Package: SpNeigh Title: Spatial Neighborhood Modeling and Differential Expression Analysis for Transcriptomics Version: 1.1.0 Authors@R: person(given = "Jinming", family = "Cheng", email="jinming.cheng@outlook.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-3806-4694")) Description: SpNeigh provides methods for neighborhood-aware analysis of spatial transcriptomics data. It supports boundary detection, spatial weighting (centroid- and boundary-based), spatially informed differential expression using spline-based models, and spatial enrichment analysis via the Spatial Enrichment Index (SEI). Designed for compatibility with Seurat objects, SpatialExperiment objects and spatial data frames, SpNeigh enables interpretable, publication-ready analysis of spatial gene expression patterns. License: GPL (>= 3) Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Imports: concaveman, dbscan, dplyr, FNN, ggplot2, limma, magrittr, Matrix, methods, patchwork, purrr, rlang, scales, Seurat, sf, SingleCellExperiment, SpatialExperiment, splines, stringr, SummarizedExperiment, tibble, tidyr Suggests: BiocStyle, knitr, rmarkdown, SeuratObject, testthat (>= 3.0.0) biocViews: Spatial, SingleCell, GeneExpression, DifferentialExpression, Transcriptomics, Software URL: https://github.com/jinming-cheng/SpNeigh BugReports: https://github.com/jinming-cheng/SpNeigh/issues Depends: R (>= 4.4.0) VignetteBuilder: knitr Config/testthat/edition: 3 Config/pak/sysreqs: libabsl-dev cmake libgdal-dev gdal-bin libgeos-dev libglpk-dev make libmagick++-dev gsfonts libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev libproj-dev python3 libsqlite3-dev libudunits2-dev libnode-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:06:43 UTC RemoteUrl: https://github.com/bioc/SpNeigh RemoteRef: HEAD RemoteSha: bfc471bc69896c75d10c3f21f38fd6cf4c049066 NeedsCompilation: no Packaged: 2026-05-30 09:47:36 UTC; root Author: Jinming Cheng [aut, cre] (ORCID: ) Maintainer: Jinming Cheng