{ "_id": "6a196dafacfb0bcc41deb591", "Package": "ASSIGN", "Type": "Package", "Title": "Adaptive Signature Selection and InteGratioN (ASSIGN)", "Version": "1.49.0", "Date": "2014-10-30", "Author": "Ying Shen, Andrea H. Bild, W. Evan Johnson, and Mumtehena\nRahman", "Authors@R": "c(person(given=\"Ying\", family=\"Shen\", email=\"yshen3@bu.edu\", role=c(\"aut\")),\nperson(given=c(\"Andrea\",\"H.\"), family=\"Bild\", email=\"abild@coh.org\", role=c(\"aut\")),\nperson(given=c(\"W.\", \"Evan\"), family=\"Johnson\", email=\"wej@bu.edu\", role=c(\"aut\"),\ncomment = c(ORCID = \"0000-0002-6247-6595\")),\nperson(given=\"Mumtehena\", family=\"Rahman\", email=\"moom.rahman@utah.edu\", role=c(\"aut\")),\nperson(given=\"David\", family=\"Jenkins\", email=\"dfj@bu.edu\", role=c(\"aut\",\"cre\"),\ncomment = c(ORCID = \"0000-0002-7451-4288\")))", "Maintainer": "Ying Shen , W. Evan Johnson ,\nDavid Jenkins , Mumtehena Rahman\n", "Description": "ASSIGN is a computational tool to evaluate the pathway\nderegulation/activation status in individual patient samples.\nASSIGN employs a flexible Bayesian factor analysis approach\nthat adapts predetermined pathway signatures derived either\nfrom knowledge-based literature or from perturbation\nexperiments to the cell-/tissue-specific pathway signatures.\nThe deregulation/activation level of each context-specific\npathway is quantified to a score, which represents the extent\nto which a patient sample encompasses the pathway\nderegulation/activation signature.", "License": "MIT + file LICENSE", "Encoding": "UTF-8", "LazyData": "true", "biocViews": "Software, GeneExpression, Pathways, Bayesian", "RoxygenNote": "7.1.0", "VignetteBuilder": "knitr", "URL": "https://compbiomed.github.io/ASSIGN/", "BugReports": "https://github.com/compbiomed/ASSIGN/issues", "Config/pak/sysreqs": "libpng-dev libxml2-dev libssl-dev 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