from a GMT file",
      "topics": [
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      ]
    },
    {
      "page": "readSignedGmt",
      "title": "Read signed GMT files",
      "topics": [
        "readSignedGmt"
      ]
    },
    {
      "page": "sampleSpecialization",
      "title": "Entropy-based sample specialization",
      "topics": [
        "sampleSpecialization"
      ]
    },
    {
      "page": "setDescAsNamespace",
      "title": "Set gene-set description as namespace",
      "topics": [
        "setDescAsNamespace"
      ]
    },
    {
      "page": "setNamespace",
      "title": "Set the namespace field in each gene-set within a GmtList",
      "topics": [
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    },
    {
      "page": "show-GmtList-method",
      "title": "Show method for GmtList",
      "topics": [
        "show,GmtList-method"
      ]
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    {
      "page": "show-IndexList-method",
      "title": "Show method for IndexList",
      "topics": [
        "show,IndexList-method"
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    },
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      "page": "show-SignedGenesets-method",
      "title": "Show method for SignedGenesets",
      "topics": [
        "show,SignedGenesets-method"
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    },
    {
      "page": "show-SignedIndexList-method",
      "title": "Show method for SignedIndexList",
      "topics": [
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      ]
    },
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