Package: XINA Type: Package Title: Multiplexes Isobaric Mass Tagged-based Kinetics Data for Network Analysis Version: 1.31.0 biocViews: SystemsBiology, Proteomics, RNASeq, Network Author: Lang Ho Lee and Sasha A. Singh Maintainer: Lang Ho Lee and Sasha A. Singh Authors@R: c(person("Lang Ho", "Lee", email="lhlee@bwh.harvard.edu", role = c("aut", "cre")), person("Sasha", "Singh", email="sasingh@bwh.harvard.edu", role = c("aut"))) Description: The aim of XINA is to determine which proteins exhibit similar patterns within and across experimental conditions, since proteins with co-abundance patterns may have common molecular functions. XINA imports multiple datasets, tags dataset in silico, and combines the data for subsequent subgrouping into multiple clusters. The result is a single output depicting the variation across all conditions. XINA, not only extracts coabundance profiles within and across experiments, but also incorporates protein-protein interaction databases and integrative resources such as KEGG to infer interactors and molecular functions, respectively, and produces intuitive graphical outputs. Copyright: XINA combines multiple quantitative (kinetics) datasets from omics studies into a single input dataset for clustering. Copyright(C)2018 Lang Ho Lee, Arda Halu, Stephanie Morgan, Hiroshi Iwata, Masanori Aikawa, and Sasha A. Singh This program is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, any later version. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with this program. If not, see . - Contact emails: L. Lee, LHLEE@BWH.HARVARD.EDU S. Singh, SASINGH@BWH.HARVARD.EDU M. Aikawa, MAIKAWA@BWH.HARVARD.EDU - Mailing address: Department of Medicine, Cardiovascular Division Center for Interdisciplin ary Cardiovascular Sciences 3 Blackfan Street, 17th Floor Boston, MA 02115 USA License: GPL-3 Imports: mclust, plyr, alluvial, ggplot2, igraph, gridExtra, tools, grDevices, graphics, utils, STRINGdb VignetteBuilder: knitr LazyData: FALSE RoxygenNote: 6.1.1 Encoding: UTF-8 Depends: R (>= 3.5) Suggests: knitr, rmarkdown Date: 2019-01-31 git_url: https://git.bioconductor.org/packages/xina git_branch: master git_last_commit: 897b60b Config/pak/sysreqs: libglpk-dev libpng-dev libxml2-dev libssl-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:48:37 UTC RemoteUrl: https://github.com/bioc/XINA RemoteRef: HEAD RemoteSha: 6b0b4dfde7b1fab2aa00c55623f1cb1985bb86bd NeedsCompilation: no Packaged: 2026-07-15 05:27:34 UTC; root