Package: TrajectoryGeometry Title: This Package Discovers Directionality in Time and Pseudo-times Series of Gene Expression Patterns Version: 1.21.0 Authors@R: person(given = "Anna", family = "Laddach", role = c("aut", "cre"), email = "anna.laddach@crick.ac.uk", comment = c(ORCID = "0000-0001-5552-6534")) person(given = "Michael", family = "Shapiro", role = c("aut", "cre"), email = "michael.shapiro@crick.ac.uk", comment = c(ORCID = "0000-0002-2769-9320")) Description: Given a time series or pseudo-times series of gene expression data, we might wish to know: Do the changes in gene expression in these data exhibit directionality? Are there turning points in this directionality. Do different subsets of the data move in different directions? This package uses spherical geometry to probe these sorts of questions. In particular, if we are looking at (say) the first n dimensions of the PCA of gene expression, directionality can be detected as the clustering of points on the (n-1)-dimensional sphere. License: MIT + file LICENSE Encoding: UTF-8 LazyData: true RoxygenNote: 7.3.1 Imports: pracma, rgl, ggplot2, stats, methods Depends: R (>= 4.1) Suggests: dplyr, knitr, RColorBrewer, rmarkdown VignetteBuilder: knitr biocViews: BiologicalQuestion, StatisticalMethod, GeneExpression, SingleCell Config/pak/sysreqs: cmake libfreetype6-dev libglu1-mesa-dev make texlive libpng-dev libuv1-dev libgl1-mesa-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:54:58 UTC RemoteUrl: https://github.com/bioc/TrajectoryGeometry RemoteRef: HEAD RemoteSha: 3cb342384f217afa8d764cd76c18b1b65f4dd62c NeedsCompilation: no Packaged: 2026-07-03 16:16:55 UTC; root Author: Michael Shapiro [aut, cre] (ORCID: ) Maintainer: Michael Shapiro