# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "SigCheck" in publications use:' type: software license: Artistic-2.0 title: 'SigCheck: Check a gene signature''s prognostic performance against random signatures, known signatures, and permuted data/metadata' version: 2.37.0 abstract: While gene signatures are frequently used to predict phenotypes (e.g. predict prognosis of cancer patients), it it not always clear how optimal or meaningful they are (cf David Venet, Jacques E. Dumont, and Vincent Detours' paper "Most Random Gene Expression Signatures Are Significantly Associated with Breast Cancer Outcome"). Based on suggestions in that paper, SigCheck accepts a data set (as an ExpressionSet) and a gene signature, and compares its performance on survival and/or classification tasks against a) random gene signatures of the same length; b) known, related and unrelated gene signatures; and c) permuted data and/or metadata. authors: - family-names: Stark given-names: Rory email: rory.stark@cruk.cam.ac.uk - family-names: Norden given-names: Justin repository: https://bioc.r-universe.dev contact: - family-names: Stark given-names: Rory email: rory.stark@cruk.cam.ac.uk