Changes in version 1.25.1 (2026-01-28)                 

    o   Adapted code due to changes in Seurat V5

                 Changes in version 1.21.1 (2024-11-07)                 

    o   Added new functions to perform quantitative comparative pathway analyses for scRNA-seq data.

                 Changes in version 1.17.3 (2024-02-01)                 

    o   Fixed a bug in vignette showcasing the reanalysis of public data.

                 Changes in version 1.17.2 (2023-11-28)                 

    o   Added a set of new functions to support ReactomeGSA's features to load public datasets.

    o   Added a new vignette to showcase how public datasets can easily be loaded using the ReactomeGSA package.

                       Changes in version 1.17.1                        

    o   Fixed vignettes

                 Changes in version 1.13.1 (2023-04-13)                 

    o   Fixed documentation mismatch in "plot_heatmap"

                 Changes in version 1.9.1 (2021-11-05)                  

    o   Adapted default FDR threshold in "plot_heatmap" to match other functions.

                 Changes in version 1.7.5 (2021-09-28)                  

    o   Fixed documentation of "plot_heatmap"

                 Changes in version 1.7.4 (2021-09-24)                  

    o   Added new plotting function "plot_heatmap"

                 Changes in version 1.7.3 (2021-09-14)                  

    o   Updated vignette to introduce the "open_reactome" command

                 Changes in version 1.7.2 (2021-09-09)                  

    o   Fixed timeout issue during large requests in perform_reactome_analysis 

                 Changes in version 1.7.1 (2021-06-09)                  

    o   Fixed bug in scRNA-seq vignette.

                 Changes in version 1.5.2 (2021-04-16)                  

    o   Added check to ensure that clustering was performed in Seurat objects prior to the pathway analysis.

                 Changes in version 1.5.1 (2021-04-01)                  

    o   Fixed bug in perform_reactome_analysis: Error messages were not displayed correctly.

                 Changes in version 1.3.7 (2020-09-29)                  

    o   Fixed bug in plot_gsva_pathway

                 Changes in version 1.3.6 (2020-09-01)                  

    o   Improved analyse_sc_clusters for SingleCellExperiment objects to define cell grouping using factors and a single character string specifying the metada field.

                 Changes in version 1.3.4 (2020-09-01)                  

    o   Fixed bug in analyse_sc_clusters when processing SingleCellExperiment objects.

                 Changes in version 1.3.3 (2020-05-26)                  

    o   Updated documentation

                 Changes in version 1.3.2 (2020-05-26)                  

    o   Added workaround for SEC_E_ILLEGAL_MESSAGE error on older Windows systems.

                 Changes in version 1.3.1 (2020-04-29)                  

    o   Added option to hide non-significant pathway in plot_correlations

                 Changes in version 1.1.4 (2020-04-20)                  

    o   bioRxiv paper is out!

                 Changes in version 1.1.3 (2020-04-11)                  

    o   Added custom function to calculate average cluster expression for Seurat objects

                 Changes in version 1.1.2 (2020-03-13)                  

    o   Add support manually track the status of submitted analyses

    o   Added additional signature to add_dataset to support expression values as matrix

                 Changes in version 1.1.1 (2020-02-19)                  

    o   Compress JSON requests using gzip to improve performance for large datasets

                 Changes in version 0.99.8 (2019-08-13)                 

    o   Removed package startup message

    o   Changed spelling of name to ReactomeGSA

    o   Removed all default values from the method signatures

    o   Added constructor function for the ReactomeAnalysisRequest class.

                 Changes in version 0.99.7 (2019-07-22)                 

    o   Adapted the get_reactome_methods function to provide a more readable overview

    o   Changed to reactome analysis service API URL to the new domain name.

                 Changes in version 0.99.6 (2019-07-09)                 

    o   Minor bugfixes in examples

                 Changes in version 0.99.5 (2019-07-09)                 

    o   Updated vignette to new API data types

    o   Added new function remove_dataset

    o   Fixed bugs when overwriting existing datasets in AnalysisRequests

    o   Fixed bug that pathways function did not sort the pathway table

                 Changes in version 0.99.0 (2019-07-01)                 

    o   Submitted to Bioconductor