Package 'TBX20BamSubset'

Title: Subset of BAM files from the "TBX20" experiment
Description: Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function. A subset of the RNA-Seq data.
Authors: D. Bindreither
Maintainer: D. Bindreither <[email protected]>
License: LGPL
Version: 1.49.0
Built: 2026-10-10 10:31:02 UTC
Source: https://github.com/bioc/TBX20BamSubset

Help Index


Utilities returning the paths to BAM files of the data package

Description

The package contains 6 subset of BAM files from the TBX20 RNA-Seq experiment.

Details

The TBX20 data set basically provides ChIP-Seq and RNA-Seq data. In here only the RNA-Seq part of the data is utilized. TBX20 (T-box 20) is a transcriptional regulator essential for cardiac development and maintenance of mouse heart tissue. In this study TXB20 was knocked out by using a Tamoxifen mediated conditional knock-out system. Transcriptional changes caused by the ablation of the second exon of TBX20 result in rapid onset of heart failures and the subsequent death of the mice. TBX20 knock-out adult heart tissue was compared to wild type adult heart tissue. The associated RNA-Seq raw data can be retrieved by the following code chunk.

References

Noboru J. Sakabe, Ivy Aneas, Tao Shen, Leila Shokri, Soo-Young Park, Martha L. Bulyk, Sylvia M. Evans and Marcelo A. Nobrega Human Molecular Genetics Date: Feb 2012 Dual transcriptional activator and repressor roles of TBX20 regulateadult cardiac structure and function

Examples

bfs <- getBamFileList()

Retrieving file paths pointing to the BAM files.

Description

Retrieves the file paths for accessing the data of the TBX20BamSubset package.

Usage

getBamFileList(...)

Arguments

...

Arguments to be passed to or from methods.

Details

Accessory function to the BAM files of the TBX20BamSubset package.

Value

Returns a named character vector pointing to the BAM files included in TBX20BamSubset package.

Author(s)

D. Bindreither

See Also

TBX20BamSubset

Examples

bfl <- getBamFileList()
  bfl