Package: TVTB Type: Package Title: TVTB: The VCF Tool Box Version: 1.39.0 Date: 2025-08-05 Authors@R: person("Kevin", "Rue-Albrecht", role = c("aut", "cre"), email = "kevinrue67@gmail.com") Description: The package provides S4 classes and methods to filter, summarise and visualise genetic variation data stored in VCF files. In particular, the package extends the FilterRules class (S4Vectors package) to define news classes of filter rules applicable to the various slots of VCF objects. Functionalities are integrated and demonstrated in a Shiny web-application, the Shiny Variant Explorer (tSVE). License: Artistic-2.0 Depends: R (>= 3.4), methods, utils, stats Imports: AnnotationFilter, BiocGenerics (>= 0.25.1), BiocParallel, Biostrings, ensembldb, Seqinfo, GenomicRanges, GGally, ggplot2, Gviz, limma, IRanges (>= 2.21.6), reshape2, Rsamtools, S4Vectors (>= 0.25.14), SummarizedExperiment, VariantAnnotation (>= 1.19.9) Suggests: EnsDb.Hsapiens.v75 (>= 0.99.7), shiny (>= 0.13.2.9005), DT (>= 0.1.67), rtracklayer, BiocStyle (>= 2.5.19), knitr (>= 1.12), rmarkdown, testthat, covr, pander biocViews: Software, Genetics, GeneticVariability, GenomicVariation, DataRepresentation, GUI, Genetics, DNASeq, WholeGenome, Visualization, MultipleComparison, DataImport, VariantAnnotation, Sequencing, Coverage, Alignment, SequenceMatching Collate: utils.R tSVE.R AllClasses.R AllGenerics.R Genotypes-class.R TVTBparam-class.R VcfFilterRules-class.R parseCSQToGRanges.R countGenos-methods.R autodetectGenotypes.R addCountGenos-methods.R addFrequencies-methods.R addOverallFrequencies-methods.R addPhenoLevelFrequencies-methods.R dropInfo.R readVcf-methods.R variantsInSamples-methods.R vepInPhenoLevel-methods.R plotInfo.R pairsInfo.R show-methods.R VignetteBuilder: knitr URL: https://github.com/kevinrue/TVTB BugReports: https://github.com/kevinrue/TVTB/issues Config/Bioconductor/UnsupportedPlatforms: windows Config/pak/sysreqs: cmake make libbz2-dev libicu-dev libjpeg-dev liblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:44:36 UTC RemoteUrl: https://github.com/bioc/TVTB RemoteRef: HEAD RemoteSha: c77deb7c910e894acf8844311da6fcca42390faf NeedsCompilation: no Packaged: 2026-07-06 06:42:48 UTC; root Author: Kevin Rue-Albrecht [aut, cre] Maintainer: Kevin Rue-Albrecht