Package: UMI4Cats Title: UMI4Cats: Processing, analysis and visualization of UMI-4C chromatin contact data Version: 1.23.0 Authors@R: c( person(given = "Mireia", family = "Ramos-Rodriguez", role = c("aut", "cre"), email = "mireiarr9@gmail.com", comment = c(ORCID = "0000-0001-8083-2445")), person(given = "Marc", family = "Subirana-Granes", role = c("aut"), email = "marc.subirana@upf.edu"), person(given = "Lorenzo", family = "Pasquali", role = c("aut"), email = "lorenzo.pasquali@upf.edu")) URL: https://github.com/Pasquali-lab/UMI4Cats Description: UMI-4C is a technique that allows characterization of 3D chromatin interactions with a bait of interest, taking advantage of a sonication step to produce unique molecular identifiers (UMIs) that help remove duplication bias, thus allowing a better differential comparsion of chromatin interactions between conditions. This package allows processing of UMI-4C data, starting from FastQ files provided by the sequencing facility. It provides two statistical methods for detecting differential contacts and includes a visualization function to plot integrated information from a UMI-4C assay. BugReports: https://github.com/Pasquali-lab/UMI4Cats/issues License: Artistic-2.0 Encoding: UTF-8 Depends: R (>= 4.1.0), SummarizedExperiment Imports: magick, cowplot, scales, GenomicRanges, ShortRead, zoo, ggplot2, reshape2, regioneR, IRanges, S4Vectors, dplyr, BSgenome, Biostrings, DESeq2, R.utils, Rsamtools, stringr, Rbowtie2, methods, GenomeInfoDb, GenomicAlignments, RColorBrewer, utils, grDevices, stats, annotate, rlang, GenomicFeatures, BiocFileCache, rappdirs, fda, BiocGenerics Suggests: knitr, rmarkdown, BiocStyle, org.Hs.eg.db, TxDb.Hsapiens.UCSC.hg19.knownGene, BSgenome.Hsapiens.UCSC.hg19, tidyr, testthat biocViews: QualityControl, Preprocessing, Alignment, Normalization, Visualization, Sequencing, Coverage VignetteBuilder: knitr RoxygenNote: 7.3.3 Config/pak/sysreqs: make libmagick++-dev gsfonts libbz2-dev libicu-dev libjpeg-dev liblzma-dev libpng-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:53:22 UTC RemoteUrl: https://github.com/bioc/UMI4Cats RemoteRef: HEAD RemoteSha: b941a86040dc096913850cee61ae960775eb4e81 NeedsCompilation: no Packaged: 2026-07-05 14:01:56 UTC; root Author: Mireia Ramos-Rodriguez [aut, cre] (ORCID: ), Marc Subirana-Granes [aut], Lorenzo Pasquali [aut] Maintainer: Mireia Ramos-Rodriguez