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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "SNPRelate" in publications use:'
type: software
license: GPL-3.0-only
title: 'SNPRelate: Parallel Computing Toolset for Relatedness and Principal Component
  Analysis of SNP Data'
version: 1.39.1
doi: 10.1093/bioinformatics/bts606
identifiers:
- type: doi
  value: 10.32614/CRAN.package.SNPRelate
abstract: 'Genome-wide association studies (GWAS) are widely used to investigate the
  genetic basis of diseases and traits, but they pose many computational challenges.
  We developed an R package SNPRelate to provide a binary format for single-nucleotide
  polymorphism (SNP) data in GWAS utilizing CoreArray Genomic Data Structure (GDS)
  data files. The GDS format offers the efficient operations specifically designed
  for integers with two bits, since a SNP could occupy only two bits. SNPRelate is
  also designed to accelerate two key computations on SNP data using parallel computing
  for multi-core symmetric multiprocessing computer architectures: Principal Component
  Analysis (PCA) and relatedness analysis using Identity-By-Descent measures. The
  SNP GDS format is also used by the GWASTools package with the support of S4 classes
  and generic functions. The extended GDS format is implemented in the SeqArray package
  to support the storage of single nucleotide variations (SNVs), insertion/deletion
  polymorphism (indel) and structural variation calls in whole-genome and whole-exome
  variant data.'
authors:
- family-names: Zheng
  given-names: Xiuwen
  email: zhengx@u.washington.edu
  orcid: https://orcid.org/0000-0002-1390-0708
preferred-citation:
  type: article
  title: A High-performance Computing Toolset for Relatedness and Principal Component
    Analysis of SNP Data
  authors:
  - family-names: Zheng
    given-names: Xiuwen
    email: zhengx@u.washington.edu
    orcid: https://orcid.org/0000-0002-1390-0708
  - family-names: Levine
    given-names: David
  - family-names: Shen
    given-names: Jess
  - family-names: Gogarten
    given-names: Stephanie
  - family-names: Laurie
    given-names: Cathy
  - family-names: Weir
    given-names: Bruce
  journal: Bioinformatics
  year: '2012'
  doi: 10.1093/bioinformatics/bts606
  volume: '28'
  issue: '24'
  start: 3326-3328
repository: https://bioc.r-universe.dev
repository-code: https://github.com/zhengxwen/SNPRelate
commit: d1a43a2bac1e7e22e0dd22364f06ba8f2cb5dbe4
url: https://github.com/zhengxwen/SNPRelate
date-released: '2024-09-26'
contact:
- family-names: Zheng
  given-names: Xiuwen
  email: zhengx@u.washington.edu
  orcid: https://orcid.org/0000-0002-1390-0708