Package: SPIAT Type: Package Title: Spatial Image Analysis of Tissues Version: 1.15.0 Authors@R: c( person(given = "Anna", family="Trigos", role=c("aut"), comment = c(ORCID = "0000-0002-5915-2952"), email="anna.trigos@petermac.org"), person(given = "Yuzhou", family = " Feng", role=c("aut", "cre"), comment = c(ORCID = "0000-0002-2955-4053"), email="yuzhou0610@gmail.com"), person(given = "Tianpei", family = " Yang", role="aut", email="yangtp3344@gmail.com"), person(given = "Mabel", family = " Li", role="aut"), person(given = "John", family = " Zhu", role="aut"), person(given = "Volkan", family=" Ozcoban", role="aut", email = "volkanozcoban1@gmail.com"), person(given = "Maria", family= "Doyle", role="aut", email = "maria.doyle@petermac.org")) Description: SPIAT (**Sp**atial **I**mage **A**nalysis of **T**issues) is an R package with a suite of data processing, quality control, visualization and data analysis tools. SPIAT is compatible with data generated from single-cell spatial proteomics platforms (e.g. OPAL, CODEX, MIBI, cellprofiler). SPIAT reads spatial data in the form of X and Y coordinates of cells, marker intensities and cell phenotypes. SPIAT includes six analysis modules that allow visualization, calculation of cell colocalization, categorization of the immune microenvironment relative to tumor areas, analysis of cellular neighborhoods, and the quantification of spatial heterogeneity, providing a comprehensive toolkit for spatial data analysis. License: Artistic-2.0 + file LICENSE Encoding: UTF-8 Depends: R (>= 4.2.0), SpatialExperiment (>= 1.8.0) Imports: apcluster (>= 1.4.7), ggplot2 (>= 3.2.1), gridExtra (>= 2.3), gtools (>= 3.8.1), reshape2 (>= 1.4.3), dplyr (>= 0.8.3), RANN (>= 2.6.1), pracma (>= 2.2.5), dbscan (>= 1.1-5), mmand (>= 1.5.4), tibble (>= 2.1.3), grDevices, stats, utils, vroom, dittoSeq, spatstat.geom, methods, spatstat.explore, raster, sp, SummarizedExperiment, rlang Suggests: BiocStyle, plotly (>= 4.9.0), knitr, rmarkdown, pkgdown, testthat, graphics, alphahull, Rtsne, umap, ComplexHeatmap, elsa biocViews: BiomedicalInformatics, CellBiology, Spatial, Clustering, DataImport, ImmunoOncology, QualityControl, SingleCell, Software, Visualization BugReports: https://github.com/trigosteam/SPIAT/issues RoxygenNote: 7.3.1 LazyData: true VignetteBuilder: knitr URL: https://trigosteam.github.io/SPIAT/ Config/pak/sysreqs: libgdal-dev gdal-bin libgeos-dev libmagick++-dev gsfonts libicu-dev libssl-dev libproj-dev libsqlite3-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:59:05 UTC RemoteUrl: https://github.com/bioc/SPIAT RemoteRef: HEAD RemoteSha: 7e6bef6188fc1be6db97d842a591c2bff5623a54 NeedsCompilation: no Packaged: 2026-06-19 07:36:14 UTC; root Author: Anna Trigos [aut] (ORCID: ), Yuzhou Feng [aut, cre] (ORCID: ), Tianpei Yang [aut], Mabel Li [aut], John Zhu [aut], Volkan Ozcoban [aut], Maria Doyle [aut] Maintainer: Yuzhou Feng