Package: airpart Title: Differential cell-type-specific allelic imbalance Version: 1.21.0 Authors@R: c(person(given = "Wancen", family = "Mu", role = c("aut", "cre"), email = "wancen@live.unc.edu", comment = c(ORCID = "0000-0002-5061-7581")), person(given = "Michael", family = "Love", role = c("aut", "ctb"), comment = c(ORCID = "0000-0001-8401-0545"))) Description: Airpart identifies sets of genes displaying differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. It makes use of a generalized fused lasso with binomial observations of allelic counts to partition cell types by their allelic imbalance. Alternatively, a nonparametric method for partitioning cell types is offered. The package includes a number of visualizations and quality control functions for examining single cell allelic imbalance datasets. License: GPL-2 Depends: R (>= 4.1) Imports: SingleCellExperiment, SummarizedExperiment, S4Vectors, scater, stats, smurf, apeglm (>= 1.13.3), emdbook, mclust, clue, dynamicTreeCut, matrixStats, dplyr, plyr, ggplot2, ComplexHeatmap, forestplot, RColorBrewer, rlang, lpSolve, grid, grDevices, graphics, utils, pbapply Suggests: knitr, rmarkdown, roxygen2 (>= 6.0.0), testthat (>= 3.0.0), gplots, tidyr VignetteBuilder: knitr biocViews: SingleCell, RNASeq, ATACSeq, ChIPSeq, Sequencing, GeneRegulation, GeneExpression, Transcription, TranscriptomeVariant, CellBiology, FunctionalGenomics, DifferentialExpression, GraphAndNetwork, Regression, Clustering, QualityControl Encoding: UTF-8 BugReports: https://github.com/Wancen/airpart/issues URL: https://github.com/Wancen/airpart RoxygenNote: 7.2.3 Config/testthat/edition: 3 Config/pak/sysreqs: libpng-dev perl zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:55:30 UTC RemoteUrl: https://github.com/bioc/airpart RemoteRef: HEAD RemoteSha: 8e271c382d5aac8a6125e0558389063bb759c149 NeedsCompilation: no Packaged: 2026-07-04 05:45:57 UTC; root Author: Wancen Mu [aut, cre] (ORCID: ), Michael Love [aut, ctb] (ORCID: ) Maintainer: Wancen Mu