Package: TaxSEA Type: Package Title: Taxon Set Enrichment Analysis Version: 1.5.8 Authors@R: c(person("Feargal", "Ryan", email = "feargalr@gmail.com", role = c("aut", "cre","fnd"),comment = c(ORCID = "0000-0002-1565-4598", funding = "Supported by NHMRC Investigator Grant"))) Description: TaxSEA makes metagenomic data easier to interpret. Rather than reading species one at a time, it tests whether a-priori defined sets of taxa shift together, drawing on public databases (BugSigDB, MiMeDB, GutMGene, mBodyMap, BacDive and GMRepoV2) and on sets collated from the literature. Two approaches are provided. TaxSEA takes taxon names or NCBI IDs with a rank per taxon, such as a fold change or correlation coefficient, and tests each set with a Kolmogorov-Smirnov test. ssTaxSEA scores every set in a single sample as the mean centered log-ratio of its members, giving a per-sample value to use in any downstream model. Both work with any taxonomic profiling technology, including 16S rRNA gene sequencing, shotgun metagenomics and metatranscriptomics. License: GPL-3 Encoding: UTF-8 LazyData: false VignetteBuilder: knitr biocViews: Microbiome, Metagenomics, Sequencing, GeneSetEnrichment, RNASeq URL: https://github.com/feargalr/taxsea, https://feargalr.github.io/TaxSEA/ BugReports: https://github.com/feargalr/taxsea/issues Depends: R (>= 4.5.0) Suggests: BiocStyle, S4Vectors, bugsigdbr, fgsea, knitr, mia, rmarkdown, SummarizedExperiment, testthat Imports: methods, stats, utils Config/testthat/edition: 3 Config/roxygen2/version: 8.1.0 Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-26 06:37:55 UTC RemoteUrl: https://github.com/bioc/TaxSEA RemoteRef: HEAD RemoteSha: 9831356494cf3096773098dea7216393db07dffb NeedsCompilation: no Packaged: 2026-10-26 23:27:41 UTC; root Author: Feargal Ryan [aut, cre, fnd] (ORCID: , funding: Supported by NHMRC Investigator Grant) Maintainer: Feargal Ryan