Package: anansi Type: Package Title: Annotation-Based Analysis of Specific Interactions Version: 1.3.0 Authors@R: c( person("Thomaz", "Bastiaanssen", email = "thomazbastiaanssen@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-6891-734X")), person("Thomas", "Quinn", email = "contacttomquinn@gmail.com", role = c("aut"), comment = c(ORCID = "0000-0003-0286-6329")), person("Giulio", "Benedetti", email = "giulio.benedetti@utu.fi", role = c("aut"), comment = c(ORCID = "0000-0002-8732-7692")), person("Tuomas", "Borman", email = "tuomas.v.borman@utu.fi", role = c("aut"), comment = c(ORCID = "0000-0002-8563-8884")), person("Leo", "Lahti", email = "leo.lahti@utu.fi", role = c("aut"), comment = c(ORCID = "0000-0001-5537-637X")) ) Description: Studies including both microbiome and metabolomics data are becoming more common. Often, it would be helpful to integrate both datasets in order to see if they corroborate each others patterns. All vs all association is imprecise and likely to yield spurious associations. This package takes a knowledge-based approach to constrain association search space, only considering metabolite-function pairs that have been recorded in a pathway database. This package also provides a framework to assess differential association. Depends: R (>= 4.5.0) Imports: S7, stats, methods, igraph, Matrix, forcats, S4Vectors, SummarizedExperiment, MultiAssayExperiment, SingleCellExperiment, TreeSummarizedExperiment, rlang, ggplot2, ggforce, patchwork, ggraph, tidygraph Suggests: BiocStyle, dplyr, tidyr, graph, mia, KEGGREST, testthat (>= 3.0.0), knitr, rmarkdown License: GPL-3 Encoding: UTF-8 LazyData: false RoxygenNote: 7.3.3 Config/testthat/edition: 3 biocViews: Microbiome, Metabolomics, Regression, Pathways, KEGG URL: https://github.com/thomazbastiaanssen/anansi, https://thomazbastiaanssen.github.io/anansi BugReports: https://github.com/thomazbastiaanssen/anansi/issues VignetteBuilder: knitr Roxygen: list(markdown = TRUE) Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libicu-dev libuv1-dev libxml2-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:05:41 UTC RemoteUrl: https://github.com/bioc/anansi RemoteRef: HEAD RemoteSha: 536c3f2c5515c4183add08a6db0790d0eeaa6b32 NeedsCompilation: no Packaged: 2026-05-27 06:17:01 UTC; root Author: Thomaz Bastiaanssen [aut, cre] (ORCID: ), Thomas Quinn [aut] (ORCID: ), Giulio Benedetti [aut] (ORCID: ), Tuomas Borman [aut] (ORCID: ), Leo Lahti [aut] (ORCID: ) Maintainer: Thomaz Bastiaanssen