Changes in version 0.99.5 o Fixed bugs according to defining the ROTS runs. o Fixed some bugs related to plotting the findings with plotFindings. o Generalized some code better. o Removed unused code. o Complemented input validation. Changes in version 0.99.4 o Updated version dependency to R to 4.2.0. Changes in version 0.99.3 o Added Bioconductor installation instructions in the Vignette. o Fixed some bugs related to changing coding practices in v. 0.99.2 Changes in version 0.99.2 o Added a NEWS file. o Added Bioconductor installation instructions in README. o Removed separate licence file. Using GPL-3 licence. o Added information for the included datasets. o Added table of contents for the vignette. o Updated the RolDE main functions documentation. o Improved coding practices to match more Bioconductor style. Changes in version 0.99.1 o Submitted to Bioconductor.