Package: TOAST Type: Package Title: Tools for the analysis of heterogeneous tissues Version: 1.27.0 Description: This package is devoted to analyzing high-throughput data (e.g. gene expression microarray, DNA methylation microarray, RNA-seq) from complex tissues. Current functionalities include 1. detect cell-type specific or cross-cell type differential signals 2. tree-based differential analysis 3. improve variable selection in reference-free deconvolution 4. partial reference-free deconvolution with prior knowledge. Author: Ziyi Li and Weiwei Zhang and Luxiao Chen and Hao Wu Maintainer: Ziyi Li License: GPL-2 Encoding: UTF-8 LazyData: false Depends: R (>= 3.6), EpiDISH, limma, nnls, quadprog biocViews: DNAMethylation, GeneExpression, DifferentialExpression, DifferentialMethylation, Microarray, GeneTarget, Epigenetics, MethylationArray BugReports: https://github.com/ziyili20/TOAST/issues Imports: stats, methods, SummarizedExperiment, corpcor, doParallel, parallel, ggplot2, tidyr, GGally Suggests: BiocStyle, knitr, rmarkdown, gplots, matrixStats, Matrix VignetteBuilder: knitr NeedsCompilation: no Packaged: 2026-07-04 04:32:19 UTC; root Config/pak/sysreqs: libicu-dev libpng-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:50:25 UTC RemoteUrl: https://github.com/bioc/TOAST RemoteRef: HEAD RemoteSha: a6f220997458acba9d0d89efc49a956263e5170e