Package: SpectralTAD Title: SpectralTAD: Hierarchical TAD detection using spectral clustering Version: 1.29.0 Authors@R: c( person(given = "Mikhail", family = "Dozmorov", role = c("aut", "cre"), email = "mikhail.dozmorov@gmail.com", comment = c(ORCID = "0000-0002-0086-8358")), person(given = "Kellen", family = "Cresswell", role = c("aut")), person(given = "John", family = "Stansfield", role = c("aut")) ) Description: SpectralTAD is an R package designed to identify Topologically Associated Domains (TADs) from Hi-C contact matrices. It uses a modified version of spectral clustering that uses a sliding window to quickly detect TADs. The function works on a range of different formats of contact matrices and returns a bed file of TAD coordinates. The method does not require users to adjust any parameters to work and gives them control over the number of hierarchical levels to be returned. License: MIT + file LICENSE Encoding: UTF-8 RoxygenNote: 7.2.3 Imports: dplyr, PRIMME, cluster, Matrix, parallel, BiocParallel, magrittr, HiCcompare, GenomicRanges, utils Suggests: BiocCheck, BiocManager, BiocStyle, knitr, rmarkdown, microbenchmark, testthat, covr Depends: R (>= 3.6) VignetteBuilder: knitr biocViews: Software, HiC, Sequencing, FeatureExtraction, Clustering BugReports: https://github.com/dozmorovlab/SpectralTAD/issues URL: https://github.com/dozmorovlab/SpectralTAD Config/pak/sysreqs: libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:49:37 UTC RemoteUrl: https://github.com/bioc/SpectralTAD RemoteRef: HEAD RemoteSha: a8c73aa854576d68d6b11bff3098a27c2fb59ad5 NeedsCompilation: no Packaged: 2026-07-04 05:38:45 UTC; root Author: Mikhail Dozmorov [aut, cre] (ORCID: ), Kellen Cresswell [aut], John Stansfield [aut] Maintainer: Mikhail Dozmorov