Package: VarCon Type: Package Title: VarCon: an R package for retrieving neighboring nucleotides of an SNV Version: 1.21.0 Description: VarCon is an R package which converts the positional information from the annotation of an single nucleotide variation (SNV) (either referring to the coding sequence or the reference genomic sequence). It retrieves the genomic reference sequence around the position of the single nucleotide variation. To asses, whether the SNV could potentially influence binding of splicing regulatory proteins VarCon calcualtes the HEXplorer score as an estimation. Besides, VarCon additionally reports splice site strengths of splice sites within the retrieved genomic sequence and any changes due to the SNV. License: GPL-3 Encoding: UTF-8 LazyData: true VignetteBuilder: knitr Imports: methods, stats, IRanges, shiny, shinycssloaders, shinyFiles, ggplot2 Depends: Biostrings, BSgenome, GenomicRanges, R (>= 4.1) Suggests: testthat, knitr, rmarkdown biocViews: FunctionalGenomics, AlternativeSplicing RoxygenNote: 7.1.1 Authors@R: person("Johannes", "Ptok", role = c("aut", "cre"), email = "Johannes.Ptok@posteo.de") Config/pak/sysreqs: cmake make libbz2-dev liblzma-dev libuv1-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:54:30 UTC RemoteUrl: https://github.com/bioc/VarCon RemoteRef: HEAD RemoteSha: b86f75b3dce88e5d10fb9c9c21a38c95075e1bd0 NeedsCompilation: no Packaged: 2026-07-15 05:34:16 UTC; root Author: Johannes Ptok [aut, cre] Maintainer: Johannes Ptok