Package: TMSig Type: Package Title: Tools for Molecular Signatures Version: 1.7.0 Date: 2024-10-17 Authors@R: c( person(given = "Tyler", family = "Sagendorf", email = "tyler.sagendorf@pnnl.gov", comment = c(ORCID = "0000-0003-1552-4870"), role = c("aut", "cre")), person(given = "Di", family = "Wu", role = "ctb"), person(given = "Gordon", family = "Smyth", role = "ctb") ) Description: The TMSig package contains tools to prepare, analyze, and visualize named lists of sets, with an emphasis on molecular signatures (such as gene or kinase sets). It includes fast, memory efficient functions to construct sparse incidence and similarity matrices and filter, cluster, invert, and decompose sets. Additionally, bubble heatmaps can be created to visualize the results of any differential or molecular signatures analysis. License: GPL (>= 3) URL: https://github.com/EMSL-Computing/TMSig BugReports: https://github.com/EMSL-Computing/TMSig/issues Encoding: UTF-8 RoxygenNote: 7.3.2 Roxygen: list(markdown = TRUE) VignetteBuilder: knitr biocViews: Clustering, GeneSetEnrichment, GraphAndNetwork, Pathways, Visualization Depends: R (>= 4.4.0), limma Imports: circlize, ComplexHeatmap, data.table, grDevices, grid, GSEABase, Matrix, methods, stats, utils Suggests: BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0) Config/testthat/edition: 3 Config/pak/sysreqs: libpng-dev libxml2-dev libssl-dev perl zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:04:00 UTC RemoteUrl: https://github.com/bioc/TMSig RemoteRef: HEAD RemoteSha: bb2a1ff6f28688dd43e4c1101ae4061e414a3d3b NeedsCompilation: no Packaged: 2026-07-04 07:53:14 UTC; root Author: Tyler Sagendorf [aut, cre] (ORCID: ), Di Wu [ctb], Gordon Smyth [ctb] Maintainer: Tyler Sagendorf