Package: TMixClust Type: Package Title: Time Series Clustering of Gene Expression with Gaussian Mixed-Effects Models and Smoothing Splines Version: 1.35.0 Year: 2017 Date: 2017-06-04 Author: Monica Golumbeanu Maintainer: Monica Golumbeanu Description: Implementation of a clustering method for time series gene expression data based on mixed-effects models with Gaussian variables and non-parametric cubic splines estimation. The method can robustly account for the high levels of noise present in typical gene expression time series datasets. License: GPL (>=2) Depends: R (>= 3.4) biocViews: Software, StatisticalMethod, Clustering, TimeCourse, GeneExpression Imports: gss, mvtnorm, stats, zoo, cluster, utils, BiocParallel, flexclust, grDevices, graphics, Biobase, SPEM Suggests: rmarkdown, knitr, BiocStyle, testthat VignetteBuilder: knitr Encoding: UTF-8 LazyData: true RoxygenNote: 6.0.1 Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:46:14 UTC RemoteUrl: https://github.com/bioc/TMixClust RemoteRef: HEAD RemoteSha: 938d5d18b3347445bddc81a6a73bbebf9cfd2538 NeedsCompilation: no Packaged: 2026-05-30 09:42:02 UTC; root