Package: SimBu
Title: Simulate Bulk RNA-seq Datasets from Single-Cell Datasets
Version: 1.15.0
Authors@R: 
    person(given = "Alexander",
           family = "Dietrich",
           role = c("aut", "cre"),
           email = "alex.dietrich@tum.de")
Description: SimBu can be used to simulate bulk RNA-seq datasets with
        known cell type fractions. You can either use your own
        single-cell study for the simulation or the sfaira database.
        Different pre-defined simulation scenarios exist, as are
        options to run custom simulations. Additionally, expression
        values can be adapted by adding an mRNA bias, which produces
        more biologically relevant simulations.
License: GPL-3 + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.3
Imports: basilisk, BiocParallel, data.table, dplyr, ggplot2, tools,
        Matrix (>= 1.3.3), methods, phyloseq, proxyC, RColorBrewer,
        RCurl, reticulate, sparseMatrixStats, SummarizedExperiment,
        tidyr
Suggests: curl, knitr, matrixStats, rmarkdown, Seurat (>= 5.0.0),
        SeuratObject (>= 5.0.0), testthat (>= 3.0.0)
URL: https://github.com/omnideconv/SimBu
BugReports: https://github.com/omnideconv/SimBu/issues
VignetteBuilder: knitr
Config/testthat/edition: 3
StagedInstall: no
biocViews: Software, RNASeq, SingleCell
Config/pak/sysreqs: libglpk-dev make libicu-dev libpng-dev libxml2-dev
        python3 zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:58:50 UTC
RemoteUrl: https://github.com/bioc/SimBu
RemoteRef: HEAD
RemoteSha: e4a5ee259a3bee5cc6b4fa3e2ed77e85a751c516
NeedsCompilation: no
Packaged: 2026-07-04 03:38:44 UTC; root
Author: Alexander Dietrich [aut, cre]
Maintainer: Alexander Dietrich <alex.dietrich@tum.de>