Package: TiDEomics Title: Time-course Differential Expression analysis of omics data Version: 0.99.6 Date: 2026-10-27 Authors@R: person("Tianen", "He", email = "tianen.he@ndm.ox.ac.uk", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-6864-0723")) Description: TiDEomics provides an integrated workflow for multi-group time-course omics data analysis. It uses model-based differential expression, variance decomposition, and co-expression module analysis with WGCNA to characterise temporal, group, and group-specific temporal effects. Multi-dataset and multi-omics comparisons and consensus module identification can be performed using shared features. The package includes quality control, data processing, functional enrichment, and integrated visualisation. It supports data with missing values, and operates on SummarizedExperiment objects for interoperability with the Bioconductor ecosystem. License: GPL (>= 2) URL: https://bioconductor.org/packages/TiDEomics/, https://github.com/hte123/TiDEomics, https://hte123.github.io/TiDEomics BugReports: https://github.com/hte123/TiDEomics/issues biocViews: Software, GeneExpression, DifferentialExpression, Proteomics, Transcriptomics, TimeCourse, MultipleComparison, Pathways, Visualization, QualityControl Encoding: UTF-8 Roxygen: list(markdown = TRUE) Imports: circlize, clusterProfiler, ComplexHeatmap, dplyr, enrichplot, ggforce, ggh4x, ggplot2, ggplotify, ggpubr, ggrepel, ggridges, ggsci, limma, lme4, methods, patchwork, pbapply, PCAtools, randtests, scales, SummarizedExperiment, tibble, tidyr, Trendy, umap, WGCNA Depends: R (>= 4.5.0) LazyData: false Suggests: knitr, rmarkdown, BiocStyle, testthat (>= 3.1.0), plotly, enrichR, org.Hs.eg.db, org.Mm.eg.db, msigdbr, DeeDeeExperiment VignetteBuilder: knitr Config/testthat/edition: 3 Config/roxygen2/version: 8.1.1 Config/pak/sysreqs: libcairo2-dev cmake libfontconfig1-dev libfreetype6-dev libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev perl python3 zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-27 20:21:36 UTC RemoteUrl: https://github.com/bioc/TiDEomics RemoteRef: HEAD RemoteSha: 5a15b0c166428d09c651cb05ae26a90fa50bc66c NeedsCompilation: no Packaged: 2026-10-28 00:15:54 UTC; root Author: Tianen He [aut, cre] (ORCID: ) Maintainer: Tianen He