Package: SingleCellAlleleExperiment Title: S4 Class for Single Cell Data with Allele and Functional Levels for Immune Genes Version: 1.9.0 Authors@R: c( person("Jonas", "Schuck", email="jschuckdev@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0009-0003-5705-4579")), person("Ahmad", "Al Ajami", role = c("aut"), comment = c(ORCID = "0009-0006-5615-7447")), person("Federico", "Marini", role = c("aut"), comment = c(ORCID = "0000-0003-3252-7758")), person("Katharina", "Imkeller", role = c("aut"), comment = c(ORCID = "0000-0002-5177-0852"))) Description: Defines a S4 class that is based on SingleCellExperiment. In addition to the usual gene layer the object can also store data for immune genes such as HLAs, Igs and KIRs at allele and functional level. The package is part of a workflow named single-cell ImmunoGenomic Diversity (scIGD), that firstly incorporates allele-aware quantification data for immune genes. This new data can then be used with the here implemented data structure and functionalities for further data handling and data analysis. License: MIT + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Depends: R (>= 4.4.0), SingleCellExperiment Imports: SummarizedExperiment, BiocParallel, DelayedArray, methods, utils, Matrix, S4Vectors, stats Suggests: scaeData, knitr, rmarkdown, BiocStyle, scran, scater, scuttle, ggplot2, patchwork, org.Hs.eg.db, AnnotationDbi, DropletUtils, testthat (>= 3.0.0) biocViews: DataRepresentation, Infrastructure, SingleCell, Transcriptomics, GeneExpression, Genetics, ImmunoOncology, DataImport URL: https://github.com/AGImkeller/SingleCellAlleleExperiment BugReports: https://github.com/AGImkeller/SingleCellAlleleExperiment/issues VignetteBuilder: knitr Config/testthat/edition: 3 Config/pak/sysreqs: zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:03:05 UTC RemoteUrl: https://github.com/bioc/SingleCellAlleleExperiment RemoteRef: HEAD RemoteSha: 9fb15ed615ba18146b177d0275e670a2892e49a9 NeedsCompilation: no Packaged: 2026-05-30 09:49:14 UTC; root Author: Jonas Schuck [aut, cre] (ORCID: ), Ahmad Al Ajami [aut] (ORCID: ), Federico Marini [aut] (ORCID: ), Katharina Imkeller [aut] (ORCID: ) Maintainer: Jonas Schuck